Dihydromyricetin 98%

I-Dihydromyricetin, eyaziwa ngokuba yi-Ampelopsin, yi-flavanonol, uhlobo lwe-flavonoid.Ifumaneka kwiintlobo ze-Ampelopsis japonica, megalophylla, kunye ne-grossedentata;Cercidiphyllum japonicum;Hovenia dulcis;iRhododendron cinnabarin;ezinye iintlobo zePinus;kunye nezinye iintlobo zeCedrus, kunye neSalix sachalinensis.

I-Hovenia dulcis isetyenziswe kumayeza emveli aseTshayina ukunyanga umkhuhlane, usulelo lwe-parasitic, njenge-laxative, kunye nonyango lwezifo zesibindi, kunye nonyango lwe-hangover.Iindlela ziye zaphuhliswa ukukhupha i-ampelopsin kuyo kwizikali ezinkulu.

Kwindlela yezigulane ezingamashumi amathandathu ezinesifo sesibindi esinamafutha i-dihydromyricetin iphuculwe i-glucose kunye ne-lipid metabolism kunye nemiphumo echasene ne-anti-inflammatory eluncedo.I-Dihydromyricetin ine-antioxidant, i-alcohol anti-intoxicant, i-anti-inflammatory kunye ne-anticancer properties, iyanceda kwakhona ukukhupha i-radicals yamahhala, ukukhusela ukusebenza kwesibindi kunye nokulawula iswekile yegazi kunye namafutha egazi.Isicatshulwa seti yediliya i-dihydromyricetin isetyenziswa ikakhulu ekukhuseleni isibindi kunye nezongezo ezinxilisayo ezichasene ne-alcohol kunye nemveliso yokunakekelwa kwesikhumba. Iti yediliya, ikwabizwa ngokuba yiCany tea okanye i-Ampelopsin.Dihydromyricetin itsalwa kwisiqu esincinci kunye negqabi leti yeCany (Ampelopsin) Abaphandi babonisa kuneti yomdiliya inokuphelisa ukudumba, ukhohlokhohlo oluxutyiweyo kunye ne-antitussives, ikwanefuthe eliqinileyo lokuthintela kwiibhaktheriya eziqhelekileyo inokufumaneka ekutyeni.Ezinye ze-flavonoids, umzekelo i-Ampelopsin kunye ne-Dihydromyricetin, zizithako eziphambili ezisebenzayo kwiti yomdiliya, ene-MIC ephantse ifane. kunye ne-MBC ngokuthelekisa kunye ne-berberine, kwaye ibe nomsebenzi ophezulu wokutshabalalisa ngokukhululekileyo uhluka phakathi kwe-73.3 ~ 91.5%.Kwakhona kunokunciphisa umonakalo we-oxidative emzimbeni, ukuchasana nokuguga, ukunciphisa i-deformation kunye ne-tissue necrosis yesibindi sesilwanyana.I-Dihydromyricetin nayo inamandla ekuphakamiseni i-alcohol poisoning, ukukhusela i-AFL, inqanda ukuwohloka kweeseli zesibindi, ukunciphisa iziganeko zomhlaza wesibindi. .Kule meko, i-Dihydromyricetin ithathwa njengemveliso elungileyo yokuphucula umsebenzi we-SOD, ukukhusela isibindi kunye nokususa ukungathobeki.
I-Dihydromyricetin ngoku ingene kwizilingo zeklinikhi njengeklasi yamachiza amatsha xa umphandi we-Dihydromyricetin efumene impumelelo enkulu kwintsimi ye-anti-leukemia kunye neyeza lomhlaza we-Nasopharyngeal.

Igama leMveliso: Dihydromyricetin 98%

Inkcazo:I-98% yi-HPLC

Umthombo wezityalo:Hovenia dulcis

Inombolo yeCAS: 200-001-8

Indawo Yezityalo Ezisetyenzisiweyo:Ixolo

Umbala:umgubo omhlophe ococekileyo onevumba elibonakalayo kunye nencasa

Isimo se-GMO:GMO Mahala

Ukupakisha: kwi-25kgs fiber drums

Ugcino: Gcina isikhongozeli singavulwanga kwindawo epholileyo neyomileyo, Zigcine kude nokukhanya okuqinileyo

Ubomi beShelf: iinyanga ezingama-24 ukusuka kumhla wokuvelisa

Abantu abaninzi abasela utywala bayayazi intlungu ye-hangover: intloko ebuhlungu, isiyezi, ukudinwa, isicaphucaphu, ukungakhululeki kwesisu, ukozela, ukubila, ukunxanwa, nokuqonda.

Nasi isongezelelo sokutya esinokunciphisa kakhulu i-hangover yakho, ingakuvumeli nje ukuba uzive ubuhle bewayini, ivodka, irum, newhiskey kodwa ungoyiki ukungonwabi okubangelwa kukusela kakhulu.

Le yi-Dihydromyricetin powder (DHM), isipho sendalo esivela kwisityalo samandulo sasempuma seti yomdiliya.

Yintoni i-dihydromyricetin (DHM)?

I-Dihydromyricetin, eyaziwa ngokuba yi-snake glucose, yi-flavonoid ethileikhutshwe kwiti yomdiliyaokanye Hovenia Dulcis.

Ifomula yolwakhiwo lweDHM:

Iimpawu zomzimba kunye neekhemikhali ze-DHM:

Ikristale yenaliti emhlophe, enyibilikayo kumanzi ashushu, i-ethanol eshushu, kunye ne-acetone, ikwanyibilika kwi-ethanol kunye ne-methanol, kodwa kunqabile ukunyibilika kwi-ethyl acetate, enganyibiliki kwi-chloroform, i-petroleum ether.Uphononongo lweMicroherb luxelele ukuba i-dihydromyricetin inozinzo olugqwesileyo lobushushu, kodwa i-oxidation engenakubuyiseka kwenzeka xa i-dihydromyricetin ingaphezulu kwe-100 °C.I-DHM izinzile phantsi kweemeko ezingathathi hlangothi kunye ne-acidic.

Ezi zinto zineziphumo ezininzi ezizodwa ezifana nokukhupha i-radicals yamahhala, i-anti-oxidation, i-anti-thrombosis, i-anti-tumor, i-anti-inflammatory, njalo njalo.Ibizwa ngokuba yodwa kuba inezi mpawu zilandelayo ukongeza kwiimpawu eziqhelekileyo ze-flavonoids:

1. Iiflavonoids ezixhaphakileyo azinyibiliki emanzini, zinyibilika kwi-ethanol (utywala), kwaye i-DHM inyibilika ngokulula emanzini ashushu, okuthetha ukuba i-DHM kwiti yomdiliya inokutsalwa ngamanzi abilayo kwaye isebenze ngakumbi;
2. Ukongeza kwisenzo se-flavonoids jikelele, i-dihydromyricetin inemisebenzi yokunciphisa utywala, ukuthintela isibindi esinxilisayo, kunye nesibindi esinamafutha, ukuvimbela ukuwohloka kweeseli zesibindi, kunye nokunciphisa iziganeko zomhlaza wesibindi;yimveliso efanelekileyo yokukhusela isibindi kunye nokukhusela isibindi kunye ne-hangover.
3. I-Dihydromyricetin inobunzima obuphantsi be-molecular (320), ekulula ukudlula kwi-barrier-brain barrier kwaye iqala ngokukhawuleza.

Yintoni isicatshulwa seti yomdiliya?

Iti yomdiliya, eyaziwa ngokuba yiti yequnube, ngumdiliya wasendle wohlobo lweVitis.Ayisiyo kuphela isiselo esicocekileyo sendalo esiluhlaza kodwa kunye neti eneempawu ezinamandla zonyango.Isityebi kwi-flavonoids, i-amino acids, iivithamini, kunye nezinto ezibalulekileyo zokulandelela.Inemisebenzi yokuthambisa imithambo yegazi, inzalo kunye ne-anti-inflammatory, kunye nokusela ixesha elide kunokuphelisa impilo engaphantsi komzimba womntu.Ibiyimbali yokusela kwabantu kangangamawaka eminyaka, kwaye ibilinywa kangangamakhulu eminyaka.Kangangamawaka eminyaka, yayiyeyona nto ithandwayo kwiinkosana zezidwangube, kwaye yayiyintliziyo yomfama wasendle.

Ngokwezondlo kunye neengcali zeeti, itiyi yeediliya isisityebi kwi-phytonutrients.Phakathi kwabo, i-dihydromyricetin inokucoca ubushushu obugqwesileyo kunye ne-detoxification, i-dilating throat, i-anti-bacterial and anti-inflammatory, i-anti-influenza i-virus ye-hepatitis B kwaye incedisa "ezintathu eziphezulu" zokukhusela kunye nokunyangwa kwezifo zenhliziyo kunye ne-cerebrovascular.

Isicatshulwa seti yeVine VS Hovenia Dulcis isicatshulwa

I-Hovenia Dulcis ayingowona mthombo uphambili we-dihydromyricetin kuba iphantsi kumxholo kwaye iphezulu kwiindleko.Iti yeediliya lolona khetho lungcono.

I-DHM ibuphelisa njani ubunxila kunye ne-hangover?

I-DHM inokuphucula isakhono somzimba wakho sokuphula utywala, ukuze ungabi nayo inkungu yasekuseni kunye nobuthongo xa uvuka.

Yintoni ubudlelwane phakathi kotywala obunxilisayo kunye nemvakalelo yakho yosuku lwesibini?

Iziko elibizwa ngokuba "Iziko leSizwe lokusetyenziswa kakubi kotywala kunye noTywala" linemibuzo emininzi enesihloko esithi < Alcohol Metabolism: A Update>.

Uphononongo luchaza eyona nkqubo iphambili yokuqhekeka kotywala.Silapha ukuze sishwankathele iindawo eziyimfuneko kuwe.

Ii-enzymes ezimbini-i-alcohol dehydrogenase (ADH) kunye ne-acetaldehyde dehydrogenase (ALDH)-inceda umzimba wakho ukuba uphule utywala.

Xa uqala ukusela, i-ADH iphula utywala kwi-acetaldehyde, into enetyhefu kakhulu kunye ne-carcinogenic.

Emva koko, i-ALDH iphinda idibanise i-acetaldehyde ibe yimveliso ene-asidi ebizwa ngokuba yi-acetate, ethi emva koko iphulwe emanzini kwaye ikhutshwe ngokukhuselekileyo emzimbeni wakho.

Ngoko kutheni uziva ungakhululekanga kusasa emva kokusela ubusuku bewayini?

Xa usela ngaphezu komlinganiselo wesibindi esinokwaphulwa, ityhefu ebangelwa zezi tywala iya kufumba kwaye ibeke uxinzelelo olukhulu emzimbeni wakho.

Ixesha elide le tyhefu isemzimbeni wakho, ngakumbi uya kuziva ngosuku olulandelayo ngaphambi kwemetabolism kunye nokukhupha okukhuselekileyo.

Ngamanye amazwi, izinto ezinobuthi ezinde ziyavezwa emzimbeni wakho kwaye zinokonyusa i-sequelae yokusela.

I-DHM iza kuhlangula!

Le flavonoid enamandla inceda ukukhusela isibindi (kunye neemvakalelo zakho ngosuku olulandelayo) ngokukhawulezisa imetabolism yotywala.

Sazi njani?

Uphononongo lubonise ukuba iti yeVine isicatshulwa i-DHM inokunyusa ukusebenza kwe-ADH kunye ne-ALDH esibindini, ivumela umzimba ukuba udibanise kwaye ukhuphe utywala kunye netyhefu ngokukhawuleza.

Emva koko uvuka kwaye uzive uhlaziyekile kwaye ulungele usuku olutsha!

I-DHM kunye notywala buchaphazela njani ingqondo?

Utywala buneziphumo ezininzi kwingqondo.

Ikhefu lokuqala liphula ibhalansi ebuthathaka phakathi kwee-neurotransmitters ezimbini:

i-gamma-aminobutyric acid(GABA) kunye ne-glutamate.

Iingcebiso:

Yintoni iGABA?

I-GABA yinto yendalo engeyiyo iprotheni ye-amino acid eyi-neurotransmitter ebalulekileyo ye-inhibitory kwi-mammalian central nervous system.Idlala indima ebalulekileyo kwi-cortex ye-cerebral yomntu, i-hippocampus, i-thalamus, i-basal ganglia kunye ne-cerebellum, kwaye inefuthe elilawulayo kwimisebenzi eyahlukeneyo yomzimba.Oko kukuthi, xa ukusilela komzimba kweGABA, kuya kuvelisa ixhala, ixhala, ukudinwa, ukuxhalaba kunye nezinye iimvakalelo.

Njenge-neurotransmitter ye-inhibitory, i-GABA inokuthintela ngokufanelekileyo ukukhutshwa ngokugqithiseleyo kwee-neurotransmitters ezinomdla ezifana ne-dopamine, eshiya abantu bekwimeko yokuphumla, ukunciphisa uxinzelelo lwegazi, ukubetha kwentliziyo, kunye nokuzola.

Ngamanye amazwi, iGABA yinto ephumza iingqondo nemizimba yabantu.

Xa utywala bubophelela kwi-GABA receptor, yenza ukuba i-GABA receptor isebenze, ibangele iqondo eliphezulu lokuphumla, ukunciphisa ukuvinjelwa, ukungaqondakali, kunye nokulahlekelwa kolawulo lwemoto.

Oku kuziphatha kwenza ingqondo icinge ukuba kukho i-GABA eninzi kwinkqubo kunesiqhelo.

Emva koko umzimba wakho uzama ukunciphisa umxholo we-GABA ukubuyisela ibhalansi.

Kodwa ngentsasa elandelayo xa utywala bushiya iodolo yakho, unokufumana isiphumo esiphinda siphinde sibangele unxunguphalo, ubunzima bokulala, kunye nokungabikho koxinzelelo.

I-DHM iqinisekisa ukuba utywala buchaphazela ingqondo ye-GABA receptors kancinane, ngoko ke le ndlela yokusabela ayenzeki kwaye awuyi kufumana iimpawu zokubuyela emva okanye ukuxhoma ngosuku olulandelayo.

I-DHM inokukhawulezisa ukubola kwe-acetaldehyde kwaye ikhusele isibindi.

I-Dihydromyricetin nayo inzima ukuxhasa isibindi ukuphula i-acetaldehyde enetyhefu ngokukhawuleza.

Xa usela utywala, umzimba uyabuqhekeza ube yimichiza emincinci de zonke iimveliso eziphumayo ziphele.

Noko ke, enye yeekhompawundi ibizwa ngokuba yi<em>acetaldehyde, enetyhefu ephindwe kangama-20 kunotywala.

Uxinzelelo oluphezulu lwe-acetaldehyde kwinkqubo yakho lunokubangela iimpawu ezingathandekiyo kwaye zonyuse iimpawu ze-hangover ngosuku olulandelayo.

Xa umzimba wakho ugcwele i-acetaldehyde, isibindi sakho sinokuyisusa ngokukhawuleza.Nangona kunjalo, i-DHM inokunceda umzimba wakho uphule i-acetaldehyde ngokukhawuleza, ukuze ubuyele kwisiqhelo ngokukhawuleza.

Ndiyithathe nini, phambi okanye emva kokusela?

Xa uthatha i-dihydromyricetin, kuxhomekeke kumsebenzi ozama ukuwufeza.

Ngoko ke, umzekelo, abaphandi bafumanisa ukuba ukuthatha umthamo omkhulu ngaphambi kokusela utywala kunciphisa izinga lotywala egazini nge-55%.

Nangona kunjalo, kubantu abaninzi, sincoma ukuyenza ngokukhawuleza emva kokusela, eyona ndlela ibalaseleyo yokunciphisa iimpawu ze-hangover ezivame ukuvakala ngosuku olulandelayo.

Ukuthatha i-DHM emva kokusela utywala kunokuthintela i-GABA rebound effect, ikuvuse rhoqo ezinzulwini zobusuku, okanye ixhala ngawe ngosuku olulandelayo.

Ke ukuthatha iDHM kwangoko emva kokusela kuthetha ukuba iziphumo ezibi zotywala ziya kuncipha.

Ngaba i-dihydromyricetin iyasebenza kwaye yeyiphi idosi efanelekileyo?

Ewe.Kukho ubungqina obaneleyo besayensi bokubonisa ukuba i-dihydromyricetin iyasebenza ekunciphiseni imiphumo yetyhefu kunye nokunciphisa i-hangover kunye nokuxhasa isibindi.

Owona mbuzo ngulo, leliphi elona thamo lifanelekileyo?

Isicatshulwa sotywala se-125 mg / kg ubunzima bomzimba sisetyenzisiwe kwiigundane ezikwaziyo, okuguqulela kumlinganiselo oqikelelwayo womntu we-9-9.3 mg / lbs ubunzima bomntu,

ilingana ne:

1, 400mg umntu 150lb

2, 800mg umntu 200lb

3, 1200mg kubantu abangama-250lb

Ezi ziidosi eziqikelelweyo zomntu ngokusekwe kuphononongo lweempuku.

Nangona kunjalo, ezi zinto zilandelayo kufuneka ziqwalaselwe xa usebenzisa idosi:

Inani leziselo ezinxilisayo owakhe watya

Utywala obukwisiselo buphelile

Usela ngokukhawuleza kangakanani?

Ngaba ukhe watya?

Ngokwenyani, kukwaxhomekeke kwinto ofuna ukuyiphumeza nge-DHM kuba idosi efunekayo yokunciphisa ityhefu iphezulu kakhulu kunethamo emva kokusela ukuphelisa i-hangover.

Izongezo ezinedihydromyricetin:

Imisebenzi:

I-1) Ukucoca i-radical yamahhala emzimbeni kunye ne-antioxidation: Isicatshulwa seti yediliya sinokusebenza ngokufanelekileyo phantsi kwe-lipid peroxidation.Inokuthintela umonakalo oxidative we-antioxidase emzimbeni obangelwa yi-radical yamahhala.Emva koko inokuphucula ukuxhathisa kwe-oxidation yomzimba womntu;
2)Antibiotic Action: Isicatshulwa seti yomdiliya sinesenzo esinamandla sokuthintela i-staphylococcus aureus kunye ne-Bacillus subtilis.Ikwanesenzo sokuthintela iAspergillus flavus, Aspergillus niger, penicillium kunye neAlternaria.I-Dihydromyricetin ine-inhibitory action ye-Staphylococcus aureus, i-Staphylococcus aureus (S. aureus) kunye ne-Pseudomonas aeruginosa.
3) Ukukhusela isibindi: I-Dihydromyricetin inesenzo esinamandla sokuthintela ukunyuka kwe-ALT kunye ne-AST kwi-Serum yegazi.Inokwehlisa i-bilirubin iyonke kwiserum yegazi.Ke inesenzo esinamandla sokuthoba i-aminotransferase kunye ne-jaundice.Isicatshulwa seti yomdiliya sinokunqanda i-fibrosis yesibindi kwimpuku.
I-4) Ukunciphisa amanqanaba eswekile yegazi kunye namafutha egazi: I-Dihydromyricetin inokunciphisa amanqanaba egazi kwimouse.Inokunciphisa umonakalo kwiiseli zesibindi ezibangelwa ngamanqanaba aphezulu e-fat fat kunye nokuphucula amandla e-antioxidation.Kwangaxeshanye, inokwehlisa amanqanaba aphezulu eswekile yegazi.
I-5) Ukudumba kwe-Anti: Isicatshulwa seti yomdiliya sinokuthintela ngokufanelekileyo ukudumba kwepina yempuku okubangelwa yixylene.Inokuthi ithintele impendulo yokujija kwimpuku ebangelwa yi-acetic acid.
I-6) I-Anti-tumor: Isicatshulwa seti yediliya sinokuzibamba okusebenzayo kwi-cell proliferation yezinye iiseli zethumba.

Usetyenziso:

Iimveliso zonyango:

I-Dihydromyricetin isetyenziswa ngokubanzi kwizinto ezifana ne-anti-inflammatory, antitussive, expectorant, analgesic, i-antibacterial medicinal 1700ppm okanye ngaphezulu.Iipilisi, iipilisi, iigranules, njl.

Iimveliso zokhathalelo lwempilo:

Khusela isibindi, umphumo we-hangover.Ukukhawulezisa ukubola kwe-ethanol metabolite acetaldehyde.100-800ppm

Ukunciphisa iswekile yegazi, i-lipids yegazi 150-200ppm

Antioxidant, free radical scavenging 400ppm

I-DMY inokuthintela kakhulu ukubunjwa kwe-MDA kwioli kunye namafutha, kwaye iye yaphucula umsebenzi we-antioxidant ngobunyulu;inefuthe elinamandla le-antioxidant kwioli yezilwanyana kunye neoli yemifuno.

Ababoneleli ngemathiriyeli ekrwada abaliqela njengesiqinisekiso sobonelelo.AMaziko eNtsebenziswano awomeleleyo ukuxhasaIziko lebhotani/Iziko leMicrobiology/Iziko leSayensi neTekhnoloji/Dyunivesithi