I-LL-DOPA luhlobo lwendalo lweDOPA olusetyenziswa kunyango lwesifo sikaParkinson.I-L-DOPA yi-precursor ye-dopamine kunye nemveliso ye-tyrosine hydroxylase.Ithagethi: I-Dopamine Receptor L-DOPA (L-3,4-dihydroxyphenylalanine) yikhemikhali eyenziwe kwaye isetyenziswe njengenxalenye yebhayoloji eqhelekileyo yabantu, ezinye izilwanyana kunye nezityalo.Ezinye izilwanyana kunye nabantu bayenza nge-biosynthesis ukusuka kwi-amino acid L-tyrosine.I-L-DOPA ngumanduleli we-neurotransmitters i-dopamine, i-norepinephrine (i-noradrenaline), kunye ne-epinephrine ngokudibeneyo eyaziwa ngokuba yi-catecholamines.I-L-DOPA inokuveliswa kwaye ikwimo ecocekileyo ithengiswa njengechiza le-apsychoactive kunye ne-INN levodopa;Amagama okurhweba aquka iSinemet, iParcopa, i-Atamet, i-Stalevo, i-Madopar, i-Prolopa, njl. Njengechiza lisetyenziselwa unyango lweklinikhi yesifo sika-Parkinson kunye ne-dopamine-responsive dystonia.I-L-DOPA iwela umqobo okhuselayo wegazi-ingqondo, ngelixa i-dopamine ngokwayo ayinako.Ke, i-L-DOPA isetyenziselwa ukunyusa ugxininiso lwe-dopamine kunyango lwesifo sika-Parkinson kunye ne-dopamine-responsive dystonia.Olu nyango lwenziwa ukuba lube luncedo kwaye lwangqinwa ngokonyango nguGeorge Cotzias kunye noogxa bakhe, apho baphumelela ibhaso le-Lasker lika-1969.Ukongeza, i-L-DOPA, elawulwa ngokubambisana kunye ne-DDCI ye-peripheral, iphandwe njengonyango olunokubakho kwi-syndrome yomlenze ongenakuphumla.Nangona kunjalo, izifundo zibonise "akukho mfanekiso ucacileyo weempawu ezincitshisiweyo".I-L-DOPA ngumanduleli we-neurotransmitters i-dopamine, i-norepinephrine (i-noradrenaline), kunye ne-epinephrine (i-adrenaline) eyaziwa ngokuba yi-catecholamines.
Ngaphandle kwendima yayo yendalo kunye nebalulekileyo yebhayoloji, i-L-DOPA ikwasetyenziswa kunyango lwezonyango lwesifo sikaParkinson kunye ne-dopamine-responsive dystonia.Xa isetyenziswa kwimeko yoxubo-mayeza, igama le-INN elithi 'levodopa' lidla ngokusetyenziswa.
I-Levodopa yindalo eyongezelelweyo yokutya kunye neziyobisi zengqondo ezifumaneka kwiintlobo ezithile zokutya kunye nemifuno (umzekelo, i-Mucuna pruriens, okanye i-velvet bean), kwaye yenziwe nge-amino acid L-tyrosine kumzimba we-mammalian kunye nengqondo.
I-Levodopa ngumanduleli we-neurotransmitters i-dopamine, i-norepinephrine (i-noradrenaline), kunye ne-epinephrine (i-adrenaline) eyaziwa ngokuba yi-catecholamines.
Ngaphandle kwendima yayo yendalo kunye nebalulekileyo yebhayoloji, i-L-DOPA ikwasetyenziswa kunyango lwezonyango lwesifo sikaParkinson kunye ne-dopamine-responsive dystonia.Xa isetyenziswa kwimeko yoxubo-mayeza, igama le-INN elithi 'levodopa' lidla ngokusetyenziswa.
Igama lemveliso: L-dopa 98%
Umthombo wezityalo:Mucuna Pruriens Extract
Inxalenye: Imbewu (Yomisiweyo, 100% Yendalo)
Isithako esisebenzayo: Levodopa (L-dopa)
Indlela Yokukhupha: Amanzi/ Utywala obuziinkozo
Ifom: umgubo omhlophe-omhlophe
Inkcazo: 5% -99%
Indlela yoVavanyo : HPLC
Inombolo yeCAS: 59-92-7
Imolekyuli esesikweni: C9H11NO4
Ubunzima bemolekyuli: 197.19
Ukunyibilika: Ukunyibilika okulungileyo kwisisombululo se-hydro-alcoholic
Isimo se-GMO:GMO Mahala
Ukupakisha: kwi-25kgs fiber drums
Ugcino: Gcina isikhongozeli singavulwanga kwindawo epholileyo neyomileyo, Zigcine kude nokukhanya okuqinileyo
Ubomi beShelf: iinyanga ezingama-24 ukusuka kumhla wokuvelisa
Umsebenzi:
- 1 .Ii-anti-paralysis agitans.Ngokusebenzisa umqobo wegazi-ubuchopho kwithishu yengqondo, kodwa nge-decarboxylation ye-dopa decarboxylase kwi-dopamine, dlala indima.
2. Ukungcangcazela okubalulekileyo kunye nokukhubazeka ukukhubazeka kwe-agitans syndrome ye-non-drug immunogenicity, kunye nokukhanya okungcono, okunamandla, okanye amahlwempu asebekhulile.
3. Ukukhuthaza ukukhula kwezihlunu, ukuncipha komzimba.
4. Ukunyuka kwamathambo kunye nokuguqulwa kwe-osteoporosis.
5 .Izongezo zokutya.
6. Nyanga i-parkinsonism kunye ne-Pakinsonism syndrome, i-hepatic coma, imisebenzi ye-hub ukuphucula isigulana sivukile, ukuphuculwa kweempawu.
7 .Khuthaza ubuthongo, uphucule amajoni omzimba.
8 .Ukunciphisa umzimba.
9 Ukwandisa ukuxinana kwamathambo kunye nokuguqulwa kwe-osteoporosis, ukwandisa amandla emisipha, ukuphucula i-libido kunye nokusebenza ngokwesondo.
Isicelo:
I-1.Mucuna Pruriens Extract ingasetyenziswa njengezongezo zokutya.
I-2.I-Mucuna Pruriens Extract isetyenziswe njengenxalenye kwi-adhesives yaselwandle esetyenziswa yi-pelagic life.
I-3.I-Mucuna Pruriens Extract inokukhuthaza ukukhula kwemisipha kunye nokunyuka kwamathambo kunye nokuguqulwa kwe-osteoporosis.
I-4.I-Mucuna Pruriens Extract yandisa ubuninzi bamathambo kunye nokuguqulwa kwe-osteoporosis, ukwandisa amandla emisipha, ukuphucula i-libido kunye nokusebenza ngokwesondo.
I-5.Ukusetyenziswa kweklinikhi, i-Mucuna Pruriens Extract ilawulwa kulawulo lwe-Parkinson's disease kunye ne-dopa-responsive dystonia.
6.Ngokokungcangcazela okubalulekileyo kunye nokukhubazeka kokukhubazeka i-agitans syndrome ye-non-drug immunogenicity, kunye nokukhanya okungcono, okunamandla, okanye abantu abadala abahluphekayo.
7.Nyanga i-parkinsonism kunye ne-Pakinsonism syndrome, i-hepatic coma, imisebenzi ye-hub ukuphucula isigulana sivukile, ukuphuculwa kweempawu.
I-8.I-Mucuna Pruriens Extract i-anti-paralysis agitans.Ngokusebenzisa umqobo wegazi-wengqondo kwithishu yengqondo, kodwa nge-decarboxylation ye-l-dopa decarboxylase kwi-dopamine, dlala indima.
I-9.I-Mucuna Pruriens Extract isetyenziselwa ukuthuthumela okubalulekileyo kunye nokukhubazeka kokukhubazeka kwe-agitans syndrome ye-non-drug immunogenicity, kunye nokukhanya okungcono, okunzima, okanye abantu abadala abahluphekayo.
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