Aha ngwaahịa:Lemairamin (WGX-50)

Aha ọzọ:2-Propenamide, N-[2- (3,4-dimethoxyphenyl) ethyl] -3-phenyl-, (2E) -; Lemairamin (WGX-50)

CAS Mba:29946-61-0

Nyocha: 98.0%Min

Agba: White ruo na-acha ọcha ntụ ntụ

Nkwakọ ngwaahịa:25kg/DRUM

Lemairamin ma ọ bụ Wgx50 bụ ngwakọta okike ewepụtara na ose chili nke gosipụtara nsonaazụ na-ekwe nkwa igbochi ọrịa Alzheimer. Nnyocha achọpụtala na ọ nwere ike igbochi Aβ- akpalite neuronal apoptosis, belata neuronal calcium toxicity, ma belata mkpokọta nke Aβ oligomers na cerebral cortex. Na mgbakwunye, egosiri wgx50 ka ọ kwalite arụmọrụ ọgụgụ isi na ụmụ oke. Nnyocha na-egosi na wgx50 nwere ikike igbochi mgbakọ protein-protein n'etiti ụmụ irighiri ihe amyloid. N'ozuzu, wgx50 nwere ikike igbochi ọrịa Alzheimer ma nwee ike ịnye ụzọ ọhụrụ maka ịmepụta ọgwụ na-elekwasị anya A.β ndị oligomer. Tụkwasị na nke ahụ, WGX-50 na-egosipụta ọrụ mgbochi mkpali dị ịrịba ama, nke na-eme ka ọ bụrụ onye na-ekwe nkwa maka ọgwụgwọ ọrịa ndị na-egbuke egbuke. A chọpụtala na WGX-50 nwere mmetụta dị ukwuu na akpụkpọ ahụ, dị ka ibelata wrinkles na ime ka akpụkpọ ahụ dịkwuo mma. Na mgbakwunye na ogige ndị sitere n'okike ewepụtara na osisi Zanthoxylum bungeanum, enwere ugbu a ọtụtụ ogige synthetic nke a na-eji na ngwa dị iche iche ma dabara adaba maka ahịa.

Ọrụ:

1. Mmetụta analgesic: Xanthoxylin nwere mmetụta analgesic ma nwee ike belata mgbaàmà mgbu. Ọ pụrụ ịkpali ndị na-anabata okpomọkụ nke ahụ, gbanwee ụzọ a na-esi ebute mgbu, ma hapụ ihe ndị na-eme ka ahụ́ mgbu kwụsịlata, si otú ahụ na-ebelata ahụ erughị ala dị ka isi ọwụwa na ọrịa ogbu na nkwonkwo.
2. Mmetụta nje bacteria: Xanthophyllin nwere mmetụta antibacterial ụfọdụ, nke nwere ike igbochi uto nke nje bacteria na fungi. A na-eji ya n'ọtụtụ ebe na ụlọ ọrụ nri na ngwaahịa nlekọta ahụike iji mee ka nri dị ọhụrụ ma gbasaa ndụ ya.
3. Na-akwalite mgbaze: Xanthoxylum nwere ike kpalie nzuzo nke glands digestive, na-amụba ihe nzuzo nke ihe ọṅụṅụ gastric na saliva, si otú ahụ na-akwalite usoro mgbaze nri. Ọ nwekwara ike belata nsogbu GI dị ka cramps GI na reflux acid.
4. Mmetụta Antioxidant: Xanthophyllin bụ antioxidant siri ike nke nwere ike wepụ ihe ndị na-akpata free radicals ma belata mmebi nke mkpụrụ ndụ nke nrụgide oxidative kpatara. Nke a na-enyere aka ịka nká cellular, na-echebe ahụike obi na akwara ozi, ma gbochie mmepe nke ọrịa na-adịghị ala ala.

Ngwa:

Lemairamin bụ ngwakọta amide ewepụtara na ogbugbo nke osisi Zanthoxylum bungeanum. A na-eji ya eme ihe ugbu a dị ka ihe mgbakwunye nri, ọ na-arụkwa ọrụ dị ka agonist nke alpha7 nicotinic acetylcholine receptor (α7nAChR), nke na-ebelata neuroinflammation na ọrịa Alzheimer. α7nAChR), nke na-ebelata neuroinflammation na ọrịa Alzheimer, yana kpamkpam synthetic.Wgx50 egosila ihe na-agba ume na ọmụmụ ihe ọmụmụ, gụnyere igbochi Aβ-induced neuronal apoptosis, ibelata neuronal calcium toxicity, na-ebelata mkpokọta Aβ oligomer na ụbụrụ ụbụrụ, na imeziwanye arụmọrụ ọgụgụ isi na ụmụ oke.