Igama lomkhiqizo:Pyrlolloquinoline quonone solione usawoti
Inombolo ye-CAS: 122628-50-6 / 72909-34
Isisindo Molecular: 374.17 / 330.21
Ifomula ye-molecular: c14h4n2na2 / c14h6N2O8
Ukucaciswa: I-PQQ Dirodium usawoti 99%; pqq acid 99%
Ukubukeka: I-Orange ebomvu kuya kobomvu i-powder enhle onsundu.
Isicelo: Kusetshenziswa kabanzi ngesengezo sokudla kanye nokudla okunempilo.
Isitoreji: Kugcinwe esimweni sokuphumula nosomile, suka kude neLanga eliqondile.
I-Pyrlolquinoline Quinone Doolone SALT (PQQ)
Ukubuka konke komkhiqizo
I-Pyrlolquinoline Quoonone SALT (CAS No: 122628-50-6), ivame ukufushaniswa njenge-PYRORORE Ngokwemvelo etholakala emhlabathini, eKiwifruit, ukudla okubilisiwe, nobisi lwebele lomuntu, i-PQQ idlala indima ebalulekile ekukhiqizeni amandla amaselula kanye nomsebenzi we-mitochondrial. Ngaphezulu kwama-80% wezithasiselo zokudla zisebenzisa lefomu kasawoti le-sodium ngenxa yokuqina kwalo okuthuthukisiwe kanye nokuzinikela.
Izinzuzo ezibalulekile
- Ithuthukisa amandla amaselula: isekela i-bitochondrial biogenesis, ethuthukisa i-metabolism yamandla kanye nokunciphisa ukukhathala.
- Ukuxhaswa kwengqondo: Kuvikela ama-neurons kumonakalo oxetutive, kuthuthukisa inkumbulo, futhi kunciphise ukwehla okuhlobene nobudala.
- I-Cardiovascular Health: Yehlisa ukucindezela okuthi oxidative futhi isekela umsebenzi wenhliziyo ngokusebenzisa izindlela ze-antioxidant.
- I-Antioxidant Defense: I-Neutrikes Free Radicals kanye nama-antioxidants antioxidants njenge-glutathione, ekhuthaza impilo yeselula yonke.
Ukuxhaswa Kwesayensi
- Isimo se-FDA GRAS: samukelwa njengoba ngokuvamile samukelwa njengephephile (GRAS) yi-US FDA ukuze isetshenziswe ekudleni nasezithambekeni.
- Ukuvunywa kwe-EFSA: Kuhlolwe ukuphepha ngaphansi komthetho wokudla wenoveli we-EU (EU 2015/2283), ngezimo ezithile zokusebenzisa.
- Ucwaningo lweMitholampilo: Khombisa ukusebenza ngempumelelo ekuthuthukiseni umsebenzi wobuchopho, ukunciphisa ukucindezelwa kwe-oxidative, kanye nokwenza ngcono ukusebenza kahle kwe-mitochondrial ezilingweni zabantu.
Ukucaciswa kobuchwepheshe
Impahla | Bonisana |
---|---|
Ifomula yamangqamuzana | C₁₄Hh₄n₂na₂o₈ |
Isisindo molecular | 374.17 g / mol |
Ukubonakala | I-Reddish-brown powder |
Ubumsulwa | ≥98% (HPLC) |
Ubuhlakaniselo | Insolule yamanzi (3 g / l ngo-25 ° C) |
Ukubeka | Gcina endaweni eyomile, epholile (2-8 ° C Kunconyiwe); Gwema ukukhanya nomswakama. |
Ukusetshenziswa okunconyiwe
- Umthamo: 10-40 mg / usuku lwabantu abadala. Wabasaqalayo kufanele baqale nge-10-20 mg futhi balungiswe ngokususelwa ekuphenduleni.
- Izakhi: Ilungele ama-caplule, amaphilisi kanye nezinhlanganisela eziyimpuphu. Iyahambisana nokwakhiwa kwama-vegan ne-gluten.
Ukuqinisekisa ikhwalithi
- Izitifiketi: Kwenziwe ngaphansi kwamazinga we-HACCP kanye namazinga we-ISO, ukuqinisekisa ukuphepha nokulandela umkhondo.
- Okungenzi oku-GMO: Kukhiqizwe nge-Fermentation kusetshenziswa okungaguquki kofuzoI-HyphomicRobium Denitrificans.
Ukuhambisana nokulawula
- Imikhawulo yemakethe ye-EU: Ayigunyaziwe njengamanje ukuthengiswa e-EU, UK, Iceland, Liechtenstein, noma eSwitzerland ngaphandle kwemvume yangaphambilini.
- Izidingo zokulebula: Imikhiqizo kumele ifake:
- "Kwabantu abadala kuphela. Akunconyelwe abesifazane abakhulelwe noma abalekayo.".
- "I-Pyrlocroquinoline Quinone Dionodium Usawoti"njengegama eliqokiwe eliqokiwe.
Izinja
- Izithasiselo Zokudla: Amandla Energy Boosters, Abathuthukisi Abaqondayo, kanye nokwakheka okulwa nokuguga.
- Ukudla okusebenzayo: Iziphuzo ezivikelwe, imigoqo yezempilo kanye nemiphumela yokudla.
- Izimonyo: Kusetshenziswe njengokuvikelwa kwesikhumba kuma-anti-aguring okhilimu.
Kungani ukhethe i-PQQ yethu?
- Ukuhlanzeka okuphezulu: ≥98% as assay ngokulawulwa kwekhwalithi eqinile.
- Ukuthobela umhlaba wonke: Ukuholwa okuningiliziwe kwimithetho eqondene nemakethe.
- Ukusekelwa Kocwaningo: Kusekelwa izifundo ezibukezwe kontanga ezingaphezu kuka-20 ngokuphepha nangokusebenza ngempumelelo.
Xhumana nathi
Okwezintengo eziningi, izitifiketi zokuhlaziywa, noma usizo lokulawula, finyelela eqenjini lethu lokuthengisa. Sinikezela ngezixazululo ezenzelwe ukuhlangabezana nezidingo zakho zokwakheka.
Pyrlocroquinoline quinone imithombo yokudla
I-PQQ ngokwemvelo ikhona ekudleni okunemifino, izithelo, kanye nemifino (umkhondo), futhi amazinga aphezulu we-PQQ angatholwa emikhiqizweni ye-soybean ebilisiwe, efana ne-kiwifruit, iTapeseed, isinaphi, isipinashi, njll.
G.I-Hag ithole ukuthi kwakuyi-redox cofactor yesithathu kuma-bacteriya ngemuva kweNicotinamide ne-flavin (yize ecabanga ukuthi kwakungu-Naphthoquququone). U-Anthony noZatman bathole futhi ama-cofactors angaziwa kabusha e-ethanol dehydrogenase. Ngo-1979, usawoti kanye nozakwabo kanye nozakwabo kanye nozakwabo bakhiphe lesi sisekelo se-pseudo esivela ku-methanol dehydrogenase yama-dehydrogenates futhi akhombe isakhiwo salo se-molecular. U-Adachi nozakwabo bathola ukuthi i-acetobaccter nayo iqukethe i-PQQ.
Indlela yokwenza isenzo se-pyrlocroquinoline quinone
I-Pyrlolquinoline Quinone (PQQ) iyinhlangano encane ye-quone molecule, enomphumela we-redox, inganciphisa i-oxidant (antioxidant); Ngemuva kwalokho kutholakala kwifomu elisebenzayo yi-glutathione. Kubukeka sengathi zizinzile ngoba zingabhekana nezinkulungwane zemijikelezo ngaphambi kokudla, futhi okusha ngoba kuhlobene nesakhiwo samaseli (ama-antiotenoids afana nama-antaxanthin, lapho adlala khona ama-antioxidant arlectionary ngokulinganayo). Ngenxa yokusondela, i-PQQ ibonakala idlala indima eduze kwamaprotheni anjenge-carotenoids kuma-membranes weseli.
Le misebenzi ye-redox ingaguqula imisebenzi yama-protein kanye nezindlela zokudlulisela iziginali. Yize kunezifundo eziningi ezithembisayo eVitro (ngaphandle kwamamodeli aphilayo), eminye imiphumela ethembisayo ye-PQQ supplement ihlobene kakhulu nokushintsha izindlela ezithile zokudlulisela izimpawu noma izinzuzo zazo ku-mitochondria noma izinzuzo zazo ku-mitochondria. (Khiqiza okunye futhi kuthuthukise ukusebenza).
Kuyi-coenzyme ku-bacterium (ngenxa yamagciwane, kufana namavithamini we-B-), kodwa kubonakala sengathi akubonakali kudluliselwe kubantu. Njengoba lokhu kungasebenzi kubantu, i-athikili ka-2003 ngokwemvelo, iphephabhuku lesayensi, lithi umbono wokuthi i-PQ iyingxenye yevithamini iphelelwe yisikhathi esinjengokuthi "kubhekwa njengento enjengevithamini."
Mhlawumbe okuphawuleka kakhulu kungumphumela we-PQQ ku-Mitochondria, enikeza amandla (ATP) kanye nokulawula imetabolism yeseli. Abaphenyi babone kakhulu umthelela we-PPQ ku-mitochondria futhi bathola ukuthi i-PQQ ingakhuphula inani le-mitochondria futhi lithuthukise ukusebenza kahle kwe-mitochondria. Lesi yisizathu esibalulekile esenza i-PPQ ilusizo kangaka. Ama-enzyme aqukethe i-PQQ ayaziwa ngokuthi yi-glucose dehydrogenase, i-quinoa protein esetshenziswa njengenzwa ye-glucose.
Izinzuzo ze-pyrloquinoline quinone
Ukuba ne-mitochondria yabo okungcono kakhulu kubaluleke kakhulu empilweni enempilo ongathola izinzuzo eziningi ngenkathi uthatha i-PPQ. Nazi ezinye zezinzuzo ze-Pyrlolquinoline Quinone
Ukwanda kwama-Cell Energy
Ngoba iMitochondria ikhiqiza amandla amaseli, futhi i-PQQ isiza i-mitochondria isebenze ngempumelelo, amandla kumaseli akhuphuka awonke; Le yi-pyrloquinoline quonone mitochondlial meshini. Amandla weselula angasetshenziswanga aphambukiswa kwezinye izingxenye zomzimba. Uma umzimba wakho ungenawo amandla usuku lonke, noma uzizwa ukhathele noma umile, khona-ke amandla andayo e-PPQ ibalulekile kuwe. Olunye ucwaningo luthole ukuthi ngemuva kokuthatha i-PQQ, izifundo ezinkingeni zamandla okubikwa zazingaphansi kakhulu ukukhathala. Uma ufuna okuthile ukwandisa amandla akho, i-PQQ ingakusiza ngalokho.
Ukuvimbela ukwehla kwengqondo
Ngokuthuthukiswa kwesayensi, ososayensi bathole ukuthi i-Nerve Friedge factor (ngf) ingakhula futhi ilulame. Ngasikhathi sinye, i-PQQ ikhonjiswe ukuthi ibe nomthelela omuhle ku-NGF futhi yandisa ukukhula kwezinzwa ngamahlandla angama-40. I-NGF ibalulekile ekwakhekeni nasekugcinweni kwama-neurons amasha, futhi ingabuyisela ama-neurons alimele angavimba umsebenzi wokuqonda. Ama-neurons angamaseli adlulisela imininingwane, ngakho-ke ubuchopho bethu bungaxhumana phakathi kwabo nezinye izingxenye zomzimba. Ukuthuthukisa ikhwalithi nenani lama-neurons kungathuthukisa ukuqonda. Ngakho-ke, i-PQQ inentuthuko yesikhashana.
Ukusekela Impilo Yezinhliziyo
I-Pyrlolquinoline Quinine ihlinzeka ngokuxhaswa kwe-antioxidant kanye ne-mitochondrial. Ucwaningo luye lwabonisa ukuthi i-PQQ neCoq10 yokusekela umsebenzi we-MyOcardial kanye nokusetshenziswa okulungile komoya-mpilo. I-Pyrlocroquicoinline Quinone ivimbela ukucindezela okuthi oxidative ngokuvuselelwa kwayo.
Okunye ukusebenza ngempumelelo:
Ngaphandle kwalezi zinzuzo ezintathu eziphambili ezibhalwe ngenhla, i-PQQ inikeza ezinye izinzuzo ezingaziwa kahle. I-PQQ ingadlala indima ekuvuseleleni ukuvuvukala komzimba, kungcono ukulala kwakho futhi kungathuthukisa ukuzala, kepha kudingeka ucwaningo oluningi ukuze uzuze iziphetho eziqondile. Njengoba ucwaningo luqhubeka, izinzuzo eziningi zokuthatha i-PQQ zingatholakala.
Umthamo we-pyrloquinoline quinone
Njengamanje, akekho uhulumeni noma ngubani ochaze umthamo we-pyrlocroquinoline. Kodwa-ke, abanye abantu nezikhungo bayenzile izivivinyo eziningi zebhayoloji kanye nokuhlolwa komuntu emthanjeni ofanele we-pyrlocroquinoline quoder powder. Ngokubona nokuqhathanisa ukusebenza kwezihloko, kuphetha ngokuthi umthamo ofanele we-PQQ uneminyaka engama-20 mg-50 mg. Njalo dlulisa udokotela wakho uma kukhona imibuzo elisandisiwe. Njenge-biopqq pyrlocroquinoline kaQuoneone disedium usawoti.
Imiphumela emibi ye-PQQ
Kusukela ngo-2009, izithasiselo zokudla eziqukethe i-Pqq NA 2 ziye zathengiswa e-United States ngemuva kwesaziso esisemthethweni nge-Food and Drug Administration (FDA), futhi akukho mbono onzima obikiwe. Uma ufuna ukwengeza ama-pyrloququinoline quelone izithasiselo ekudleni kwakho, kubalulekile ukukhumbula into eyodwa. Njengoba ingadingi i-PQQ eningi kakhulu ukukhiqiza umphumela, imithamo eminingi igcinwa ebangeni elincane. Ngakho-ke, iningi labantu akudingeki likhathazeke nganoma yimiphi imiphumela emibi ye-Pyrrolquinoline. (Lokho uthenge i-pyrloquenoline quinone PQQ sunger evela emakethe)