Malinga ndi Wikipedia, dzina la IUPAC la piperlongumine ndi 1--[(2E)-3-(3,4,5-Trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-imodzi, ndi zina. mawebusaiti amakonda kugwiritsa ntchito 5,6-dihydro-1-[(2E) -1-oxo-3- (3,4,5-trimethoxyphenyl) -2-propenyl] -2 (1H) -pyridinone.
Dzina la mankhwala a piperlongumine ndi lalitali kwambiri ndipo palibe anthu omwe angakumbukire, choncho ochita kafukufuku amagwiritsa ntchito piplatine kapena piperlongumine m'mabuku ambiri a sayansi.Ndipo 20069-09-4 ndi nambala yake yolembetsedwa ya CAS.
Dzina la malonda:Piperlongumine ufa
Dzina lina: Piplatin,PiperlongumineTingafinye, Piplatine, 5,6-Dihydro-1 - [(2E) -1-oxo-3- (3,4,5-trimethoxyphenyl) -2-propen-1-yl] -2(1H) -pyridinone,PPLGM , pippali ufa, Piper Longum Tingafinye
CAS NChiwerengero: 20069-09-4
Gwero la Botanical: Piper Longum Linn
Chiwerengero: 98% min
Zitsanzo Zaulere: Zilipo
Maonekedwe: ufa woyera wa crystalline
Ubwino: Anti-cancer, anti-kukalamba, senolytic
Alumali Moyo: 2 years
PiperlongumineAmapezeka makamaka ku Piper longum, chomera chochokera ku South Asia.India ndi China ndi mayiko awiri akuluakulu omwe amagulitsa malonda a Piper longum powders ndi zowonjezera pa Amazon ndi mawebusaiti ena a e-commerce.
Piper longum amadziwika kuti tsabola wautali kapena pippali ku India.Piper longum ili ndi alkaloids, amides, Lignans, Esters, mafuta osakhazikika, etc.
Chipatso cha Piper longum chakhala chikugwiritsidwa ntchito mu Ayurvedic system of Medicine ndi Traditional Chinese Medicines kwa nthawi yayitali.
Malangizo a Piperlongumine
Palibe ufa wochuluka wa piperlongumine pamsika pano.Ambiri mwa ogulitsa ndi makampani a reagent, ndipo malonda awo ndi ogwiritsira ntchito kafukufuku.Kuonjezera apo, kuchuluka kwawo nthawi zambiri kumakhala 10mg mpaka 500mg mu botolo laling'ono kwambiri.
Pali chiŵerengero akupanga a piper longum chomera, ndi specifications otchuka monga 4:1, 10:1, 20:1, etc.
Mankhwala azitsamba aku India okhala ndi piperlongumine amakhala ndi chiŵerengero chochotsa.Ndi mapiperlongumine angati mmenemo?Palibe amene akudziwa.Piperlongumine yokhazikika yokha kuchokera ku piper longumine ingayesedwe.
mawonekedwe ndi 98% min.
Ngati muli ndi mafunso, chonde musazengereze kutifunsa kuti mudziwe zambiri.
Piperlongumine solubility
Piperlongumine sisungunuka m'madzi.Kotero ngati mukufuna kugwiritsa ntchito mokwanira mankhwala owonjezera a piperlongumine, muyenera kupanga piperlongumine mu mawonekedwe a makapisozi m'malo mwa mapiritsi a piperlongumine kapena ufa.
Piperlongumine imasungunuka mu zosungunulira za organic monga ethanol, DMSO, ndi dimethylformamide (DMF).
Njira Yogwirira Ntchito ya Piperlongumine
Ubwino wa Piperlongumine
Monga mankhwala achikhalidwe omwe amagwiritsidwa ntchito ku China ndi India, chomera cha piper longum chimanenedwa kukhala chothandizira kupuma, komanso chabwino pakugaya bwino komanso chitetezo chamthupi.
Kwa piperlongumine yokha, anti-cancer ndi anti-kukalamba ndizofunikira ziwiri zazikulu.
Piperlongumine yoletsa kukalamba (senolytic)
Piperlongumine ndi novel senolytic wothandizira.Ngati mukufuna kudziwa momwe piperlongumine imagwirira ntchito poletsa kukalamba, muyenera kudziwa ma cell senescent poyamba.
Maselo a Senescent amagwira ntchito yofunika kwambiri pa matenda ambiri okhudzana ndi zaka.Titha kunena kuti maselo amthupi ndi omwe amayambitsa kukalamba.
Ndiye mmene kuthetsa matenda?Njira yosavuta ndiyo kupha maselo am'mimbawa!Maselo a Senescent ndi maselo osagwira ntchito amafuta omwe amaunjikana ndi zaka m'matenda ndi ziwalo zonse za thupi lanu.Piperlongumine imapangitsa apoptosis m'maselo a senescent ndikuwapha kudzera mu makina odziyimira pawokha a ROS.
Piperlongumine imatha kuchepetsa mapangidwe a maselo a senescent, mwa kusankha kuwononga maselo a senescent ndikutsitsimutsa thanzi lanu.Zimagwira ntchito bwino ndi zinthu zina zotsutsana ndi ukalamba, monga pterostilbene, resveratrol, fisetin, etc.
mayesero azachipatala a piperlongumine
Piperlongumine yaphunziridwa mozama mu chithandizo cha khansa kupita pamayesero azachipatala.Popeza lipoti loyamba lokhudzana ndi kugwiritsidwa ntchito kwake pa kafukufuku wa khansa (mu 2011) pafupifupi mapepala 80 asindikizidwa pasanathe zaka 10, koma kusiyana kudakalipo.Palibe maphunziro a metabolism a piperlongumine m'thupi la munthu.
Zotsatira zoyipa za Piperlongumine
Palibe zotsatira zoyipa zomwe zanenedwa pano.
