Magaca Alaabta:Syringae Cortex Extract

Magac kale: Lilac Japanese (syringa reticulata);Syringa reticulata amurensis;Syringa reticulata amurensis;Syringa reticulata (Bl.)Hara var.mandshurica (Maxim.) Hara

Isha Botanic:Syringae Cortex Bark

Magaca Laatiinka:Syringa reticulata (Blume) Hara var.amurensis (Rupr.) Pringle

Qiimayn:Eleutheroside b, Oleuropein

CAS Maya:118-34-3, 32619-42-4

Midabka: budo jaale-brown leh oo leh ur iyo dhadhan sifo

Faahfaahin:Eleutheroside b5%+Oleuropein 20%;Eleutherosideb 8%+Oleuropein 35%;Eleutherosideb 10%;Eleutheroside b 98%;

Xaalada GMO:GMO Bilaash

Xirmooyinka: 25kgs durbaannada fiber-ka

Kaydinta: Weelka ha furin meel qabow oo qalalan, ka fogow iftiinka xooggan

Life Life:24 bilood laga bilaabo taariikhda wax soo saarka

Syringae Folium (SF), oo lagu xusay Pharmacopeia Shiinaha, ayaa loo isticmaalay dawooyinka geedaha si loogu daweeyo cudurrada caabuqa iyo biyaha laga soo saaro SF, Yanlixiao (YLX) oo ah diyaarin ganacsi dawo dhaqameed Shiinees ah ayaa si weyn loogu isticmaalay kiliinikada ka hortagga caabuqa mindhicirka.Si loo sahamiyo aasaaskeeda agabka daawaynta ee SF, jajab wax ku ool ah oo ka yimid SF (ESF) ayaa lagu ogaaday go'doominta noole hagaya iyo kobcinta qaybaha firfircoon.Cilmi-baadhistan, ESF waxaa loo aqoonsaday inay tahay jajab ka-hortagga-bararka iyadoo la barbardhigay heerka badbaadada ee moodeelka bararka ee ay keentay LPS.In vivo waxtarka ka-hortagga caabuqa ee ESF waxaa sii tijaabiyay qaabka bararka dhegta jiirka.Shan iyo toban qaybood oo waaweyn oo ESF ah ayaa laga soocay ESF ka dib markii la aqoonsaday UPLC-TOF-MS, iyo xannibaaddooda lipopolysaccharide (LPS) -soosaarka nitric oxide (NO) ayaa lagu tijaabiyay ESF ee RAW 264.7 khadka unugyada macrophages.Ujeeddada raadinta hababka ka hortagga caabuqa, daraasadda dawooyinka shabakadaha ayaa la sameeyay iyadoo lagu saleynayo qaybaha ugu muhiimsan ee firfircoon.Natiijooyinka, ESF waxaa lagu helay waxtarka wanaagsan ee joojinta bararka dhegta (82.2 mg / kg, 43.7%) marka la barbardhigo YLX (293.3 mg / kg, 37.9%).Dhanka kale, qaybaha ugu muhiimsan ee ESF, luteolin iyo quercetin ayaa lagu helay waxtarka muhiimka ah ee yaraynta wax soo saarka NO marka la barbar dhigo aminoguanidine (xakamaynta togan) (81.3%, 78.7% iyo 76.3%, siday u kala horreeyaan, 50 μg / ml).Falanqaynta dawooyinka shabakada ayaa sidoo kale soo jeediyay in luteolin iyo quercetin ay noqon karaan qaybaha muhiimka ah ee dhaqdhaqaaqa ka hortagga caabuqa ee ESF, iyo NFKB1, RELA, AKT1, TNF iyo PIK3CG ayaa loo aqoonsaday inay yihiin bartilmaameedyada muhiimka ah iyo MAPK, NF-κB, TCR iyo TLRs. Wadooyinka ayaa laga yaabaa inay ku lug yeeshaan ficilka ka hortagga bararka ee ESF.Natiijooyinka laga helay daraasaddan waxay muujiyeen in ESF ay awood u leedahay in loo horumariyo sidii wakiilka ka-hortagga bararka ee laga codsado rugta caafimaadka.

Syringae Cortex Extract waa badeecad isku dhafan oo laga soo saaray Syringa reticulata, maaddooyinka ugu muhiimsanna waa Eleutheroside b iyo Oleuropein.

Eleutheroside waa koox ka kooban xeryahooda kala duwan oo ka go'doonsan xididada Acanthopanax senticosus, ganacsi ahaan inta badan lagu iibiyo soosaarayaasha.Eleutheroside B (syringin) waa phenyl propyl glycosides oo loo isticmaali karo diyaarinta dhirta Shiinaha iyo kaabista cuntada ee Eleutherococcus senticosus.

Oleuropein waa unug glycosylated sare iridoid, kaas oo ah xarun phenolic qadhaadh oo ka jirta diirka saytuunka cagaaran, saxarka, miraha, iyo caleemaha.Badanaa waxaa laga helaa saytuun, laakiin sidoo kale waxaa jira qayb ka mid ah kiliyaha saliingaha ee ku saabsan jiritaankeeda, kaas oo shaki la'aan bixiya kiliyaha saliingaha oo leh saameyn la taaban karo.