J-147 ntụ ntụ

Oyiyi egosipụtara ntụ ntụ J-147
  • J-147 ntụ ntụ

Nkọwa dị mkpirikpi:

J147 bụ J-147 bụ ihe pụrụ iche nwere ike, ọnụ na-arụsi ọrụ ike na nke ukwuu neuroprotective compound nwere ike welie ebe nchekwa na nkịtị anụmanụ yana igbochi ebe nchekwa deficits na ọrịa Alzheimer (AD) transgenic ụmụ oke. A na-ejikọta ọrụ neurotrophic na ebe nchekwa nchekwa nke J-147 na mmụba nke ụbụrụ na-enweta ụbụrụ neurotrophic (BDNF) na nkwupụta nke protein na-anabata BDNF, nkwalite nke LTP, nchekwa nke protein synaptic, mbelata amyloid plaques.


  • Ọnụ ego FOB:US $0.5-2000/KG
  • Ọnụ ọgụgụ nke Min.1KG
  • Ikike inye:10000 KG / kwa ọnwa
  • Port:SHANGHAI/BEIJING
  • Usoro ịkwụ ụgwọ:L/C,D/A,D/P,T/T
  • :
    • Budata dị ka PDF

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Aha ngwaahịa:J-147 ntụ ntụ

    Aha ọzọ:2,2,2-Trifluoroacetic acid 1- (2,4-DiMethylphenyl) -2-[(3-Methoxyphenyl) Methylene] hydrazide],J-147, J147

    CAS Mba:1146963-51-0

    Nyocha: 99.0% nkeji

    Agba: White ntụ ntụ

    Nkwakọ ngwaahịa: 25kgs Drum

     

    J-147bụ neuroprotectant na-arụsi ọrụ ike nke ukwuu nke sitere na curcumin, ihe na-arụ ọrụ na turmeric. N'adịghị ka curcumin, ọ na-agafe ihe mgbochi ụbụrụ ọbara nke ọma.

    J-147 bụ ihe pụrụ iche nwere ike, na-arụ ọrụ ọnụ, onye na-ahụ maka neuroprotective maka nkwalite ọgụgụ isi.
    J-147 nwere ike ịfefe ihe mgbochi ụbụrụ ọbara (BBB) ​​ngwa ngwa. J-147 nwere ike igbochi monoamine oxidase B (MAO B) na onye na-ebugharị dopamine nwere ụkpụrụ EC50 nke 1.88 μM na 0.649 μM, n'otu n'otu. J-147 nwere ikike maka ọgwụgwọ ọrịa Alzheimer

    J-147 bụ neuroprotectant na-arụ ọrụ nke ọma nke sitere na curcumin, ihe na-arụ ọrụ na turmeric. N'adịghị ka curcumin, ọ na-agafe ihe mgbochi ụbụrụ ọbara nke ọma. N'ime ha, J-147 na-arụ ọrụ site na ijikọ ATP synthase. Mmepụta nke ATP na-ejikọta ya na usoro ịka nká. Na mgbakwunye na ịbawanye ọkwa nke neurotransmitters NGF na BDNF, J-147 nwere ike ịchịkwa nke a. Na mgbakwunye, J-147 na-egbochi monoamine oxidase B na dopamine transporter. Na-akwalite uto ụbụrụ site n'ịbawanye ọkwa nke ihe na-eto eto (NGF) na ụbụrụ neurotrophic factor (BDNF). Nke kachasị mkpa, J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, kwalite ikike mmụta na ebe nchekwa ụbụrụ, ma melite ọrụ ọgụgụ isi.

    Ọrụ:

    J-147 nwere ike ịfefe ihe mgbochi ụbụrụ ọbara (BBB) ​​ngwa ngwa.
    J-147 nwere ike igbochi monoamine oxidase B (MAO B) na onye na-ebugharị dopamine nwere ụkpụrụ EC50 nke 1.88 μM na 0.649 μM, n'otu n'otu.
    J-147 nwere ikike maka ọgwụgwọ ọrịa Alzheimer (AD).
    J-147 nwere ikike maka ọgwụgwọ ọrịa Alzheimer (AD).

    Ngwa:

    J-147 bụ ihe sịntetik nke usoro ọrụ ya bụ isi na-agụnye nkwalite mitochondrial, si otú ahụ na-ebuli mmepụta ike na ọkwa cellular. Emebere J-147 iji kwalite ikike ụbụrụ imezi yana chebe onwe ya pụọ ​​​​na mmebi metụtara afọ site na imeziwanye ọrụ mitochondrial. Na mgbakwunye, J-147 na-egosipụta ihe mgbochi mkpali na ihe antioxidant, na-eme ka mmetụta neuroprotective ya dịkwuo elu. J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, kwalite ikike mmụta na ebe nchekwa ụbụrụ, ma melite ọrụ ọgụgụ isi.

  • Nke gara aga:
  • Osote:

    • Ngwaahịa ndị metụtara