Igama lemveliso:I-pinoquinoline quinone shremium yetyuwa
Inombolo ye-CAS: 122628-50-50-50 / 72909-3
Ubunzima bemolekyuli: 374.17 / 330.21
Ifomula ye-Molecroula: c14h4n2n3o2o8 / c14h6N2N2O8
Ukucaciswa: I-PQQ ye-PQQ Ityheli ye-99%; pqq acid i-99%
Inkangeleko: i-orenji ebomvu ebomvu kwi-reddish brown powder.
Isicelo: Isetyenziselwa ngokubanzi ukongeza kunye nezixhobo zesondlo.
Ukugcinwa: Igcinwe kwimeko ehlaziyiweyo kwaye eyomileyo, yiba kude nelanga.
I-Pyraloquinequinoline Quindone Shoodium yeTyuwayiti (PQQ) Inkcazo yeMveliso
Amagqabantshintshi ngemveliso
I-Pyreraquinequinoline Quindone Ityheli (I-CASS HAYI: 122628-50-50-50-50-50), iqhelekile i-PQQ ye-PQQ, i-bioquinequinoline ye-pinequinoline-i-Resox cofactor ye-Antioxridant Proceridant ye-Antioxididant ye-Antioxridant yepropathi. Ngokwemvelo ifunyenwe emhlabeni, i-Kiwoirt, ukutya okugxothiweyo, kunye nobisi lwebele loluntu, i-PQQ idlala indima ebalulekileyo ekuveliseni amandla e-itocondy. Ngaphezulu kwe-80% yezongezo zokutya ezisebenzisa le fomu yetyuwa yesodium ngenxa yozinzo oluphuculweyo kunye nokuluka.
Izibonelelo eziphambili
- Ukuphucula amandla eeselfowuni: Ukuxhasa i-mitochoreenish biogenesis, ukuphucula amandla imetabolism kunye nokunciphisa ukudinwa.
- Inkxaso yokuqonda
- I-Cardiovascular Impilo: Ukunciphisa uxinzelelo lwe-oxidative kwaye ixhasa ukusebenza kwentliziyo ngeendlela ze-antioxidant.
- I-Antioxidant ye-Antioxidant: Ayithathi qhinga simahla kwaye uphinde usebenzise i-antiocunts anexidants efana neGlutathione, ukukhuthaza impilo yeselula ngokubanzi.
Inzululwazi yesayensi
- Imeko ye-FDA ye-FDA: iqatshelwe njengokuchongwa ngokubanzi njengoko ikhuselekile (i-GRAs) nge-US FFDA ukuze isetyenziswe ekutyeni nezongezelelo.
- Imvume ye-EFSA: kuvavanywa ngokhuseleko phantsi kweMvumelwano yokutya e-EU IONTS (EU 2015/283), kwiimeko ezithile zokusetyenziswa.
- Izifundo zeklinikhi: Ukubonisa ukusebenza ngokuphucula ukusebenza kwengqondo, ukunciphisa uxinzelelo lwe-oxidatives, kunye nokuphucula ukusebenza kwe-mitochond kwizilingo zabantu.
Inkcazo yobugcisa
| Ipropathi | Iinkcukacha |
|---|---|
| Ifomula yemolekyula | C₁₄h₄n₂na₂o₈ |
| Ubunzima bemolekyuli | 374.17 g / mol |
| Imbonakalo | I-reddish-brown powder |
| Ubunyulu | ≥98% (HPLC) |
| Ukunyibilikisa | Inyibiliki yamanzi (i-3 g / l nge-25 ° C) |
| Ukugcinwa | Gcina kwindawo eyomileyo, epholileyo (2-8 ° C kuyacetyiswa); Kulumkele ukukhanya kunye nokufuma. |
Ukusetyenziswa kwakhona
- Umthamo: I-10 ukuya kwi-10 ukuya kwi-MG / usuku lwabantu abadala. Abaqalayo kufuneka baqale nge-10 ukuya kwi-20 mg kwaye bahlengahlengise ngokusekwe kwimpendulo.
- Ifomu: Ifanelekile kwiicapsules, amacwecwe, kunye nokudityaniswa kwe-powded. Ihambelana ne-vegan kunye ne-gluten-free.
Ukuqinisekisa umgangatho
- Izatifikethi: yenziwe phantsi kwenqanaba le-HACCP kunye ne-ISO, ukuqinisekisa ukhuseleko kunye nokulandelela.
- I-NO-GMO: Iveliswe nge-Fersation isetyenziswa ngokungekho mfuziseloI-Hyphomicrobim Denitififuns.
Ukuthobela umthetho
- Izithintelo zemakethi ye-EU: Ayigunyaziswanga ngoku ukuthengisa kwi-EU, e-UK, i-Iceland, i-Liechtenstein, okanye iSwitzerland ngaphandle kwemvume yangaphambili.
- Iimfuneko zelebheli: iimveliso kufuneka zibandakanye:
- "Ngabantu abadala kuphela. Ayikhuthazwanga kubafazi abakhulelwe okanye bakhuthaze.".
- "I-Pyraquinoline Quindone Shutodium ityuwa"njengegama elichongiweyo.
Izicelo
- Inkxaso-mali yokutya: Ii-boosters ezinamandla, ukuphucula ukuqonda, kunye neefomu ezichasene ne-anting.
- Ukutya okusebenza
- I-cosmetics: isetyenziswe njengolusu oluzikhuselayo kwiikhrim ezinamandla.
Kutheni ukhetha i-PQQ yethu?
- Ucoceko oluphezulu: ≥98%
- Ukuthobela umhlaba: Isikhokelo esineenkcukacha kwimigaqo ethile yentengiso.
- Inkxaso yophando: ixhaswa ngabantu abangaphezu kwe-20 yoontanga ngokhuseleko kunye nokusebenza kakuhle.
Qhagamshelana nathi
Kwixabiso le-bulk, izatifikethi zohlalutyo, okanye uncedo lolawulo, ukufikelela kwiqela lethu lentengiso. Sibonelela ngezisombululo ezimbi zokufezekisa iimfuno zakho zokwakha.
Imithombo yokutya yePyraquineline Quindone
I-PQQ yendalo ikhona kwi-RECY SOFT
G.I-Hait yafumanisa ukuba yayiyinto yesithathu ye-redox kwi-bacteria emva kweNikovin kunye neFlavin (nangona wayecinga ukuba yayinguNaphthoquinone). UAnthony noZatman bafumana i-redotors engaziwayo kwi-ethanol defdegenase. Ngo-1979, iSalisbury kunye noogxa bakhe kunye neDueine kunye nabalingane babo basungula esi siseko se-pseudo ukusuka kwi-methanol defdegel UAdachi kunye noogxa bakhe bafumanisa ukuba i-acetobacter iqulethe i-PQQ.
I-Mechasm yeNkqubo yePyreraquinequinequineline Quinene
I-Pyraquinoline Quindone (PQQ) yimolekyuli encinci, enesiphumo se-resox, inokunciphisa i-oxidant (i-antioxidant); Ibuyiselwe kwifom esebenzayo nguGlutathione. Kubonakala ngathi kunokwenzeka kuba kungazinza amawaka emijikelezo ngaphambi kokuphela, kwaye kuyinto entsha kuba inxulumene nomenzi weeseli zeproteni (i-antiotenoids efana ne-AntioXanthin, iphakathi kwe-astaxanthin, apho badlala khona inani elithile le-antioxidant). Ngenxa yokusondela, i-PQQ ibonakala ngathi idlala indima kufutshane neeproteni ezinje ngee-carotenoids kwi-membrane yeseli.
Le misebenzi ye-resox inokutshintsha imisebenzi yeproteyini kunye nendlela yokuhambisa umqondiso. Nangona zininzi izifundo ezithembisayo kwi-vitro (iimodeli zangaphandle zokuphila), ezinye iziphumo ezithembisayo ze-PQQ ezongeziweyo zihambelana ngokuguqula iindlela zokutshintsha kwendlela okanye izibonelelo zazo kwi-mitochondria. (Velisa ngaphezulu kwaye uphucule ukusebenza).
Ngu-coennyme kwi-bacteria (ke ngenxa yebacteria, ifana ne-B-Vitamins), kodwa ayibonakali ngathi yandisa ebantwini. Kuba oku kungasebenzi nakubantu, inqaku lendalo ngo-2003, ijenali yesayensi, ivakalisa ukuba i-PQ ye-PQ yicandelo le-vitamin liphelelwe lixesha kwaye litshatile.
Mhlawumbi eyona nto ibalulekileyo sisiphumo se-PQQ kwi-mitochondria, ebonelela ngamandla (i-ATP) kunye nokulawula i-metabolism yeseli. Abaphandi bajonga kakhulu ifuthe le-PPQ kwi-mitochondria kwaye bafumanisa ukuba i-PQQ inokunyusa inani le-mitochondria kwaye iphucule ukusebenza kwe-mitochondria. Esi sisizathu esibalulekileyo se-PPQ kuluncedo kakhulu. I-enzymes equkethe i-PQQ yaziwa njengeGlucose Dehydroight, iprotein ye-quinoa esetyenziswa njengesixhobo se-glucose.
Izibonelelo zePyraquinoline Quinene
Ukuba ne-mitochondria kwiyona nto ibaluleke kakhulu kubomi obunempilo onokuthi ube namava izibonelelo ezininzi ngelixa uthatha i-PPQ. Nazi ezinye zezinto ezibalulekileyo malunga nePyrequinequinequinedine Quindone.
Ukunyusa amandla eseli
Kuba i-mitochondria ivelisa amandla eeseli, kunye ne-PQQ inceda umsebenzi we-mitochondria ngokufanelekileyo, amandla kwiiseli akhula apha ewonke; Le yinkqubo ye-pyraquinequinedine xione mitnism yendlela. Amandla angasetyenziswayo ephambukisiwe kwamanye amalungu omzimba. Ukuba umzimba wakho awunamanzi imini yonke, okanye uziva udiniwe okanye unxilile, ke amandla amaninzi e-PPQ ebaluleke kuwe. Olunye uphando lufumanise ukuba emva kokuthatha i-PQQ, izifundo ngeengxaki zamandla axeliweyo babenamanqanaba asezantsi kakhulu okudinwa. Ukuba ufuna into yokwandisa amandla akho, i-PQQ inokukunceda ngaloo nto.
Ukuthintela ukwehla kwengqondo
Ngophuhliso lwesayensi, izazinzulu zifumanise ukuba into yokukhula ye-nerve (i-NGF) inokukhula kwaye iphinde ifumane kwakhona. Kwangelo xesha, i-PQQ ibonisiwe ukuba inefuthe elihle kwi-NGF kunye nokwandisa ukukhula kwethambo ngamaxesha angama-40. I-NGF ibalulekile ekuqulunweni nasekugcinweni kwee-neurons ezintsha, kwaye inokubuyisela ii-neurons ezonakalisiweyo ezinokuthintela ukusebenza kwengqondo. Ii-neurons ziiseli ezidlulisela ulwazi, ngoko ke ubungangamela bunako ukunxibelelana phakathi kwabo kunye namanye amalungu omzimba. Ukuphucula umgangatho kunye nenani lee-neurons ezinokuphucula ulwazi. Ke, i-PQQ inophuculo lwexesha elifutshane.
Ukuxhasa i-Cardiovascular Impilo
I-Pyraquinoline Quinine ibonelela ngenkxaso ye-AntioCioxidant kunye ne-mitochondIalm. Izifundo zibonise ukuba zombini i-PQQ kunye neCOQ10 inkxaso yeMvocardial Umsebenzi kunye nokusetyenziswa ngokufanelekileyo kwe-weasigen efanelekileyo. I-Pyraquinoline Quinene ithintela uxinzelelo lwe-oxidage ngokutsha.
Okunye ukusebenza kakuhle:
Ngaphandle kwezi zibonelelo zithathu ziphambili ezidweliswe apha ngasentla, i-PQQ inikezela ngezinye izibonelelo ezingaziwayo. I-PQQ ingadlala indima ekupheliseni ukuvuvukala komzimba, ngcono ubuthongo bakho kwaye inokuphucula ukuchuma, kodwa kuyafuneka ngakumbi kuphando oluchazayo. Njengoko uphando luqhubela phambili, izibonelelo ezininzi zokuthatha i-PQQ zinokufunyanwa.
Umthamo wePyraquinequinedineline Quinene
Okwangoku, akukho rhulumente okanye ngubani oye wachaza i-pyreraquinequinedine quinone quinone. Nangona kunjalo, abanye abantu kunye namaziko benze iimvavanyo ezininzi zebhayiloji kunye novavanyo lomntu kwi-dosage efanelekileyo ye-Pyreloquinequinoline Powder. Ngokujonga kunye nokuthelekisa intsebenzo yomzimba yezifundo, kugqitywa ukuba i-dosage efanelekileyo ye-PQQ yi-20 mg-50 mg. Soloko udlulisela ugqirha wakho ukuba ikhona imibuzo elinde. Njenge-bioproqq pyrandequineline ye-quoodium yetyuwa.
Iziphumo ebezingalindelekanga zePQQ
Ukusukela ngo-2009, izongezo zokutya eziqulathiweyo ze-PQQ Na 2 zithengisiwe kwiSaziso se-United States emva kolawulo lokutya kunye nolawulo lweziyobisi (i-FDA), kwaye akukho nto iphambili ekuxeliweyo. Ukuba ufuna ukongeza i-Pyrequinequinequineline Quinene kwi-Quinene kwi-fune yakho yokutya, kubalulekile ukukhumbula into enye. Kuba ayifuni kakhulu i-PQQ ukuvelisa isiphumo, iidosi ezininzi zigcinwa kuluhlu oluncinci. Ke ngoko, uninzi lwabantu akufuneki bakhathazeke ngayo nayiphi na imiphumela ye-pyraquinequinedineline quinene. (Yilo nto oyithengileyo i-pyraquinequinoline quinone pqq eyongeziweyo kwimarike)
