Dzina la malonda:Gamma-glutamylcysteine ufa
Mawu ofanana: gamma-L-Glutamyl-L-cysteine, γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, GGC, (2S) -2-Amino-5-{[(1R) -1-carboxy-2- sulfanylethyl]amino}-5-oxopentanoic acid, cysteine, Continual-G
Molecular formula: C8H14N2O5S
Molecular Kulemera kwake: 250.27
Nambala ya CAS: 686-58-8
Maonekedwe / mtundu: White crystalline ufa
Kusungunuka: Kusungunuka m'madzi
Ubwino: kalambulabwalo wa glutathione
Gamma-glutamylcysteinendi dipeptide ndipo ndiye kalambulabwalo waposachedwa kwambiri wa tripeptideglutathione (GSH).Gamma glutamylcysteine ili ndi mayina ena ambiri, monga γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, kapena GGC mwachidule.
Gamma Glutamylcysteine ndi ufa wa crystalline woyera wokhala ndi mamolekyu a C8H14N2O5S ndipo ali ndi kulemera kwa 250.27.Nambala ya CAS pagululi ndi 686-58-8.
Gamma-glutamylcysteine VS Glutathione
Molekyu ya Gamma glutamylcysteine ndi kalambulabwalo wa glutathione.Imatha kulowa m'maselo ndikusandulika kukhala antioxidant yamphamvuyi ikakhala mkati mwa puloteni yachiwiri yotchedwa glutathione synthetase.Izi zitha kupereka mpumulo ku kupsinjika kwa okosijeni ngati zimathandizira ma cell omwe ali ndi GCL yosokonekera kuchira ndikuyambiranso kugwira ntchito bwino pankhondo yolimbana ndi ma free radicals omwe amawononga minofu yonse yathanzi pakapita nthawi!
Kuchulukirachulukira kwa gamma-glutamylcysteine (GGC) nthawi zambiri kumakhala kotsika chifukwa imakhudzidwa ndi glycine kupanga glutathione.Izi zimachitika mofulumira, monga GGC ili ndi theka la moyo wa mphindi 20 pamene ili mu cytoplasm.
Komabe, Oral ndi jekeseni supplementation ndi glutathione sangathe kuonjezera ma glutathione amtundu mwa anthu.Kuzungulira kwa glutathione sikungalowe m'maselo osasunthika ndipo iyenera kugawika koyamba kukhala zigawo zake zitatu za amino acid, glutamate, cysteine, ndi glycine.Kusiyana kwakukuluku kumatanthauza kuti pali mayendedwe osagonjetseka pakati pa ma extracellular ndi ma intracellular, omwe amaletsa kuphatikizika kulikonse kwa ma cell.Gamma-glutamylcysteine atha kukhala wosewera wamkulu pakutumiza GSH kudutsa zamoyo zambiri.
Gamma-glutamylcysteine VS NAC (N-acetylcysteine)
Gamma-Glutamylcysteine ndi mankhwala omwe amapereka ma cell ndi GGC, omwe amafunikira kuti apange Glutathione.Zina zowonjezera monga NAC kapena glutathione sizingachite izi konse.
Gamma-glutamylcysteine Mechanism of action
Kodi GGC imagwira ntchito bwanji?Makinawa ndi osavuta: amatha kukulitsa milingo ya glutathione mwachangu.Glutathione ndi amino acid yofunikira yomwe imagwira ntchito zambiri m'thupi ndikuteteza ku poizoni.Glutathione imagwira nawo ntchito ngati cofactor ya imodzi mwa ma enzymes atatu omwe amasintha leukotrienes kuti athandize kuchepetsa zizindikiro za mphumu, amathandizira kutulutsa zinthu zapoizoni m'maselo kuti athe kutulutsidwa ndi bile kukhala chopondapo kapena mkodzo, kukonza kuwonongeka kwa DNA komwe kumayambitsidwa ndi ma free radicals okhala ndi antioxidant katundu, imabweretsanso glutamine pambuyo pochita masewera olimbitsa thupi kumapangitsa kuti chitetezo cha mthupi chitetezeke pogwiritsa ntchito ma antibodies monga IgA (immunoglobulin A) omwe amatithandiza kutiteteza ku matenda opuma m'nyengo yozizira pamene timakhala otetezeka kwambiri-zonsezi pamene tikugwira ntchito zazikulu kwina kulikonse monga kulamulira kagayidwe kake!
Njira Yopangira Gamma-glutamylcysteine
Biological kupanga ndi nayonso mphamvu kwa zaka zambiri ndipo palibe amene akhala bwino malonda.Njira ya biocatalytic ya Gamma-glutamylcysteine inagulitsidwa bwino mu fakitale ya Cima Science.GGC tsopano ikupezeka ngati chowonjezera ku US pansi pa dzina lodziwika bwino la Glyteine ndi Continual-G.
Ubwino wa Gamma-glutamylcysteine
Gamma-glutamylcysteine imatsimikiziridwa kuti imakulitsa milingo ya glutathione m'kati mwa mphindi 90.Glutathione, chitetezo chachikulu cha thupi motsutsana ndi ma radicals aulere, amadziwika kuti amathandizira kuchepetsa kupsinjika kwa okosijeni kuchokera ku ma free radicals ndikuthandizira ntchito zosiyanasiyana zathupi kuphatikiza kutulutsa.
- Thandizani chiwindi, ubongo, ndi chitetezo cha mthupi
- Wamphamvu antioxidant ndi detoxifier
Glutathione ndiyofunikira kuti muchepetse thupi lanu komanso imathandizira kugwira ntchito kwa chiwindi, impso, thirakiti la GI, ndi matumbo.Glutathione imathandiza kwambiri kuti machitidwe a thupi azigwira ntchito bwino pothandizira njira zochotseratu poizoni kuphatikizapo zomwe zimapezeka m'magazi komanso ziwalo zazikulu monga impso, GI thirakiti, kapena matumbo. - Limbikitsani mphamvu, kuyang'ana, ndi kuika maganizo
- Zakudya zamasewera
Miyezo ya Glutathione imatha kukuthandizani kuti muchite bwino, kukhala wathanzi, ndikuchira mosavuta.Onetsetsani kuti mukuwonjezera glutathione kudzera muzakudya kapena zowonjezera kuti maselo amthupi azigwira ntchito bwino komanso azigwira bwino ntchito kuti athe kuchepetsa nthawi yochira pambuyo pochita masewera olimbitsa thupi.
Zotsatira za Gamma-glutamylcysteine
Gamma-glutamylcysteine ndi yatsopano pamsika wowonjezera, ndipo palibe zotsatira zoyipa zomwe zanenedwa pano.Iyenera kukhala yotetezeka kutengera malangizo a dokotala.
Mlingo wa Gamma-glutamylcysteine
Kuwunika kwachitetezo kwa mchere wa sodium wa GGC mu makoswe kwawonetsa kuti kuperekedwa pakamwa (gavage) GGC sikunali koopsa kwambiri pamlingo umodzi wa 2000 mg / kg, kuwonetsa kuti palibe zotsatira zoyipa zomwe zikutsatira mobwerezabwereza Mlingo watsiku ndi tsiku pamasiku 90.
