Nthawi zambiri timatha kukwaniritsa makasitomala athu olemekezeka ndi khalidwe lathu labwino kwambiri, mtengo wamtengo wapatali komanso chithandizo chabwino kwambiri chifukwa takhala akatswiri kwambiri komanso olimbikira kwambiri ndikuzichita m'njira yotsika mtengo ya Popular Design ku China CAS 1094 -61-7 99% NmnNicotinamide Mononucleotide Powder, Tikulandira makasitomala atsopano komanso achikale ochokera m'mitundu yonse yatsiku ndi tsiku kuti alankhule nafe kuti tigwirizane ndi mabizinesi am'tsogolo ndikupambana!
Nthawi zambiri timatha kukwaniritsa makasitomala athu olemekezeka ndi khalidwe lathu labwino kwambiri, mtengo wamtengo wapatali komanso chithandizo chabwino kwambiri chifukwa takhala odziwa zambiri komanso ogwira ntchito molimbika kwambiri ndikuzichita m'njira yotsika mtengo.China Nmn Powder, Whitening Zosakaniza, Zogulitsa ndi zothetsera zili ndi mbiri yabwino ndi mtengo wampikisano, chilengedwe chapadera, kutsogolera zochitika zamakampani.Kampaniyo imaumirira pa mfundo ya lingaliro la Win-win, yakhazikitsa maukonde otsatsa padziko lonse lapansi komanso maukonde otsatsa pambuyo pogulitsa.
Nicotinamide mononucleotide ufa wochuluka
Dzina la malonda:Nicotinamide mononucleotide ufa
Mawu ofanana ndi mawu: NMN,β-Nicotinamide Mononucleotide,beta-Nicotinamide Mononucleotide
Nambala ya CASChithunzi: 1094-61-7
Zofotokozera: 99% mphindi
Molecular Formula:C11H15N2O8P
Kulemera kwa Maselo334.221 g / mol
Phukusi: 1kg / thumba, 25kg / ng'oma
Kodi Nicotinamide Mononucleotide ndi chiyani?
Nicotinamide mononucleotide, yofupikitsidwa ngatiNMN, ili ndi mayina otsatirawa:
β-NMN, BETA-Nicotinamide Mononucleotide;
BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;
NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-PHOSPHATE;NICOTINAMIDE RIBOTIDE;
NICOTINAMIDE MONONUCLEOTIDE
NMN imapezeka m'zamoyo zosiyanasiyana kuphatikizapo anthu ndipo ndi yofunika kwambiri kuti thupi ligwire ntchito.NMN imagwiritsidwanso ntchito pambuyo popangidwanso ndi thupi, ndipo vitamini B3 muzakudya imathanso kupanga NMN.
Tisanamvetsetse nicotinamide mononucleotide, tiyenera kudziwa kuti ndi chiyani.Nicotinamide mononucleotide (NMN) ndiye kalambulabwalo wofunikira wa NAD+, ndipo NAD+ ndi njira yofunika kwambiri yokonzanso ma cell mwa anthu.Pamene anthu ali mu makanda ndi ana aang'ono, kukula ndi chitukuko chawo chimakhala chofulumira kwambiri, ndipo ndi kukula kwa msinkhu, ntchito ya thupi la munthu imachepa pang'onopang'ono.Chitsanzo chosavuta chili ngati chakale;mudzachititsidwa khungu mwangozi.Mabampuwo anagwetsedwa, ndipo choipitsitsacho, anavulala kwambiri.M'kati mwa ukalamba wa maselo aumunthu, kuchuluka kwa NAD + kudzachepetsedwa kwambiri poyerekeza ndi zakale chifukwa cha kagayidwe kachakudya komanso thupi lenilenilo.
Nicotinamide mononucleotide ndi gawo lofunikira pakukonzanso kwaumunthu.Asayansi padziko lonse lapansi apeza kuti nicotinamide mononucleotide imakhudza ukalamba.Pakufufuza mozama, chinsinsi cha nicotinamide mononucleotide ndikuti ndiye kalambulabwalo wa NAD +, yomwe idzasinthe Kwa NAD +, kuwonjezera chinthu chokonzanso ma cell m'maselo amunthu, kukana kukalamba, ndikukhala ndi mwayi woyambitsanso ntchito yokulirapo. cell, yomwe ndi ntchito yowonjezera moyo wa nicotinamide mononucleotide.
Nicotinamide mononucleotide mwachilengedwe imakhalapo m'maselo aliwonse amthupi lathu ndipo ndi gawo lofunikira pakudzikonza kwa thupi.Ndi metabolite yosungira NAD + biosynthesis wamba, ndipo chinthuchi chimatha kuwongolera physiology pakuyenda kwa thupi, komanso matenda enaake.Zimagwira ntchito yofunika kwambiri m'maselo.
Zowonjezera zomwe zili ndi NMN
Pali zambiri zowonjezera za NMN zomwe zikugulitsidwa pano.Ena ndi otchuka pakati pa ogwiritsa ntchito mapeto, monga NMN Pure, Ultra NMN, etc. pa Amazon ndi masitolo ena a pa intaneti.
Mafomu ena ali ndi NNN yokha, ndipo ena ali pamodzi ndi zosakaniza zina zotsutsana ndi ukalamba, monga resveratrol, pterostilbene, zomwe zimawonetsa mizu, ndi zina zotero.
Mafomu onse a makapisozi ndi mapiritsi alipo, pansipa pali zina zowonjezera za NMN zochokera ku zolemba zina za NMN:
125mg ikuwoneka ngati mlingo wotchuka wa zowonjezera zambiri za NMN, ngakhale kuti ena amalemba 260mg pa capsule pa malemba awo ndi kukula kwa makapisozi a 2 kapena mapiritsi tsiku lililonse.Palibe mlingo wovomerezeka wovomerezeka pakadali pano.
Njira yogwiritsira ntchito nicotinamide mononucleotide
Nicotinamide mononucleotide imasinthidwa kukhala "nicotinamide adenine dinucleotide (NAD)" chinthu chofunikira pa metabolism yamphamvu m'thupi.Poyesa mbewa, zidatsimikiziridwa kuti nicotinamide mononucleotide imatha kuyambitsa jini yotchedwa acetylase m'thupi, motero imakhala ndi zotsatira monga kutalikitsa moyo komanso kuchiza matenda a shuga.NAD ndi chinthu chomwe chingapangidwe ndi thupi la munthu.Kafukufuku wasonyeza kuti NAD zomwe zili m'thupi zimachepa ndi zaka.
Kuwonjezeka kwa kutupa komwe kumayenderana ndi ukalamba kumatha kusokoneza mphamvu ya thupi kupanga NMN, zomwe zimapangitsa kuchepa kwa NAD.
NMN ndi kalambulabwalo wa coenzyme NAD + yovuta m'thupi.Nicotinamide mononucleotide ndi gawo lofunikira pakupanga mphamvu zama cell amunthu, ndipo imakhudzidwa ndi kaphatikizidwe ka intracellular NAD+ (nicotinamide adenine dinucleotide, coenzyme yosinthira mphamvu zama cell).
NMN idadziwika kuti ndi chinthu choyambirira padziko lapansi chomwe chimatsimikiziridwa ndi kafukufuku wozama wasayansi kuti asinthe ndikuchedwetsa kukalamba ndikutalikitsa moyo.
Mu 2017, kafukufuku wasonyeza kuti NMN ikhoza kuchiza NR ndi NMN ataxia, ndipo NR sichisintha ntchito ya SIRT3 kapena kupititsa patsogolo ntchito ya mtima.
Kupereka kwa NAD + sikudzakhazikika - kupitilira kudyedwa ndikuwonjezeredwa, ndipo dziwe lonse la NAD + limatembenuka 2-4 pa tsiku.
Kuzungulira uku kumachitika kudzera m'njira zokonzanso, momwe enzyme Nampt imathandizira NAM kupita ku NMN kenako imapangidwira ku NAD +.Namp ndi njira yochepetsera liwiro pakusodza.
Nicotinamide Mononucleotide VS.Nicotinamide Riboside
Masiku ano, dziko lapansi ndi lolemera mu kafukufuku wosiyanasiyana ndi NR, ndipo kuyesa kwa thupi la munthu kumapangitsa zotsatira za NR pazidziwitso zamaganizo kuposa NMN.Komabe, kafukufuku wasonyeza kuti NR imayamba kugwira ntchito m'thupi la munthu ndipo ikufunikabe kudziwa kwakanthawi.Chinsinsi ndichoti onse a NR ndi NMN ndi otsogola a NAD +, pomwe Nicotinamide Riboside (NR) ndi kalambulabwalo wa NMN ndi NAD +, kotero NR ikusintha.Zimatenga kanthawi kuti NAD + ichitike.Poyerekeza ndi zotsatira zaposachedwa za NMN, mphindi 15 za NR ndi kusiyana kwakukulu.
Zitha kuwoneka kuchokera pa chithunzi pamwambapa kuti NAMPT ndi chinthu chofunikira kwambiri cholepheretsa kubadwa kwa NMN.Pamene msinkhu ukuwonjezeka, osati thupi laumunthu silikufuna kukhala laling'ono, koma ntchito ya enzyme ya NAMPT imachepa pamene mphamvu ndi zakudya zimaperekedwa.Pamene kuzungulira kwa NAM kumachepetsedwa, katundu wa NAD + amachepetsedwa mwachilengedwe.
NR ikhoza kusinthidwa kukhala NMN kapena ku NAM, malingana ndi ntchito ya enzyme ya Nrk1 kuti mudziwe kuti ndi chiyani chomwe chili ndi khalidwe lomwelo la NR chidzatulutsa zambiri.Ngati isinthidwa kukhala NAM, imaletsedwanso ndi enzyme ya NAMPT.Poyerekeza ndi machitidwe achindunji a NMN kuti apange NAD +, zotsatira za kuchuluka kofanana kwa NR mwachiwonekere zimafooka kwambiri.
Bwanji osatenga NAD +?
NAD + siingatengedwe mwachindunji m'maselo ndi kayendetsedwe ka pakamwa chifukwa cha kulemera kwake kwa maselo.Kuphatikizika kwa NAD + kumangopezeka ndikulowetsa kalozera kakang'ono ka molekyulu NAD +.
Komabe, NMN imatha kupangidwa kukhala zinthu zosiyanasiyana, zomwe zimatha kukhala makapisozi, mapiritsi, ngakhale ma granules chifukwa cha kusungunuka kwake.Kusungunuka kwa NMN m'madzi ndi 35mg/ml.
M'lingaliro ili, NMN ndiyabwino kwambiri kuposa NAD+, komanso yolunjika kuposa nicotinamide riboside.
Nicotinamide Mononucleotide amapindula
Zotsatira zazikulu za NMN ndi izi:
- anti-oxidation
- Kuchepetsa kuchepa kwa thupi
- Kukonza DNA
- Thandizani zotsatira za neuroprotective
- Kupititsa patsogolo ntchito ya mtima ndikuteteza mtima
- Sinthani mawonekedwe a odwala Alzheimer's
Chodziwika kwambiri cha NMN ndikuti imatha kusintha ukalamba ndikutalikitsa moyo.
Zotsatira za Nicotinamide Mononucleotide
Popeza kuti NMN pakali pano ikungoyesa zinyama, mayesero akuluakulu a anthu sanayambe, choncho zotsatira zake zomwe zingathe kutsimikiziridwa sizikudziwikabe.Komabe, molingana ndi momwe NMN imagwirira ntchito, zitha kunenedwa kuti odwala khansa sayenera kutenga momwe angathere.Chifukwa kusintha kwa NMN kumalimbikitsa kupanga NAD +, pomwe ma cell a khansa amasintha kuti azichita zinthu pang'onopang'ono, kuchuluka kwa metabolism kumatha kuyambitsa kufalikira kwa maselo ena a khansa.
Mukamagwiritsa ntchito nicotinamide nucleoside supplements monga NMN, masewera olimbitsa thupi amatha kukhudzidwa.Mu mbewa, mbewa zomwe zidabayidwa ndi NAD + zowonjezera zidawonetsa magwiridwe antchito ochepa kuposa gulu lawo lowongolera.
