Osthole 98%

I-Fructus cnidii (iCommon Cnidium) sisityalo sonyaka, ubude be-30-80cm.Igqabi leFructus cnidii liyatshintshana, i-compundumbel inflorescence.Cremocarp, ellipsoidal, 2-4 mm ubude, malunga ne-2 mm ububanzi.Ngaphandle greyish-tyheli okanye greyish-brown;kunye ne-2 stylopods egobileyo encotsheni, kwaye ngamanye amaxesha kunye nesikhondo sesiqhamo esihle kwisiseko.Umphezulu weDorsal we-mericarps onemiqolo emihlanu ebhityileyo kunye nelongitudinal, umphezulu we-commissural owenziwe mcaba, kunye neembambo ezimbini ezimdaka kunye nezinyuswe kancinci.Fructus cnidii's pericarp lax kwaye eethe-ethe, ikhuhla lula, imbewu encinci, greyish-brown kwaye inamafutha.Ivumba, ivumba;incasa, ihlaba, ipholile kwaye ndindisholo.

I-Osthol, eyaziwa ngokuba yi-methoxyparsley, i-parsley methyl ether, yi-coumarin compounds, kwi-ambrella yesityalo se-osthol iphezulu, ebizwa ngokuba yi-osthol.Ngomnyaka we-1909, uHerzog noKrohn baqala ukufumana i-osthol edibeneyo kwiingcambu ze-ambrella plant europhus.Okwangoku, ifumaneka ngokubanzi kwizityalo, ikakhulukazi kwi-umbelliferae kunye ne-rutaceae, kunye nakwi-compositae ezimbalwa kunye nemifuno.
I-cnidium cnidium yorhwebo itsalwa ikakhulu kwiziqhamo ezomisiweyo nezivuthiweyo ze-cnidium cnidium.I-Cnidium isasazwa kakhulu kwi-guangxi, i-jiangsu, i-anhui, i-shandong, i-hebei, njl.

Igama lemveliso:Osthole 98%

Inkcazo:I-98% yi-HPLC

Igama lesiLatini:C.monnieri (L.) Cusson

Umthombo weBotanic:ISiqhamo seCnidium esiQhelekileyo

Inombolo yeCAS: 484-12-8

Inxalenye yesityalo esetyenzisiweyo: Imbewu

Umbala:Omdaka ukuya kumhlophe ngumgubo ocolekileyo onevumba elibonakalayo kunye nencasa

Isimo se-GMO:GMO Mahala

Ukupakisha: kwi-25kgs fiber drums

Ugcino: Gcina isikhongozeli singavulwanga kwindawo epholileyo neyomileyo, Zigcine kude nokukhanya okuqinileyo

Ubomi beShelf: iinyanga ezingama-24 ukusuka kumhla wokuvelisa

Imisebenzi:

-I-Osthole inokunyusa ukukhuselwa kwedlozi, ivuselele umnqweno wesini kwaye ibe nesenzo se-aphrodisiac

-I-Osthole iyakwazi ukomisa ukufuma kwaye ibulale iintshulube, ikhuphe ingqele ikhuphe umoya, ifudumale intso

qinisa yin.

-I-Osthole inomsebenzi wokunciphisa i-asthma kunye ne-antifungus, i-antivirus.

Impembelelo ye-Antiarrhythmic

Isicatshulwa samanzi kunye ne-coumadin epheleleyo evela kwi-fructus cnidium ineempembelelo ezicacileyo zokuthintela kwi-chloroform eyenza i-fibrillation ye-ventricular kwiigundane kunye ne-calcium chloride eyenza i-ventricular fibrillation kwiigundane.I-Fructus cnidium kunye ne-zanthoxylum acetaminophen nazo zinempembelelo ye-pharmacological kwaye inokuphucula i-ventricular electrofibrillation threshold kwimivundla.Ukukhutshwa kwamanzi, i-coumarin iyonke, i-cnidium, kunye ne-phenols ye-zanthoxylum yayinemiphumo ebalulekileyo yokuthintela ukuhamba kwee-ion ze-sodium kwi-membrane yeseli ye-myocardial.

I-Antihypertensive, inhibition of vascular dilatation

I-Osthol yayinesiphumo esibi se-inotropic esixhomekeke kwidosi kwi-atrium yasekhohlo yeehagu ze-guinea ezikwanti kunye nefuthe elibi lokuphindaphinda kwi-atrium yasekhohlo yeehagu ezizimeleyo.Ukongeza kwi-polarization eyenziwa yi-norepinephrine, i-CaCl2 kunye ne-K + ephezulu, i-aorta contraction dose-response curve yomvundla yatshintshelwa ngasekunene kwaye impendulo ephezulu yancipha, ebonisa indima ye-biosynthetic compound ekuphumleni i-vascular smooth muscle.I-Fructus cnidium inefuthe elithile le-antihypertensive.

Iziphumo kwinkqubo yokuphefumla

I-Cnidium monnieri iyonke i-coumarin kunye nokuphumla ngamachiza (i-histamine kunye ne-acetylcholine) ebangelwa yi-bronchial spasms kunye nendima ye-diastole bronchus ngokuthe ngqo, lo msebenzi unokuba yi-B-adrenaline receptor blockers block by propranolol, iigundane emva kokuba i-coumarin iyonke cnidium monnieri, ngokucacileyo ukwandisa inani le-phenol ebomvu. ukukhupha emzimbeni, kubonisa isenzo esinamandla se-expectorants.

Iziphumo ezichasayo

I-Cnidium cnidium kunye ne-phenolic zanthoxylum inokuthintela ukudumba kwegobolondo lendlebe yeempuku ezibangelwa yi-xylene kunye nokunyuka kwe-capillary permeability kwi-capillary cavity ebangelwa yi-acetic acid.I-Osthol kunye ne-acetonol yayinemiphumo ebalulekileyo yokuthintela ukuvuvukala kweenyawo kwiigundane kunye neempuku ezine-bilateral adrenal resection.I-Osthol nayo inokunciphisa umxholo we-PGE kwii-tissue ezivuthayo zonyawo oluvuvukalayo kwiigundane, kodwa i-osthol ayizange ithintele umxholo we-PGE kwiiscuphe ezivuthayo zonyawo oluvuthayo kwiigundane.

Iimpembelelo kwinkqubo ye-nervous

I-coumarin iyonke ye-cnidium cnidium inempembelelo yokuthintela kwinkqubo ye-nervous central.I-Osthol inokuphucula kakhulu impembelelo ye-hypnotic ye-pentobarbital sodium kwi-subthreshold hypnotic dose kwiimpuku, kwaye le mpembelelo ye-hypnotic inxulumene nedosi.I-Cnidium cnidium inokukhuthaza ukufunda kunye nenkumbulo yeempuku, kwaye iphucule kakhulu ukufunyanwa kwememori, ukudibanisa kunye nesiphumo se-Antiarrhythmic.

Isicatshulwa samanzi kunye ne-coumadin epheleleyo evela kwi-fructus cnidium ineempembelelo ezicacileyo zokuthintela kwi-chloroform eyenza i-fibrillation ye-ventricular kwiigundane kunye ne-calcium chloride eyenza i-ventricular fibrillation kwiigundane.I-Fructus cnidium kunye ne-zanthoxylum acetaminophen nazo zinempembelelo ye-pharmacological kwaye inokuphucula i-ventricular electrofibrillation threshold kwimivundla.Ukukhutshwa kwamanzi, i-coumarin iyonke, i-cnidium, kunye ne-phenols ye-zanthoxylum yayinemiphumo ebalulekileyo yokuthintela ukuhamba kwee-ion ze-sodium kwi-membrane yeseli ye-myocardial.

I-Antihypertensive, inhibition of vascular dilatation

I-Osthol yayinesiphumo esibi se-inotropic esixhomekeke kwidosi kwi-atrium yasekhohlo yeehagu ze-guinea ezikwanti kunye nefuthe elibi lokuphindaphinda kwi-atrium yasekhohlo yeehagu ezizimeleyo.Ukongeza kwi-polarization eyenziwa yi-norepinephrine, i-CaCl2 kunye ne-K + ephezulu, i-aorta contraction dose-response curve yomvundla yatshintshelwa ngasekunene kwaye impendulo ephezulu yancipha, ebonisa indima ye-biosynthetic compound ekuphumleni i-vascular smooth muscle.I-Fructus cnidium inefuthe elithile le-antihypertensive.

Iziphumo kwinkqubo yokuphefumla

I-Cnidium monnieri iyonke i-coumarin kunye nokuphumla ngamachiza (i-histamine kunye ne-acetylcholine) ebangelwa yi-bronchial spasms kunye nendima ye-diastole bronchus ngokuthe ngqo, lo msebenzi unokuba yi-B-adrenaline receptor blockers block by propranolol, iigundane emva kokuba i-coumarin iyonke cnidium monnieri, ngokucacileyo ukwandisa inani le-phenol ebomvu. ukukhupha emzimbeni, kubonisa isenzo esinamandla se-expectorants.

Iziphumo ezichasayo

I-Cnidium cnidium kunye ne-phenolic zanthoxylum inokuthintela ukudumba kwegobolondo lendlebe yeempuku ezibangelwa yi-xylene kunye nokunyuka kwe-capillary permeability kwi-capillary cavity ebangelwa yi-acetic acid.I-Osthol kunye ne-acetonol yayinemiphumo ebalulekileyo yokuthintela ukuvuvukala kweenyawo kwiigundane kunye neempuku ezine-bilateral adrenal resection.I-Osthol nayo inokunciphisa umxholo we-PGE kwii-tissue ezivuthayo zonyawo oluvuvukalayo kwiigundane, kodwa i-osthol ayizange ithintele umxholo we-PGE kwiiscuphe ezivuthayo zonyawo oluvuthayo kwiigundane.

Iimpembelelo kwinkqubo ye-nervous

I-coumarin iyonke ye-cnidium cnidium inempembelelo yokuthintela kwinkqubo ye-nervous central.I-Osthol inokuphucula kakhulu impembelelo ye-hypnotic ye-pentobarbital sodium kwi-subthreshold hypnotic dose kwiimpuku, kwaye le mpembelelo ye-hypnotic inxulumene nedosi.I-Cnidium cnidium inokukhuthaza ukufunda kunye nenkumbulo yeempuku, kwaye iphucule kakhulu ukufunyanwa kwememori, ukuhlanganiswa kunye nokucalulwa kwesikhokelo seempuku.

I-Anti-mutagenesis, i-anti-cancer effect

I-Cnidium, i-parsley b, i-bergamot lactone, i-isorhein, i-zanthoxylum acetaminophen kunye ne-toxin ye-zanthoxylum inomsebenzi ophezulu wokuthintela i-mutagenesis ye-aflatoxin B1.Isicatshulwa samanzi se-cnidium sinokunqanda i-S130 sarcoma, ukwandisa iintsuku zokuphila kunye nokuthintela ukukhula kwethumba.

I-Anti-mutagenesis, i-anti-cancer effect

I-Cnidium, i-parsley b, i-bergamot lactone, i-isorhein, i-zanthoxylum acetaminophen kunye ne-toxin ye-zanthoxylum inomsebenzi ophezulu wokuthintela i-mutagenesis ye-aflatoxin B1.Isicatshulwa samanzi se-cnidium sinokunqanda i-S130 sarcoma, ukwandisa iintsuku zokuphila kunye nokuthintela ukukhula kwethumba.

Usetyenziso:

I-Osthole isetyenziswa kakhulu kwimimandla yeemveliso ze-heath.I-Osthole ingasetyenziselwa njengemveliso ye-tonic kumadoda anamandla, izithako ezisebenzayo zamayeza kwizifo ze-gynecological.

I-Osthole isetyenziswa kakhulu kwimimandla yeemveliso zamayeza.I-Osthole ikwasetyenziswa njengemveliso yetonic kwisifo solusu esibukhali.

Ababoneleli ngemathiriyeli ekrwada abaliqela njengesiqinisekiso sobonelelo.AMaziko eNtsebenziswano awomeleleyo ukuxhasaIziko lebhotani/Iziko leMicrobiology/Iziko leSayensi neTekhnoloji/Dyunivesithi