I-Adenosine yi-nucleoside ye-purine eyenziwe yi-molecule ye-adenine edityaniswe kwi-molecule ye-sugar ribose (i-ribofuranose) i-moiety ngokusebenzisa i-β-N9-glycosidic bond.I-Adenosine ifumaneka ngokubanzi kwindalo kwaye idlala indima ebalulekileyo kwiinkqubo ze-biochemical, ezifana nokudluliswa kwamandla - njenge-adenosine triphosphate (ATP) kunye ne-adenosine diphosphate (ADP) - kunye nokuguqulwa komqondiso njenge-cyclic adenosine monophosphate (cAMP).Ikwayi-neuromodulator, ekholelwa ukuba idlala indima ekukhuthazeni ukulala kunye nokucinezela ukuvuswa.I-Adenosine nayo idlala indima ekulawuleni ukuhamba kwegazi kumalungu ahlukeneyo nge-vasodilation.
Igama lemveliso:Adenosine
Elinye Igama:Adenine riboside
Inombolo yeCAS: 58-61-7
Ifomula yeemolekyuli: C10H13N5O4
Ubunzima bemolekyuli: 267.24
EINECS NO.: 200-389-9
Indawo yokunyibilika: 234-236ºC
Inkcazo: 99% ~ 102% yi-HPLC
Imbonakalo:I powder emhlophe enevumba elibonakalayo kunye nencasa
Isimo se-GMO:GMO Mahala
Ukupakisha: kwi-25kgs fiber drums
Ugcino: Gcina isikhongozeli singavulwanga kwindawo epholileyo neyomileyo, Zigcine kude nokukhanya okuqinileyo
Ubomi beShelf: iinyanga ezingama-24 ukusuka kumhla wokuvelisa
Umsebenzi:
-I-Adenosine yi-nucleoside engapheliyo kwiiseli zomntu ngokuthe ngqo kwi-myocardium nge-phosphorylation ivelisa i-adenylate ebandakanyekayo kwi-metabolism yamandla e-myocardial.I-Adenosine nayo iya kukwandiswa kwemithambo ye-coronary, inyusa ukuhamba kwegazi.
-I-Adenosine idlala indima yomzimba kwi-cardiovascular system kunye neenkqubo ezininzi kunye nemibutho yomzimba.I-Adenosine isetyenziswe kwi-synthesis adenosine triphosphate, i-adenosine (ATP), i-adenine, i-adenosine, i-vidarabine ebalulekileyo phakathi.
Inkqubo
I-Adenosine idlala indima ebalulekileyo kwi-biochemistry, kuquka i-adenosine triphosphate (ATP) okanye i-adeno-bisphosphate (ADP) uhlobo lokudluliselwa kwamandla, okanye kwi-cyclic adenosine monophosphate (cAMP) yokuhanjiswa kwesignali kunye nokunye.Ukongezelela, i-adenosine yi-neurotransmitter evimbelayo (i-neurotransmitter ye-inhibitory), inokukhuthaza ukulala.
Uphando lwezifundo
NgoDisemba 23 “yendalo – Medicine” (Nature Medicine) uphononongo olutsha lubonisa ukuba ikhompawundi iya kusinceda ukuba sithomalalise ingqondo yokulala kunye nezinye izifo zengqondo Isifo sikaParkinson Ukuvuselela ubuchopho obunzulu bempumelelo kubalulekile.Olu pho nonongo lubonisa ukuba: ingqondo eleleyo ingakhokelela kwi-compound - i-Adenosine yimpembelelo yengqondo enzulu (DBS) yesitshixo.Itekhnoloji yonyango lwesifo sikaParkinson kunye nezigulana ezinokungcangcazela kakhulu, le ndlela nayo yazama ukunyanga ukudakumba okukhulu.
