Dzina lazogulitsa:Mtengo wa 7P

Dzina Lina:Compound7P;2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide ;2-(N-(2-methoxyphenyl)-4- methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide

Nambala ya CAS:1890208-58-8

Zofunika: 99.0%

Mtundu: ufa woyera wokhala ndi fungo labwino komanso kukoma kwake

Mkhalidwe wa GMO: GMO Yaulere

Kulongedza: mu 25kgs fiber ng'oma

Kusungirako: Sungani chidebe chosatsegulidwa pamalo ozizira, owuma, Khalani kutali ndi kuwala kwamphamvu

Shelf Life: Miyezi 24 kuyambira tsiku lopangidwa

Compound 7p inasonyezedwa kuti ipangitse kukula kwa ma axon a GAP-43-positive mu chitsanzo cha nyama cha kuvulala kwa mitsempha ya optic, kutanthauza kuti ntchito ya neurite outgrowth ya 7p mu vitro imatanthawuza kulimbikitsanso kusinthika kwa axon mu Vivo.

Mu chitsanzo cha nyama cha optic nerve kuvulala, 7p inasonyezedwa kuti ipangitse kukula kwa gap-43 ma axon abwino, kusonyeza kuti in vitro neurite outgrowth activity of compound 7p imatanthawuza kukondoweza kwa axon regeneration mu vivo. za njira zomwe zimathandizira kusinthika kwa axon mu vivo zidzapereka maziko omveka kuti ayesetse mtsogolo kuti apititse patsogolo njira zothandizira.

Compound 7P imatanthawuza chinthu china chamoyo chomwe chili ndi maatomu asanu ndi awiri a carbon. Mu organic chemistry, mpweya ndi chinthu chofunikira kwambiri chifukwa ukhoza kupanga mgwirizano wolimba ndi maatomu ena, kuphatikizapo maatomu a carbon, kupanga mamolekyu ovuta. Mamolekyuwa amatha kukhala ndi zinthu zosiyanasiyana komanso ntchito zosiyanasiyana, zomwe zimapangitsa kuti zinthu za carbon zikhale zomangira moyo. Mu zitsanzo za zinyama za kuvulala kwa mitsempha ya optic, 7p inasonyezedwa kuti ipangitse kukula kwa ma axon a GAP-43-positive, kutanthauza kuti ntchito ya kukula kwa neurite ya 7p mu vitro imatanthawuza kulimbikitsa kusinthika kwa axonal mu vivo. Compound 7P ufa ndi ufa woyera mpaka woyera wopangidwa ngati tandem pawiri kuti azindikire awiri-acting thromboxane receptor antagonist inhibitors. M'malo mwake, pawiri 7p idawonetsa kusankha kwa prostaglandin I2 synthase (PTGIS, CYP8A1) yokhudzana ndi thromboxane synthase (CYP5A1). Mankhwala a nootropic 7P ufa amalimbikitsa kukula kwa axon a Gap-43-positive, motero amalimbikitsa kusinthika kwa axonal m'thupi. Complex 7p yapamwamba kwambiri idapangidwa kuti izithandizira kulumikizana, kusintha malingaliro ndikuthandizira kuthana ndi kutopa. Imalepheretsanso kutulutsa okosijeni muubongo ndipo imathandizira kuthana ndi kuwonongeka kwa ubongo chifukwa chakumwa mowa.

Ntchito:

Kubadwanso kwa axon pambuyo povulazidwa m'kati mwa mitsempha yapakati kumalephereka pang'onopang'ono chifukwa ngati kuchepa kwa zaka kumadalira mphamvu ya kukula kwa axon, ndipo imodzi mwa njira zothandizira kukula kwa axon mu neurons yovulala imaphatikizapo kugwiritsira ntchito mankhwala osokoneza bongo. phenotypic cell-based screen ya library library ndi kukhathamiritsa kotsogozedwa ndi zochitika zomwe zidapangitsa kuti pakhale kuzindikirika kwa 7p komwe amalimbikitsa kukula kwa neurite kwa ma neuron otukuka omwe amachokera ku hippocampus, cerebral cortex, ndi retina. mu chinyama cha optic nerve kuvulala, pawiri 7p inasonyezedwa kuti ipangitse kukula kwa gap-43 ma axon abwino, kusonyeza kuti mu vitro neurite outgrowth ntchito ya compound 7p imatanthawuza kukondoweza kwa axon regeneration mu vivo. za njira zomwe zimathandizira kusinthika kwa axon mu vivo zidzapereka maziko omveka kuti ayesetse mtsogolo kuti apititse patsogolo njira zothandizira.
Ntchito:

Tsopano ndi mankhwala anzeru a nootropic omwe amadziwonetsera okha mu imodzi mwama racetams amphamvu kwambiri m'chilengedwe cha nootropic. Amapangidwa kuchokera kumagulu amagulu otchedwa racetams, komanso osagwiritsa ntchito acetylcholine okha komanso GABA receptors mu ubongo, izi zimatha kuyambitsa cholinergic ndi glutamate receptors za cerebral cortex, ndipo ndi mankhwala osinthika a racetam chifukwa cha mphamvu zake zazikulu. njira yapadera yochitira zinthu. Fasoracetam pakali pano ikuwonetsanso zopindulitsa monga anti-depressant, ADHD stimulant, ndi anxiolytic, komanso, monga zatsimikiziridwa m'ma laboratories m'dziko lonselo, zimathandiza kupanga ndi kusunga kukumbukira kwatsopano.