Product Name:Syringae Cortex Extract

Rimwe Zita: Japanese lilac (syringa reticulata);Syringa reticulata amurensis;Syringa reticulata amurensis;Syringa reticulata (Bl.)Hara var.mandshurica (Maxim.) Hara

Botanic Source:Syringae Cortex Bark

Zita reLatin:Syringa reticulata (Blume) Hara var.amurensis (Rupr.) Pringle

Assay:Eleutheroside b, Oleuropein

Nhamba yeCAS:118-34-3, 32619-42-4

Ruvara: Yellow-brown powder ine hunhu hwemunhuwi uye kuravira

Tsanangudzo:Eleutheroside b5%+Oleuropein 20%;Eleutherosideb 8%+Oleuropein 35%;Eleutherosideb 10%;Eleutheroside b 98%;

GMO Mamiriro:GMO Yemahara

Kurongedza: mune 25kgs fiber zvigubhu

Kuchengeta: Chengetedza mudziyo usina kuvhurwa munzvimbo inotonhorera, yakaoma, Chengetedza kure nechiedza chakasimba

Sherufu Hupenyu: Mwedzi makumi maviri nemana kubva pazuva rekugadzirwa

Syringae Folium (SF), inocherechedzwa muChinese Pharmacopeia, yakashandiswa mumishonga yemakwenzi kurapa zvirwere zvinoputika uye yaibvisa mvura yeSF, Yanlixiao (YLX) inova kugadzirira kwekutengesa mushonga wechinyakare weChinese mushonga wakashandiswa zvakanyanya kukiriniki kurwisa kuzvimba kwematumbo.Kuti uongorore hwaro hwayo hwekurapa hweSF, chikamu chinoshanda kubva kuSF (ESF) chakawanikwa nebio-inotungamirwa yekuzviparadzanisa uye hupfumi hwezvinhu zvinoshanda.Mutsvagiridzo iyi, ESF yakaonekwa sechikamu chinopesana nekuputika nekuenzanisa chiyero chekupona kweLPS-induced kuzvimba mbeva modhi.Iyo in vivo anti-inflammation efficacy yeESF yakawedzera kuedzwa nembeva nzeve edema modhi.Zvikamu gumi neshanu zveESF zvakapatsanurwa kubva kuESF mushure mekuzivikanwa neUPLC-TOF-MS, uye inhibition yavo pa lipopolysaccharide (LPS) -induced nitric oxide (NO) kugadzirwa kwakaedzwa pamwe neESF muRAW 264.7 macrophages cell line.Iine chinangwa chekutsvaga maitiro ayo ekudzivirira-kuzvimba, iyo network pharmacology yekudzidza yakaitwa zvichibva pane zvakakosha zvinoshanda zvikamu.Semhedzisiro, ESF yakawanikwa nekubudirira kuri nani mukudzivisa kuzvimba nzeve (82.2 mg / kg, 43.7%) kana ichienzaniswa neYLX (293.3 mg / kg, 37.9%).Zvichakadaro, zvikamu zvikuru zveESF, luteolin uye quercetin zvakawanikwa zvine simba guru mukuderedza NO kugadzirwa kana ichienzaniswa neaminoguanidine (positive control) (81.3%, 78.7% uye 76.3%, maererano, 50 μg / ml).Ongororo yetiweki pharmacology yakaratidzawo kuti luteolin nequercetin zvinogona kuve zvakakosha zveiyo anti-inflammation chiitiko cheESF, uye NFKB1, RELA, AKT1, TNF uye PIK3CG zvakaonekwa sezvinangwa zvakakosha uye MAPK, NF-κB, TCR uye kusaina kweTLRs. nzira dzinogona kubatanidzwa mukurwisa-kuzvimba chiito cheESF.Mhedzisiro yakawanikwa muchidzidzo ichi yakaratidza kuti ESF yaive nemukana wekuvandudzwa senge anti-inflammation agent inoshandiswa mukiriniki.

Syringae Cortex Extract chigadzirwa chakaumbwa chakatorwa kubva kuSyringa reticulata, uye zvimisikidzo zvayo zvikuru iEleutheroside b neOleuropein.

Eleutheroside iboka remakomisheni akasiyana akaparadzaniswa kubva kumidzi yeAcanthopanax senticosus, inotengeswa zvakanyanya muzvinyorwa.Eleutheroside B (syringin) ndeye phenyl propyl glycosides inogona kushandiswa seChinese mishonga yekugadzirira uye kudya kwekuwedzera kweEleutherococcus senticosus.

Oleuropein ndeye glycosylated yechipiri iridoid komboni, inova inovava phenolic kompani inowanikwa mugirinhi maorivhi svuura, pulp, mbeu, uye mashizha.Inowanzo kuwanikwa mumaorivhi, asi kune zvakare chikamu chesyringae cortex pamusoro pekuvapo kwayo, iyo pasina mubvunzo inopa syringae cortex inobvisa ine mhedzisiro yakakura.