wepụ peony ọcha

Aha ngwaahịa:Mwepụta Peony Whitentụ ntụ

Aha ọzọ:Ntụ ntụ na-acha ọcha nke China

Isi mmalite nke ahịhịa:Radix Paeoniae Alba

Efrata:Mkpokọta glucosides nke Paeonia (TGP):Paeoniflorin, Oxypaeoniflorin, Albiflorin, Benzoylpaeoniflorin

Nkọwapụta:Paeoniflorin10% ~ 40% (HPLC), 1.5%Albasides, 80%Glycosides

Nọmba CAS:23180-57-6

Agba: Yellowish-aja ajantụ ntụna njirimara isi na uto

GMOỌnọdụ: GMO efu

Mbukota: na 25kgs fiber drum

Nchekwa: Debe akpa na-emegheghị n'ebe dị jụụ, ebe kpọrọ nkụ, zere ọkụ siri ike

Ndụ shelf: ọnwa 24 site na ụbọchị mmepụta

Mwepụta Peony Whitena-ezo aka na mmịpụta nke ihe ndị na-arụ ọrụ sitere na peony ọcha site na nkà mmụta sayensị dịka teknụzụ pụrụ iche.Dịka nyocha nke ndị ọkà mmụta si kwuo, ihe ndị na-arụ ọrụ na-emepụta peony ọcha maka ahụ mmadụ bụ Chart.Anọ n'ime ihe kacha mkpa bụ Paeoniflorin, Oxypaeoniflorin, Albiflorin, na Benzoylpaeoniflorin.

A na-ewepụta ihe na-acha ọcha peony site na mgbọrọgwụ akpọnwụ nke Paeonia lactiflora Pall., osisi nke ezinụlọ Ranunculaceae.Isi ihe mejupụtara ya bụ paeoniflorin, nke enwere ike iji ya mee ihe ọ bụghị naanị na ngalaba ahụike kamakwa na ụlọ ọrụ ịchọ mma.Mwepụta peony ọcha bụ ihe mgbochi ọrụ PDE4 dị oke mma.Site n'igbochi ọrụ PDE4, ọ nwere ike ime ka cAMP nke dị iche iche na-egbuke egbuke na sel ndị na-adịghị ahụkebe (dị ka neutrophils, macrophages, T lymphocytes na eosinophils, wdg) rute ntinye uche zuru oke iji gbochie mmalite nke sel ndị na-egbuke egbuke ma na-enwe mmetụta mgbochi mkpali.Ọ nwekwara analgesic, antispasmodic, mgbochi ọnya, vasodilator, ụba akụkụ ọbara eruba, antibacterial, imeju-echebe, detoxifying, mgbochi mutagenic, na mgbochi tumor mmetụta.

1,2,3,6-tetragalloyl glucose, 1,2,3,4,6-pentagalloyl glucose na hexagalloyl glucose kwekọrọ na heptagalloyl glucose dịpụrụ adịpụ na tannin nke mgbọrọgwụ peony ọcha.O nwekwara catechin dextrorotatory na mmanụ na-agbanwe agbanwe.Mmanụ na-agbanwe agbanwe nke ukwuu nwere benzoic acid, peony phenol na mmanya ndị ọzọ na phenols.1. Paeoniflorin: usoro ihe omimi C23H28O11, arọ molecular 480.45.Hygroscopic amorphous ntụ ntụ, [α] D16-12.8 ° (C=4.6, methanol), tetraacetate bụ kristal agịga na-enweghị agba, mp.196℃.2. Paeonol: Okwu ọnụ bụ paeonol, peony mmanya, paeonal, na peonol.Usoro ihe omimi C9H10O3, arọ molekul 166.7.kristal na-enweghị agba agịga (ethanol), mp.50 ℃, ubé soluble na mmiri, nwere ike volatilize na mmiri vepo, soluble na ethanol, ether, acetone, chloroform, benzene na carbon disulfide.3. Ndị ọzọ: Nwere obere ego nke oxypaeoniflorin, albiforin, benzoylpaeoniflorin, lactiflorin, a ọhụrụ monoterpene paeoniflorigenone na neuromuscular igbochi mmetụta na ụmụ oke, 1,2,3,4,6-Pentagalloylglucose na antiviral mmetụta, gallotannin, gallotannin, d- acid, ethyl gallate, tannin, β-sitosterol, sugar, starch, imi, wdg.

Ọrụ:

1. Mgbochi mkpali, antibacterial na antiviral mmetụta.White peony wepụ nwere ịrịba inhibitory mmetụta na akwa ọcha nnukwu mkpali edema na oke ma na-egbochi mgbasa nke owu bọọlụ granuloma.Mkpokọta glycosides nke paeony nwere mgbochi mkpali na mmetụta immunomodulatory dabere na anụ ahụ na oke nwere ọrịa ogbu na nkwonkwo.Nkwadebe peony na-acha ọcha nwere ụfọdụ mmetụta mgbochi na Staphylococcus aureus, hemolytic Streptococcus, pneumococcus, Shigella dysenteriae, Typhoid bacillus, Vibrio cholerae, Escherichia coli na Pseudomonas aeruginosa.Na mgbakwunye, 1: 40 decoction peony nwere ike igbochi nje Jingke 68-1 na nje herpes.
2. Mmetụta hepatoprotective.Mwepụta nke peony na-acha ọcha nwere mmetụta mmegide dị ukwuu na mmebi imeju yana mmụba SGPT nke D-galactosamine kpatara.Ọ nwere ike belata SGPT ma weghachite ọnya cell imeju na necrosis na nkịtị.Mwepụta ethanol nke mgbọrọgwụ peony ọcha nwere ike ibelata mmụba na mkpokọta ọrụ lactate dehydrogenase na isoenzymes na oke nwere nnukwu mmerụ ahụ imeju nke aflatoxin kpatara.Mkpokọta glycosides nke paeony nwere ike igbochi mmụba nke SGPT na lactate dehydrogenase na ụmụ oke nke carbon tetrachloride kpatara, ma nwee mmetụta mgbochi na eosinophilic degeneration na necrosis nke anụ ahụ imeju.
3. Mmetụta Antioxidant: Mgbakwunye mgbọrọgwụ peony ọcha TGP nwere mmetụta antioxidant na akpụkpọ ahụ cell na-eme ka ọ dị ike, ma nwee ike inwe mmetụta na-ekpo ọkụ na radicals efu.
4. Mmetụta sistemu obi na akwara ozi mwepu nke peony nwere ike ịgbasa arịa ọbara akwara nke obi dịpụrụ adịpụ, guzogide nnukwu myocardial ischemia na oke nke pituitaryin kpatara, ma belata nguzogide vaskụla mpụta na ịbawanye mmụba ọbara mgbe etinyere ya n'ime akwara.Paeoniflorin na-enwekwa mmetụta na-agbasawanye na arịa ọbara ọbara na arịa ọbara, na-ebute mbelata nke ọbara mgbali.Nnyocha egosiwo na paeoniflorin, ihe mpụta nke mgbọrọgwụ peony ọcha, nwere mmetụta mgbochi na nchịkọta platelet na-akpata ADP na oke in vitro.
5. Mmetụta eriri afọ Mwepụta nke peony ọcha nwere mmetụta inhibitory na mkpịsị aka nke intestinal hyperexcitability nke eriri afọ na mkpụkọ nke barium chloride kpatara, mana enweghị mmetụta na mkpụkọ nke acetylcholine kpatara.Ngwakọta mmiri amịpụtara nke licorice na mgbọrọgwụ peony ọcha (0.21g) nwere mmetụta mgbochi dị ukwuu na mmegharị nke ahụ dị nro nke eriri afọ na oke bekee na vivo.Mmetụta jikọtara ọnụ nke abụọ dị mma karịa nke ma ọ bụ naanị ya, na mmetụta na-ebelata ugboro ugboro dị ike karịa mmetụta na-ebelata amplitude.Mbelata nke ntachi obi eriri afọ oke bekee 20 ruo 25 nkeji mgbe nchịkwa gasịrị bụ 64.71% na 70.59% nke ahụ na otu njikwa nkịtị, n'otu n'otu, ma sie ike karịa nke atropine (0.25 mg) na otu njikwa dị mma.Paeoniflorin nwere mmetụta inhibitory na tubes eriri afọ dịpụrụ adịpụ yana in vivo gastric motility na pigs na oke, yana oke akwara uterine dị nro, ma nwee ike imegide nkwekọrịta nke oxytocin kpatara.Ọ nwere mmetụta synergistic na Chemicalbook mmanya wepụ FM100 nke licorice.Paeoniflorin nwere mmetụta mgbochi dị ukwuu na ọnya afọ eriri afọ na oke nke mkpali na-akpata nrụgide kpatara.
6. Mmetụta ọgwụ mgbochi, analgesic na anticonvulsant.Ngwunye peony na-acha ọcha na paeoniflorin abụọ nwere mmetụta ịhịa aka n'ahụ na analgesic.Ịgbanye obere paeoniflorin n'ime ụbụrụ ventricles nke anụmanụ nwere ike ime ka ọnọdụ ihi ụra doro anya.Ngwunye intraperitoneal nke 1g/kg nke paeoniflorin sitere na mgbọrọgwụ peony na-acha ọcha na ụmụ oke nwere ike ibelata ihe omume ụmụ anụmanụ na-eme n'otu oge, ogologo oge ụra nke pentobarbital, gbochie mmeghachi omume writhing nke ụmụ oke nke ntụtụ nke intraperitoneal nke acetic acid kpatara, na iguzogide pentylenettrazole.Ihe kpatara nhụsianya.Mkpokọta glycosides nke paeony nwere mmetụta analgesic dị ịrịba ama ma nwee ike ịkwalite mmetụta analgesic nke morphine na clonidine.Naloxone anaghị emetụta mmetụta analgesic nke ngụkọta glycosides nke paeony, na-atụ aro na ụkpụrụ analgesic ya abụghị ịkpali ndị na-anabata opioid.Mwepụta nke peony nwere ike igbochi nhụsianya nke strychnine kpatara.Paeoniflorin enweghị mmetụta na akwara skeletal dịpụrụ adịpụ, yabụ a na-eche na mmetụta anticonvulsant ya bụ etiti.
7. Mmetụta na sistemu ọbara: Mwepụta mmanya Paeony nwere ike igbochi nchịkọta platelet na oke bekee nke ADP, collagen na arachidonic acid in vitro kpatara.
8. Mmetụta na usoro ahụ ji alụso ọrịa ọgụ.Mgbọrọgwụ peony na-acha ọcha nwere ike ịkwalite mmepụta nke ọgwụ mgbochi splin cell ma kwalite nzaghachi ọchị nke ụmụ oke na mkpụrụ ndụ ọbara uhie.Decoction nke ọcha peony nwere ike imegide mmetụta mgbochi nke cyclophosphamide na ọbara T lymphocytes n'ime ụmụ oke, weghachi ha n'ọkwa nkịtị, ma weghachi ọrụ nchebe cellular dị ala na nke nkịtị.Mkpokọta glycosides nke paeony nwere ike ịkwalite mmụba nke lymphocytes splenic na ụmụ oke nke concanavalin kpatara, na-akwalite mmepụta nke α-interferon na ọbara leukocytes ọbara mmadụ nke Newcastle chicken plague virus kpatara, ma nwee mmetụta bidirectional na mmepụta nke interleukin-2 na oke. splenocytes sitere na concanavalin kpatara.mmetụta na-achịkwa.
9. Mmetụta ike: Mwepụ mmanya na-acha ọcha peony nwere ike ịgbatị oge igwu mmiri nke ụmụ oke na oge nlanarị nke oke oke, ma nwee mmetụta na-ewusi ike.
10. Mgbochi mutagenic na mgbochi tumor wepụ White peony wepụ nwere ike igbochi ọrụ enzyme nke ngwakọta S9, ma nwee ike imebi metabolites nke benzopyrene ma gbochie mmetụta mutagenic ya.

11. Mmetụta ndị ọzọ (1) Mmetụta antipyretic: Paeoniflorin nwere mmetụta antipyretic na ụmụ oke nwere ahụ ọkụ artificial ma nwee ike ibelata okpomọkụ nkịtị nke oke.(2) Mmetụta na-akwalite ebe nchekwa: Mkpokọta glycosides nke paeony nwere ike imeziwanye mmụta na-adịghị mma na inweta ebe nchekwa na ụmụ oke nke scopolamine kpatara.(3) Mmetụta mgbochi hypoxic: mkpokọta glycosides nke ọcha paeony nwere ike ịgbatị oge ndụ ụmụ oke n'okpuru nrụgide nkịtị na hypoxia, belata oriri oxygen zuru oke nke ụmụ oke, ma belata ọnwụ nke ụmụ oke n'ihi nsị potassium cyanide na hypoxia.