Khoom npe:Sib 7p

Lwm Lub Npe: Compound7P; 2-[(2-methoxyphenyl) [(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide ;2-(N-(2-methoxyphenyl)-4- methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide

CAS Nr:1890208-58-8

Cov ntsiab lus: 99.0%

Xim: dawb hmoov nrog cov yam ntxwv tsw thiab saj

GMO Status: GMO Dawb

Ntim: hauv 25kgs fiber ntau nruas

Cia: Khaws lub thawv tsis qhib hauv qhov chaw txias, qhuav, Khaws kom deb ntawm lub teeb muaj zog

Lub neej txee: 24 lub hlis txij li hnub tsim khoom

Compound 7p tau pom tias ua rau muaj kev loj hlob ntawm GAP-43-zoo axons nyob rau hauv cov tsiaj qauv ntawm optic paj hlwb raug mob, tawm tswv yim hais tias cov neurite outgrowth kev ua si ntawm compound 7p nyob rau hauv vitro txhais mus rau stimulation ntawm axon regeneration nyob rau hauv Vivo.

Nyob rau hauv tus qauv tsiaj ntawm optic paj hlwb raug mob, compound 7p tau pom los txhawb kev loj hlob ntawm qhov sib txawv-43 zoo axons, qhia tias in vitro neurite outgrowth kev ua ntawm compound 7p txhais rau hauv stimulation ntawm axon regeneration nyob rau hauv vivo.further optimization ntawm compound 7p thiab elucidation ntawm cov mechanisms uas nws elicits axon regeneration nyob rau hauv vivo yuav muab lub hauv paus rational rau yav tom ntej kev siv zog los txhim kho cov tswv yim kho mob.

Compound 7P yog hais txog cov organic compound uas muaj xya carbon atoms. Hauv cov organic chemistry, carbon yog ib qho tseem ceeb vim nws tuaj yeem tsim kev ruaj khov nrog lwm cov atoms, suav nrog carbon atoms, tsim cov molecules complex. Cov molecules no tuaj yeem muaj ntau yam khoom thiab kev ua haujlwm, ua cov pa roj carbon monoxide ua lub tsev thaiv ntawm lub neej. Hauv cov qauv tsiaj ntawm optic paj hlwb raug mob, compound 7p tau pom los txhawb kev loj hlob ntawm GAP-43-positive axons, qhia tias kev loj hlob ntawm neurite ntawm compound 7p hauv vitro txhais ua stimulation ntawm axonal regeneration hauv vivo. Compound 7P hmoov yog cov hmoov dawb rau cov hmoov dawb uas tsim los ua ib qho kev sib xyaw ua ke rau kev txheeb xyuas ntawm dual-acting thromboxane receptor antagonist inhibitors. Qhov tseeb, compound 7p pom kev xaiv rau prostaglandin I2 synthase (PTGIS, CYP8A1) txheeb ze rau thromboxane synthase (CYP5A1). Nootropic compound 7P hmoov txhawb kev loj hlob ntawm Gap-43-zoo axons, yog li stimulating axonal regeneration hauv lub cev. High-quality Complex 7p yog tsim los txhim kho kev sib koom tes, txhim kho kev xav thiab pab tiv thaiv qaug zog. Nws kuj tiv thaiv lub hlwb oxidation thiab pab tua lub hlwb puas los ntawm kev haus cawv.

Muaj nuj nqi:

Axon regeneration tom qab raug mob nyob rau hauv lub hauv nruab nrab lub paj hlwb yog hampered nyob rau hauv ib feem vim hais tias yog ib tug muaj hnub nyoog-dependent poob nyob rau hauv lub intrinsic axon loj hlob muaj peev xwm, thiab ib tug ntawm cov tswv yim los txhawb axon kev loj hlob nyob rau hauv raug mob neurons muaj pharmacological manipulation ntawm implicated signaling pathways.no peb qhia. phenotypic cell-raws li tshuaj ntsuam ntawm cov tsev qiv ntawv tshuaj thiab cov qauv-kev ua haujlwm-kev coj ua kom zoo uas ua rau Kev txheeb xyuas ntawm cov compound 7p uas txhawb nqa kev loj hlob ntawm neurite ntawm kab lis kev cai thawj neurons tau los ntawm hippocampus, cerebral cortex, thiab retina. Nyob rau hauv ib tug tsiaj qauv ntawm optic paj hlwb raug mob, compound 7p tau qhia kom induce loj hlob ntawm qhov sib txawv-43 zoo axons, qhia hais tias nyob rau hauv vitro neurite outgrowth kev ua si ntawm compound 7p txhais mus rau hauv stimulation ntawm axon regeneration nyob rau hauv vivo.further optimization ntawm compound 7p thiab elucidation ntawm cov mechanisms uas nws elicits axon regeneration nyob rau hauv vivo yuav muab lub hauv paus rational rau yav tom ntej kev siv zog los txhim kho cov tswv yim kho mob.
Daim ntawv thov:

Nws yog tam sim no ib tug nootropic ntse tshuaj uas portrays nws tus kheej nyob rau hauv ib tug ntawm cov haib racetams nyob rau hauv lub nootropic ntug. Ua los ntawm ib chav kawm ntawm cov tebchaw hu ua racetams, thiab ua rau tsis yog acetylcholine nkaus xwb tab sis kuj GABA receptors nyob rau hauv lub hlwb, qhov no muaj peev xwm ntawm activating ob leeg cholinergic thiab glutamate receptors ntawm lub paj hlwb cortex, thiab yog ib tug revolutionary racetam tshuaj vim nws tsis tshua muaj heev. tshwj xeeb mechanism ntawm kev txiav txim. Fasoracetam tam sim no tseem qhia tau cov txiaj ntsig zoo li tshuaj tiv thaiv kev nyuaj siab, ADHD stimulant, thiab anxiolytic, nws kuj, raws li muaj pov thawj nyob rau hauv lub chaw soj nstuam thoob plaws lub teb chaws, pab nrog tsim thiab khaws cia tshiab nco.