Phosphatidylcholine imakhala ndi "mutu" wa choline ndi glycerol phospholipids.Mchira wa glycerol phospholipids ukhoza kukhala mitundu yosiyanasiyana yamafuta acids.Nthawi zambiri, mchira umodzi umakhala wodzaza ndi mafuta acid, winayo ndi unsaturated mafuta acid.Koma ena a iwo onse ndi unsaturated mafuta zidulo.Mwachitsanzo, mapapu a nyama a phosphatidylcholine ali ndi gawo lalikulu la dipalmitoyl phosphatidylcholine.
Dzina la malonda: Phosphatidylcholine PC
Dzina Lina: 1,2-diacyl-sn-glycero-3-phosphocholine, PC
Kufotokozera Kwazinthu: Zamadzimadzi / kapena zolimba: pafupifupi 60%
Ufa / granule: 10% - 98%,Zodziwika bwino 20%, 50%, 98%
Zitsanzo Zaulere: Zilipo
Maonekedwe: ufa wonyezimira wachikasu kapena wachikasu, mafuta kapena olimba
Njira Yoyesera: HPLC
Alumali Moyo: 2 years
Phosphatidylcholine imakhala ndi "mutu" wa choline ndi glycerol phospholipids.Mchira wa glycerol phospholipids ukhoza kukhala mitundu yosiyanasiyana yamafuta acids.Nthawi zambiri, mchira umodzi umakhala wodzaza ndi mafuta acid, winayo ndi unsaturated mafuta acid.Koma ena a iwo onse ndi unsaturated mafuta zidulo.Mwachitsanzo, mapapu a nyama a phosphatidylcholine ali ndi gawo lalikulu la dipalmitoyl phosphatidylcholine.
Phosphatidylcholine ndiye chigawo chachikulu cha biofilms.Gwero ndi losavuta komanso lonse.Mutha kupeza phosphatidylcholine kuchokera pafupifupi chakudya chilichonse m'moyo wanu, osati dzira yolk kapena soya.Komanso ndi lecithin mu mafuta a nyama.Mutha kupeza phosphatidylcholine mu minofu ya zomera ndi nyama.Zoonadi, kupanga malonda a phosphatidylcholine ndi mankhwala oyeretsedwa omwe ali ndipamwamba komanso zotsatira zachindunji.
Phosphatidylcholine ndi lipophilic hydrophilic mankhwala;mowa wocheperako wosungunuka mu C1 mpaka C4, wosasungunuka mu acetone ndi madzi.
Ngakhale ma PC nthawi zambiri amagwiritsidwa ntchito kuthandizira thanzi laubongo, amathanso kuthandizira kugwira ntchito kwa chiwindi ndikuwongolera kuchuluka kwa cholesterol.
Choline imatha kuwoloka chotchinga chamagazi-muubongo mosavuta kudzera muunsaturated-kulimbikitsa kufalikira kwa dongosolo, ndipo kusintha kwa plasma kungapangitse kusintha kofananako mumilingo yaubongo ya choline.
Chifukwa chosakwanira kutembenuka kwa choline kusintha ndondomeko, osati mokwanira amakhuta ndi choline gawo lapansi, choline zili mu plasma kuchuluka, amene amalimbikitsa mapangidwe acetylcholine ndi phosphorylcholine ndi kumasulidwa kwa acetylcholine.Ngati zomwe zili m'zambiri zina za phosphatidylcholine zikuwonjezeka, kutembenuka kwa choline kukhala phosphatidylcholine ndikuwonjezeka kwa nandolo kumawonjezeka.Kuchuluka kwa ma synaptic nembanemba mu ubongo kumawonjezeka.Choline imapangidwa kukhala betaine m'chiwindi, yomwe ndi njira yayikulu yosinthiranso methionine ndi S-adenosylmethionine kuti ipereke gulu la methyl.
Kagayidwe kachakudya kachiwindi kamapezeka mu cell membrane yomwe imakhala ndi masikweya mita 33,000 m'thupi la munthu.
Pali zaka zoposa 20 za mayesero a zachipatala omwe amasonyeza kuti PC imateteza chiwindi kuzinthu zoopsa zomwe zimawononga maselo, monga uchidakwa, mankhwala osokoneza bongo, zoipitsa, mavairasi ndi zotsatira zina zoopsa.
Chinthu chinanso chopangidwa ndi PC ndicho chigawo chachikulu cha nembanemba ndi mapapo, chomwe chimayendetsa pakati pa maselo kudzera mu mapuloteni otengera phosphatidylcholine (PCTP).Imagwiranso ntchito pakusintha ma cell a membrane-mediated cell ndi PCTP kuyambitsa ma enzyme ena.
Pali mfundo yosokoneza apa.Lecithin si phosphatidylcholine.Phosphatidylcholine ndi gawo lofunikira la lecithin.
Ubwino wa phosphatidylcholine
Tetezani chiwindi kuti zisawonongeke
Kupititsa patsogolo Ntchito Yachidziwitso
Kupewa zotsatira za mankhwala
Anti-aging matsenga zotsatira anawonjezera zodzoladzola
Kuwonongeka kwa lipid
Kulimbana ndi ulcerative colitis
Malingana ndi zinyama zambiri zoyesera, PC supplementation ikhoza kuonjezera acetylcholine (neurotransmitter mu ubongo), yomwe ndi muyeso wofunikira kuti ukhale wabwino kukumbukira.Maphunziro owonjezera akuchitika kuti awone zotsatira za PC ndi zakudya zina pakusintha kukumbukira kwa mbewa za dementia.Zimadziwika kuti PC ndi zakudya zina zimakhala ndi zotsatira zabwino komanso zogwira mtima, koma mayesero ambiri amafunika.Mozama, mu 2017, panali maphunziro okhudzana ndi phosphatidylcholine ndi matenda a Alzheimer's.
Chiwindi ndi chiwalo chofunikira m'thupi la munthu, ndipo zochitika zina pamoyo watsiku ndi tsiku zimatha kubweretsa mtolo waukulu pachiwindi, chomwe chimakhala chofala m'chiwindi chamafuta ndi matenda enaake.
Zakudya zamafuta ambiri zimatha kukhala ndi zotsatira zoyipa pachiwindi.Inde, chiwindi chikhozanso kuonongeka ndi poyizoni wa mowa, mankhwala osokoneza bongo, zoipitsa, mavairasi, ndi zinthu zina zapoizoni, ndipo kukonza n’kovuta kwambiri.M'zaka zapitazi za 20 za mayesero a zachipatala, kupezeka kwa phosphatidylcholine sikunachite mbali yofunika kwambiri pa njira yopulumutsira moyo.Zinganenedwe kuti zotsatira zake zimakhala zosasangalatsa, koma monga sildenafil idapangidwa kuti ipange mankhwala ochizira mtima, zotsatira zina zinapezeka m'magawo a ndondomeko ya mayesero.Kupyolera mu kufufuza mosamalitsa, titha kupeza chitetezo cha PC pachiwindi molingana ndi mphamvu ya phosphatidylcholine komanso chitetezo chake pamaselo a cell.Popeza sichikhoza kukonzedwa, ikhoza kutetezedwa pasadakhale, yomwe imakhalanso gawo lalikulu la phosphatidylcholine.
Ngakhale kuti phosphatidylcholine imagwiritsidwa ntchito ngati chakudya chowonjezera pakamwa, sichimasokoneza zinthu zake zosiyanasiyana.Malinga ndi mawonekedwe ake apadera akuthupi ndi achilengedwe, amatha kulowa mosavuta pakhungu ndikuwonjezera kutulutsa kwazinthu zina.Choncho, opanga ambiri ali okonzeka kugwiritsa ntchito phosphatidylcholine muzopakapaka zawo zakunja zosamalira khungu kuti apange zikopa zosalala komanso zonyowa.Phosphatidylcholine adawonetsanso zotsatira zabwino kwambiri pochiza ziphuphu, ndikuchepetsa 70% kwa nyengo pakadutsa masiku 28.
Phosphatidylcholine ndi molekyulu yofunikira yachilengedwe yomwe imapezeka mu cell iliyonse ya thupi la munthu.Asayansi ena ayesa mbewa zomwe zasinthidwa kuti ziwononge kuwonongeka kwa okosijeni ndikufulumizitsa ukalamba kuti aphunzire zotsatira za phosphatidylcholine pa ukalamba, kusintha kwa chidziwitso ndi kukumbukira kukumbukira odwala Alzheimer's.Zachidziwikire, asayansi ena amakhulupirira kuti kuphatikizika kwa phosphatidylcholine kuchiza matenda a Alzheimer sikunatsimikizidwe mokwanira.Koma liwiro lopanga dziko lopanda Alzheimer silingayime.Zoonadi, sitingathe kutsutsa kuti phosphatidylcholine ili ndi gawo, koma timafunikira kuyesa kowonjezereka kuti titsimikizire udindo wake.
Zotsatira zoyipa za phosphatidylcholine
Zowonetsedwa makamaka pazachipatala, zinthu zomwe zili ndi PC zomwe zili ndi chakudya zimatha kutengedwa molingana ndi malangizo;pamene ntchito mankhwala, ayenera kutsatira malangizo a madokotala ndi opanga mankhwala ntchito mankhwala.Pofuna kupewa kuopsa kwa zotsatirapo, kuyambira ndi mlingo wotsika kwambiri, mlingo waukulu umatheka pang'onopang'ono.
Oral PC ingayambitse thukuta kwambiri.Kumwa magalamu opitilira 30 patsiku kungayambitse kutsekula m'mimba, nseru, kapena kusanza.
Kulowetsa PC mwachindunji ku zotupa zamafuta kungayambitse kutupa kwakukulu kapena fibrosis.Zingayambitsenso kupweteka, kuyaka, kuyabwa, kusakhazikika kwa magazi, edema, ndi khungu lofiira
Zowonjezera pa PC zitha kugwiritsidwa ntchito mu kapisozi ndi mawonekedwe amadzimadzi popanda kulembedwa.Amaonedwa kuti ndi otetezeka akagwiritsidwa ntchito kwa nthawi yochepa monga momwe akufunira.Jekeseni wa PC ayenera kuyang'aniridwa ndi akatswiri azaumoyo.
