I-Paclitaxel 99.0%

I-Paclitaxel iyinhlanganisela ye-monomer diterpenoid ekhishwe ku-Natural Plant Paclitaxel bark, iwuhlobo lwe-metabolites yesibili eyinkimbinkimbi, okwamanje iqondwa kuphela umuthi ongakhuthaza i-microtubule polymerization kanye nokuzinza kwama-microtubules ahlanganisiwe.Ukulandelela isotopu kubonise lokhopaclitaxelyayiboshelwe kuphela kuma-microtubules enziwe nge-polymerized, hhayi ku-polymerized tubulin amabili.Oxhumana naye weselulapaclitaxelngemuva kokuqoqwa kwenani elikhulu lama-microtubules kumaseli, aphazamisa ukuqoqwa kwe-microtubule yemisebenzi ehlukahlukene yamangqamuzana, ikakhulukazi ukuhlukaniswa kwamaseli ku-mitosis, kuvimbe ukuhlukaniswa kwamaseli okuvamile.

Igama lomkhiqizo:Paclitaxel99.0%

Ifomu: I-crystalline powder emhlophe
Ukucaciswa: 99%

Indlela Yokuhlola: I-HPLC

Inombolo ye-CAS: 33069-62-4

I-Molecular Formula:C47H51NO14

Iphuzu elibilayo:957.115 °C ku-760 mmHg
Isisindo se-molecule: 853.91
Isimo se-GMO:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

Umsebenzi:

I-1.I-Paclitaxel isetshenziswa kakhulu kumdlavuza wesibeletho nowebele, umdlavuza wamaphaphu, umdlavuza we-colorectal, melanoma, umdlavuza wekhanda nentamo, i-lymphoma, futhi iphinde ibe nomthelela othile kumathumba obuchopho.

I-2.Kuyizidakamizwa zokuzinza ezingakhuthaza i-microtubule polymerization kanye ne-microtubule polymerization.
I-3.Kuzoqoqwa inani elikhulu lama-microtubules emangqamuzaneni ngemva kokuchayeka ku-paclitaxel, ukuqoqwa kwama-microtubules kuphazamisa imisebenzi yamaseli, ikakhulukazi, ukuhlukaniswa kwamaseli amisiwe ku-mitosis, ukuvimbela ukuhlukaniswa kwamaseli okuvamile.

Isicelo:

Isetshenziswa ocwaningweni lwesakhiwo kanye nokusebenza kwama-microtubles abe yi-tubulin.I-Paclitaxel manje isisetshenziselwa ukwelapha iziguli ezinomdlavuza wamaphaphu, i-ovary, umdlavuza webele, umdlavuza wekhanda nentamo, kanye nezinhlobo ezithuthukisiwe ze-Kaposi's sarcoma.I-Paclitaxel iyi-mitotic inhibitor esetshenziswa ekwelapheni umdlavuza.