Dzina lazogulitsa:White Peony Extractufa
Dzina Lina:China White Blossom Extract Powder
Gwero la Botanical:Radix Paeoniae Alba
Zosakaniza:Ma glucosides a Paeonia (TGP):Paeoniflorin, Oxypaeoniflorin, Albiflorin, Benzoylpaeoniflorin
Zofotokozera:Paeoniflorin10% ~ 40% (HPLC), 1.5%Albasides, 80%Glycosides
Nambala ya CAS:23180-57-6
Mtundu: Yellow-brownufandi khalidwe fungo ndi kukoma
Mtengo wa GMOMkhalidwe: GMO Yaulere
Kulongedza: mu 25kgs fiber ng'oma
Kusungirako: Sungani chidebe chosatsegulidwa pamalo ozizira, owuma, Khalani kutali ndi kuwala kwamphamvu
Shelf Life: Miyezi 24 kuyambira tsiku lopangidwa
White Peony Extractamatanthauza m'zigawo zosakaniza yogwira peony woyera ndi njira sayansi malinga ndi luso lapadera.Malinga ndi kafukufuku wa akatswiri, zosakaniza yogwira peony Tingafinye kwa thupi la munthu ndi motere Tchati.Zinayi zofunika kwambiri ndi Paeoniflorin, Oxypaeoniflorin, Albiflorin, ndi Benzoylpaeoniflorin.
Chomera choyera cha peony chimachotsedwa muzu wouma wa Paeonia lactiflora Pall., Chomera cha banja la Ranunculaceae.Chigawo chake chachikulu ndi paeoniflorin, chomwe chingagwiritsidwe ntchito kwambiri osati m'chipatala chokha komanso m'makampani odzola.White peony Tingafinye ndi yothandiza kwambiri PDE4 ntchito inhibitor.Poletsa ntchito ya PDE4, imatha kupanga cAMP ya maselo osiyanasiyana otupa komanso chitetezo chamthupi (monga neutrophils, macrophages, T lymphocytes ndi eosinophils, etc.) kufika pamlingo wokwanira kuletsa kuyambitsa kwa maselo otupa ndikuchita zotsutsana ndi zotupa.Lilinso ndi analgesic, antispasmodic, anti-ulcer, vasodilator, kuchuluka kwa magazi m'thupi, antibacterial, chiwindi-protecting, detoxifying, anti-mutagenic, ndi anti-chotupa zotsatira.
1,2,3,6-tetragalloyl shuga, 1,2,3,4,6-pentagalloyl shuga ndi lolingana hexagalloyl shuga ndi heptagalloyl shuga anali olekanitsidwa tannin woyera peony mizu.Mulinso dextrorotatory catechin ndi mafuta osakhazikika.Mafuta osakhazikika amakhala ndi benzoic acid, peony phenol ndi zakumwa zina ndi phenols.1. Paeoniflorin: mawonekedwe a maselo C23H28O11, kulemera kwa maselo 480.45.Hygroscopic amorphous powder, [α]D16-12.8 ° (C = 4.6, methanol), tetraacetate ndi makhiristo a singano opanda mtundu, mp.196 ℃.2. Paeonol: Mawu ofanana ndi paeonol, peony mowa, paeonal, ndi peonol.Molecular formula C9H10O3, molekyulu yolemera 166.7.Makhiristo opanda mtundu onga singano (ethanol), mp.50℃, osungunuka pang'ono m'madzi, amatha kusungunuka ndi mpweya wamadzi, kusungunuka mu ethanol, etha, acetone, chloroform, benzene ndi carbon disulfide.3. Zina: Muli pang'ono oxypaeoniflorin, albiforin, benzoylpaeoniflorin, lactiflorin, latsopano monoterpene paeoniflorigenone ndi neuromuscular kutsekereza zotsatira pa mbewa, 1,2,3,4,6-Pentagalloylglucose ndi antiviral effect, gallotannin, gal-gallic asidi, ethyl gallate, tannin, β-sitosterol, shuga, wowuma, ntchofu, etc.
Ntchito:
- Anti-yotupa, antibacterial ndi antiviral zotsatira.White peony Tingafinye ali kwambiri inhibitory zotsatira dzira woyera pachimake kutupa edema mu makoswe ndipo linalake ndipo tikulephera kuchuluka kwa thonje mpira granuloma.Ma glycosides onse a paeony ali ndi anti-inflammatory and body-dependent immunomodulatory effect pa makoswe omwe ali ndi adjuvant nyamakazi.White peony kukonzekera ndi zina zopinga zotsatira pa Staphylococcus aureus, hemolytic Streptococcus, pneumococcus, Shigella dysentery, typhoid bacillus, Vibrio cholerae, Escherichia coli ndi Pseudomonas aeruginosa.Kuphatikiza apo, 1:40 decoction ya peony imatha kuletsa kachilombo ka Jingke 68-1 ndi kachilombo ka herpes.
- Mphamvu ya hepatoprotective.Chotsitsa cha peony choyera chimakhala ndi zotsatira zotsutsana kwambiri ndi kuwonongeka kwa chiwindi ndi kuwonjezeka kwa SGPT chifukwa cha D-galactosamine.Ikhoza kuchepetsa SGPT ndikubwezeretsa zotupa za maselo a chiwindi ndi necrosis kukhala yachibadwa.Kutulutsa kwa ethanol kwa mizu yoyera ya peony kumatha kuchepetsa kuchuluka kwa ntchito yonse ya lactate dehydrogenase ndi isoenzymes mu makoswe okhala ndi kuvulala kwakukulu kwa chiwindi chifukwa cha aflatoxin.Ma glycosides onse a paeony amatha kulepheretsa kuwonjezeka kwa SGPT ndi lactate dehydrogenase mu mbewa zomwe zimayambitsidwa ndi carbon tetrachloride, ndipo zimakhala ndi zotsatira zotsutsana ndi kuchepa kwa eosinophilic ndi necrosis ya chiwindi.
- Antioxidant effect: White peony root extract TGP ili ndi antioxidant ndi cell membrane stabilizing effect, ndipo ikhoza kukhala ndi scavenging effect pa free radicals.
- Zotsatira za dongosolo la mtima ndi mitsempha yoyera ya peony imatha kukulitsa mitsempha yamagazi yapamtima pawokha, kukana pachimake myocardial ischemia mu makoswe omwe amayamba chifukwa cha pituitaryin, komanso kuchepetsa kukana kwa mitsempha yamagazi ndikuwonjezera kutuluka kwa magazi akabayidwa mumtsempha.Paeoniflorin imakhalanso ndi mphamvu yochepetsera mitsempha yamagazi ndi mitsempha yamagazi, ndipo imayambitsa kuchepa kwa magazi.Kafukufuku wawonetsa kuti paeoniflorin, chochokera ku mizu yoyera ya peony, imalepheretsa kuphatikizika kwa mapulateleti a ADP mu makoswe mu vitro.
- M'mimba zotsatira White peony Tingafinye ali chopinga kwambiri pa mowiriza chidule cha m'mimba hyperexcitability ndi mgwirizano chifukwa barium kolorayidi, koma alibe mphamvu pa mgwirizano chifukwa cha acetylcholine.Kusakaniza kwamadzi kwa licorice ndi mizu yoyera ya peony (0.21g) kumalepheretsa kwambiri kuyenda kwa matumbo osalala a akalulu mu vivo.Zotsatira zophatikizana za ziwirizi ndi zabwino kuposa zomwe zili zokha, ndipo mphamvu yochepetsera pafupipafupi imakhala yamphamvu kuposa mphamvu yochepetsera matalikidwe.Kuchepa kwa kalulu m'mimba kutsekemera kwafupipafupi 20 kwa mphindi 25 pambuyo pa makonzedwe kunali 64.71% ndi 70.59% ya gulu lolamulira bwino, motero, ndipo linali lamphamvu kuposa la atropine (0.25 mg) mu gulu lolamulira labwino.Paeoniflorin imakhala ndi zoletsa pamachubu a matumbo akutali komanso mu vivo chapamimba motility mu nkhumba ndi makoswe, komanso minofu yosalala ya makoswe, ndipo imatha kuletsa kutsekeka komwe kumachitika chifukwa cha oxytocin.Ili ndi synergistic kwenikweni ndi Chemicalbook mowa Tingafinye FM100 wa licorice.Paeoniflorin imalepheretsa kwambiri zilonda zam'mimba mu makoswe omwe amachititsidwa ndi zosokoneza.
- Sedative, analgesic, ndi anticonvulsant zotsatira.Jekeseni woyera wa peony ndi paeoniflorin onse ali ndi sedative komanso analgesic zotsatira.Kubaya paeoniflorin pang'ono m'mitsempha yaubongo ya nyama kungayambitse kugona.Jekeseni wa intraperitoneal wa 1g/kg wa paeoniflorin wochokera ku mizu yoyera ya peony mu mbewa amatha kuchepetsa zochita za nyama zokha, kutalikitsa nthawi yogona ya pentobarbital, kulepheretsa mbewa zomwe zimachitika chifukwa cha jakisoni wa intraperitoneal wa acetic acid, ndikukana pentylenetetrazole.Zoyambitsa kukomoka.Ma glycosides onse a paeony ali ndi zotsatira zochepetsera ululu ndipo amatha kupititsa patsogolo zotsatira za morphine ndi clonidine.Naloxone sichimakhudza zotsatira za analgesic za glycosides onse a paeony, kutanthauza kuti mfundo yake ya analgesic si yolimbikitsa opioid receptors.Kutulutsa kwa peony kumatha kuletsa kugwedezeka komwe kumachitika chifukwa cha strychnine.Paeoniflorin alibe mphamvu pa olekanitsidwa chigoba minofu, kotero n'zosadabwitsa kuti anticonvulsant zotsatira zake ndi chapakati.
- Mphamvu pamagazi: Kutulutsa kwa mowa wa Paeony kumatha kuletsa kuphatikizika kwa mapulateleti mu akalulu opangidwa ndi ADP, collagen, ndi arachidonic acid mu vitro.
- Mmene chitetezo cha m'thupi.Mizu yoyera ya peony imatha kulimbikitsa kupanga ma spleen cell antibodies ndikuwonjezera kuyankha kwa mbewa ku maselo ofiira amagazi.White peony decoction akhoza antagonize inhibitory zotsatira za cyclophosphamide pa zotumphukira magazi T lymphocytes mu mbewa, kuwabwezeretsa bwinobwino misinkhu, ndi kubwezeretsa otsika ma chitetezo ntchito mwakale.Ma glycosides onse a paeony amatha kulimbikitsa kuchuluka kwa ma splenic lymphocytes mu mbewa zomwe zimayambitsidwa ndi concanavalin, kulimbikitsa kupanga α-interferon mu chingwe chamagazi chamunthu chomwe chimayambitsidwa ndi kachilombo ka Newcastle chicken plague virus, komanso kukhala ndi zotsatirapo ziwiri pakupanga interleukin-2 mu makoswe. splenocytes opangidwa ndi concanavalin.kuwongolera zotsatira.
- Kulimbikitsa: White peony mowa Tingafinye akhoza kutalikitsa nthawi kusambira mbewa ndi hypoxic kupulumuka nthawi ya mbewa, ndipo ali ndi kulimbikitsa kwenikweni.
- Anti-mutagenic ndi odana ndi chotupa zotsatira White peony Tingafinye akhoza kusokoneza enzyme ntchito ya osakaniza S9, ndipo akhoza inactivate metabolites wa benzopyrene ndi ziletsa ake mutagenic kwenikweni.
11. Zotsatira zina (1) Antipyretic effect: Paeoniflorin ali ndi antipyretic kwenikweni pa mbewa ndi malungo opangira ndipo akhoza kuchepetsa kutentha kwa thupi la mbewa.(2) Kupititsa patsogolo kukumbukira: Ma glycosides onse a paeony amatha kusintha kusaphunzira bwino komanso kukumbukira kukumbukira mu mbewa zomwe zimayambitsidwa ndi scopolamine.(3) Anti-hypoxic effect: Ma glycosides onse a white paeony amatha kutalikitsa nthawi yopulumuka ya mbewa pansi pa kupanikizika kwabwino ndi hypoxia, kuchepetsa kugwiritsira ntchito mpweya wa mbewa, ndi kuchepetsa imfa ya mbewa chifukwa cha poizoni wa potaziyamu cyanide ndi hypoxia.