Beta-nicotinamide Mononucleotide (NMN), ngwaahịa sitere na mmeghachi omume NAMPT yana isi NAD + etiti, na-eme ka nnabata glucose dịkwuo mma site na iweghachi ọkwa NAD + na ụmụ oke T2D kpatara HFD.NMN na-akwalitekwa mmetụta insulin imeju ma weghachi okwu mkpụrụ ndụ ihe nketa metụtara nrụgide oxidative, nzaghachi mkpali, na rhythm circadian, akụkụ site na ịgbalite SIRT1.A na-eji NMN maka ọmụmụ ihe ejikọtara n'ime RNA aptamers na usoro ịgbalite ribozyme gụnyere β-nicotinamide mononucleotide (Beta-NMN) -arụ ọrụ RNA iberibe.
Nicotinamide mononucleotide ("NMN" na "β-NMN") bụ nucleotide sitere na ribose na nicotinamide.Niacinamide (nicotinamide,) bụ ụdị vitamin B3 (niacin.) Dị ka biochemical precursor nke NAD +, ọ nwere ike bara uru na mgbochi nke pellagra.
Ụdị ya na-enweghị uche, niacin, dị n'ụdị nri dị iche iche: ahụekere, ero (portobello, grilled), Avocados, Green Peas (ọhụrụ), na ụfọdụ azụ na anụ anụmanụ.
N'ime ọmụmụ [na ụmụ oke], NMN egosila na ọ ga-agbanwe ọrụ akwara afọ metụtara afọ site na ibelata nrụgide oxidative.
Aha: Beta-Nicotinamide Mononucleotide
CAS : 1094-61-7
Aha ngwaahịa: Beta-Nicotinamide Mononucleotide;NMN
Aha ndị ọzọ: β-D-NMN; BETA-NMN; beta-D-NMN; NMN zwitterion; Nicotinamide Ribotide; Nicotinamide nucleotide; Nicotimide mononucleotide; Nicotinamide mononuclotide
CAS: 1094-61-7
Usoro ihe omimi: C11H15N2O8P
Arọ Molecular: 334.22
Ịdị ọcha: 98%
Nchekwa okpomọkụ: 2-8°C
Ọdịdị: White ntụ ntụ
Jiri: mgbochi ịka nká
Ọrụ:
1.Nicotinamide mononucleotide na mkpụrụ ndụ mmadụ na-arụ ọrụ dị mkpa na ike ike ike, ọ na-etinye aka na intracellular NAD (nicotinamide adenine dinucleotide, cell energy convert important coenzyme) njikọ, nke a na-eji na-egbochi ịka nká, ịdaba shuga ọbara na ngwaahịa nlekọta ahụike ndị ọzọ.
2. Nicotinamide Mononucleotide bụ vitamin soluble mmiri, ngwaahịa a na-acha ọcha crystalline ntụ ntụ, odorless ma ọ bụ fọrọ nke nta ka odorless, ilu na uto, kpamkpam soluble na mmiri ma ọ bụ ethanol, dissolvable na glycerin.
3.Nicotinamide Mononucleotide dị mfe itinye ọnụ, enwere ike kesaa ya n'ime ahụ, ngafe metabolites ma ọ bụ prototype na-ewepụ ngwa ngwa site na mmamịrị.Nicotinamide bụ akụkụ nke coenzyme I na coenzyme II, na-arụ ọrụ nke nnyefe hydrogen na biological oxidation respiratory chain, nwere ike ịkwalite usoro oxidation nke ndụ na metabolism anụ ahụ, na-echekwa anụ ahụ nkịtị (karịsịa akpụkpọ ahụ, tract digestive na sistem ụjọ) iguzosi ike n'ezi ihe nwere ọrụ dị mkpa. .
Na mgbakwunye, nicotinamide nwere mgbochi na ọgwụgwọ nke nkụchi obi, sinus node function and anti-fast experimental arrhythmias, nicotinamide nwere ike ime ka obi obi dịkwuo elu na ngọngọ atrioventricular nke verapamil kpatara.
