Magaca Alaabta:Soosaar Sinjibiil Madow
Isha dhirta:Kaempferia parviflora.L
CASNo:21392-57-4
Magac kale:5.7-Dimethoxyflavone
Tilmaamaha: 5.7-Dimethoxyflavone ≥2.5%
Wadarta Flavonoids ≥10%
Midabka:Purplebudo leh ur sifo iyo dhadhan
GMOXaalada:GMO Bilaash
Xirmooyinka: 25kgs durbaannada fiber-ka
Kaydinta: Weelka ha furin meel qabow oo qalalan, ka fogow iftiinka xooggan
Life Life:24 bilood laga bilaabo taariikhda wax soo saarka
5,7-Dimethoxyflavone waa mid ka mid ah qaybaha ugu muhiimsan ee Kaempferia parviflora, kaas oo leh cayilka lidka ku ah, anti-bararka, iyo saamaynta anti-buro.5,7-Dimethoxyflavone waxay joojisaa cytochrome P450 (CYP) 3As.5,7-Dimethoxyflavone sidoo kale waa borotiin wax ku ool ah oo ka hortaga kansarka naasaha (BCRP).
Waxqabadka Vitro:
Dhaqdhaqaaqa ugu fiican ee vitro trypanocidal ee T. brucei rhodesiense waxaa sameeyay 7,8-dihydroxyflavone (50% xoojinta xakameynta [IC50], 68 ng / ml), oo ay ku xigto 3-hydroxyflavone, rhamnetin, iyo 7,8,3′, 4'-tetrahydroxyflavone (IC50s, 0.5 microg/ml) iyo catechol (IC50, 0.8 microg/ml)
Waxqabadka Vivo:
5,7-Dimethoxyflavone (10 mg/kg, afka, hal mar maalintii, 10 maalmood) waxay yarayn kartaa heerarka muujinta CYP3A11 iyo borotiinnada CYP3A25 ee beerka jiirarka [1].
5,7-Dimethoxyflavone (25 iyo 50 mg / kg, afka) waxay joojin kartaa sarcopenia ee jiirarka waayeelka ah [3].
5,7-Dimethoxyflavone (50 mg/kg/d, afka, waarta toddobaadyada 6) waxay yarayn kartaa korodhka miisaanka oo waxay joojin kartaa beerka dufanka leh ee jiirarka HFD [5].
MCE si madaxbanaan uma aysan xaqiijin saxnaanta hababkan.Waxay yihiin tixraac kaliya.
