Inositol

I-Inositol (i-hexahydroxycyclohexane) yindawo yendalo esasazwe ngokubanzi kwizicubu zezityalo nezilwanyana.Izicubu zezilwanyana ezityebileyo kuyoinositolingqondo, intliziyo, isisu, izintso, udakada, kunye nesibindi, apho kwenzeka simahla okanye njengenxalenye phospholipids.Phakathi kwezityalo, i-cereals yimithombo ecebileyo ye-inositol, ngokukodwa ngendlela ye-polyphosphoric acid esters, ebizwa ngokuba yi-phytic acids.Nangona kukho ii-isomers ezininzi ezinokusebenza kunye nezingasebenziyo, ukuqwalaselwa kwe-inositol njengesongezo sokutya kubhekiselwa ngokukodwa kwi-cis-1,2,3,5-trans-4,6-cyclohexanehexol engasebenziyo, ekukhetheke ukuba ibe yimyo-inositol.I-inositol ecocekileyo yinto ezinzileyo, emhlophe, emnandi, e-crystalline.I-Codex yeMichiza yoKutya ichaza ukuba ayivavanyi ngaphantsi kwe-97.0 yeepesenti, inyibilika phakathi kwe-224 kunye ne-227 °, kwaye iqulethe i-arsenic engaphezu kwe-3 ppm, i-10 ppm lead, i-20 ppm yesinyithi enzima (njenge-Pb), i-60 ppm sulfate, kunye ne-50 ppm. ikloridi.I-Inositol yacatshangelwa ixesha lokuba yivithamini kuba izilwanyana zokulinga kwi-synthetic diet zavelisa iimpawu zekliniki eziye zalungiswa nge-inositol supplementation.Nangona kunjalo, akukho cofactor okanye umsebenzi we-catalytic we-inositol ufunyenwe;inokuthi yenziwe kwaye yenzeke ekugxininiseni okuphezulu kwizicubu zezilwanyana.Ezi zinto ziphikisana nokuhlelwa kwayo njengevithamini.Imfuno yokutya emntwini ayizange isungulwe.

Igama leMveliso:Inositol

Inkcazo: Min 97.0%

Iimpawu zeMichiza:Ikristale emhlophe okanye umgubo oyikristale, awunavumba, kwaye uswiti;Uxinzelelo olunxulumeneyo: 1.752 (anhydrous), 1.524(dihydrate), mp 225~227 ℃ (anhydrous), 218 °C (dihydrate), indawo yokubilisa 319 °C.Inyibilike emanzini (25 °C, 14g / 100mL; 60 °C, 28g / 100mL), i-soluble kancinane kwi-ethanol, i-acetic acid, i-ethylene glycol kunye ne-glycerol, i-insoluble kwi-ether, i-acetone kunye ne-chloroform.Izinzile emoyeni;Izinzile kubushushu, i-asidi kunye ne-alkali, kodwa i-hygroscopic.

Inombolo yeCAS: 87-89-8

Uhlalutyo lokuqulathiweyo: Ubunzima obuchanekileyo besampulu ye-200 mg (eyomisiweyo ngaphambili kwi-105 ° C ye-4h), kwaye uyibeke kwi-beaker ye-250ml.Yongeza i-5ml yomxube phakathi kwesisombululo esinye se-sulfuric acid (TS-241) kunye ne-50 ye-acetic anhydride, uze uvale iglasi yokubukela.Emva kokufudumeza kwindawo yokuhlambela i-steam ye-20min, yipholise kwindawo yokuhlamba i-ice, yongeza amanzi ayi-100ml, ubilise i-20min.Emva kokupholisa, dlulisela isampuli kwi-funnel ye-250 mL yokwahlula usebenzisa inani elincinci lamanzi.Sebenzisa ngempumelelo i-30, 25, 20, 15, 10 kunye ne-5 mL yeklorofomu ukukhupha isisombululo amaxesha amathandathu (qala ngokugungxula ibhekile).Yonke isicatshulwa sekloroform yaqokelelwa kwifuneli yesibini eyahlulayo eyi-250m1.Hlamba isicatshulwa esixutywe nge-10ml yamanzi.Beka isisombululo sekhloroform ngefunnel ye-cotton wool kwaye uyidlulisele kwiflask ye-Soxhlet eyi-150ml yangaphambili.Sebenzisa i-10ml ye-chloroform ukuhlamba i-funnel eyahlulayo kunye ne-funnel, kwaye ifakwe kwisicatshulwa.Yijike ibe ngumphunga kwibhafu yomphunga, uze uyigqithisele kwi-oven eyi-105 °C ukuze yomiswe nge-1h.Yipholise kwidesikayitha, kwaye uyilinganise.Sebenzisa inani elifunyenweyo le-acetate ye-inositol ezintandathu ngokuphindaphinda nge-0.4167, oko kukuthi inani elihambelana ne-inositol (C6H12O6).

Umsebenzi:

1. Njengezongezo zokutya, zinefuthe elifanayo kwi-vitamin B1.Ingasetyenziselwa ukutya kwentsana kwaye isetyenziswe kwisixa se-210 ~ 250mg / kg;Isetyenziselwa ukusela kwisixa se-25 ~ 30mg / kg.
2. I-Inositol yivithamini eyimfuneko kwi-lipid metabolism emzimbeni.Inokukhuthaza ukufunxwa kwamayeza e-hypolipidemic kunye neevithamini.Ngaphezu koko, inokukhuthaza ukukhula kweeseli kunye ne-fat metabolism esibindini nakwezinye izicubu.Ingasetyenziselwa unyango lwe-adjuvant yesibindi esinamafutha, i-cholesterol ephezulu.Isetyenziswa kakhulu kwizongezo zokutya kunye nezongezo zokutya, kwaye isoloko yongezwa kwiintlanzi, i-shrimp kunye nokutya kwemfuyo.Isixa si-350-500mg / kg.
3. Imveliso yolunye uhlobo lwe-vitamin B eyinkimbinkimbi, enokukhuthaza i-cell metabolism, iphucule iimeko zezondlo zeseli, kwaye ingaba negalelo ekuphuhliseni, ukwandisa ukutya, ukuchacha.Ngaphezu koko, inokuthintela ukuqokelelwa kwamafutha esibindini, kwaye ikhawulezise inkqubo yokususa amanqatha amaninzi entliziyweni.Inesenzo esifanayo se-lipid-chemotactic njenge-choline, kwaye ngoko ke iluncedo kunyango lwe-hepatic fatty overives disease kunye ne-cirrhosis yesifo sesibindi.Ngokutsho "kwezondlo zokutya zokusetyenziswa kwemigangatho yezempilo (1993)" (Ikhutshwe nguMphathiswa wezeMpilo waseChina), ingasetyenziselwa ukutya kweentsana kunye neziselo eziqinisiweyo kwisixa se-380-790mg / kg.Ngamayeza odidi lwevithamini kunye neyeza lokwehlisa i-lipid elikhuthaza ukutyeba kwesibindi kunye nezinye izihlunu, kwaye ibe luncedo kunyango lwe-adjuvant yesibindi esinamafutha kunye ne-cholesterol ephezulu.Isetyenziswa ngokubanzi kwizongezo zokutya kunye nesiselo.
4. I-Inositol isetyenziswa ngokubanzi kwi-pharmaceutical, ikhemikhali, ukutya, njl. Inefuthe elihle ekuphatheni izifo ezifana ne-cirrhosis yesibindi.Isenokusetyenziswa kwizinto eziphambili zokuthambisa zokuthambisa, ezinexabiso eliphezulu lezoqoqosho.
5. Inokusetyenziswa njenge-reagent ye-biochemical kunye ne-pharmaceutical and organic synthesis;Inokunciphisa izinga le-cholesterol kwaye ibe nefuthe le-sedative.