Igama:CDP-CHOLINE,CITICOLINE
Igama leKhemikhali: cytidine5'-diphosphatecholine
Ifomula yeemolekyuli:C14H26N4O11P2
CAS:987-78-0
Einecs NO: 213-580-7
Ubunzima befomula: 488.33
Imbonakalo: Umgubo omhlophe ngaphandle.
Ubunyulu: 98%
Igama leKhemikhali: cytidine5'-diphosphatecholine
Ifomula yeemolekyuli:C14H26N4O11P2
CAS:987-78-0
Einecs NO: 213-580-7
Ubunzima befomula: 488.33
Imbonakalo: Umgubo omhlophe ngaphandle.
Ubunyulu: 98%
I-Citicoline (INN), eyaziwa ngokuba yi-cytidine diphosphate-choline (CDP-Choline) okanye i-cytidine 5′-diphosphocholine i-nootropic.Iphakathi kwisizukulwana se-phosphatidylcholine esivela kwi-choline.
Uphononongo lucebisa ukuba izongezo ze-CDP-choline zonyusa uxinzelelo lwe-dopamine receptor, kwaye zicebisa ukuba i-CDP-choline supplementation inceda ukuthintela ukonakala kwememori okubangelwa ziimeko ezimbi zokusingqongileyo.Uphando lokuqala lufumene ukuba izongezelelo ze-citicoline zinceda ukuphucula ukugxila kunye namandla engqondo kwaye zinokuba luncedo kunyango lwengxaki yokusilela.
I-Citicoline nayo ibonakaliswe ukuphakamisa i-ACTH ngokuzimeleyo kumanqanaba e-CRH kunye nokukhulisa ukukhululwa kwamanye amahomoni e-axis e-HPA afana ne-LH, i-FSH, i-GH kunye ne-TSH ekuphenduleni izinto zokukhupha i-hypothalamic.Ezi ziphumo kumanqanaba e-hormone ye-HPA zinokuba luncedo kwabanye abantu kodwa zinokuba nemiphumo engathandekiyo kulabo abaneemeko zonyango ezibandakanya i-ACTH okanye i-cortisol hypersecretion kuquka i-PCOS, uhlobo lwe-II yeswekile kunye nengxaki enkulu yokudakumba.
Uphononongo lucebisa ukuba izongezo ze-CDP-choline zonyusa uxinzelelo lwe-dopamine receptor, kwaye zicebisa ukuba i-CDP-choline supplementation inceda ukuthintela ukonakala kwememori okubangelwa ziimeko ezimbi zokusingqongileyo.Uphando lokuqala lufumene ukuba izongezelelo ze-citicoline zinceda ukuphucula ukugxila kunye namandla engqondo kwaye zinokuba luncedo kunyango lwengxaki yokusilela.
I-Citicoline nayo ibonakaliswe ukuphakamisa i-ACTH ngokuzimeleyo kumanqanaba e-CRH kunye nokukhulisa ukukhululwa kwamanye amahomoni e-axis e-HPA afana ne-LH, i-FSH, i-GH kunye ne-TSH ekuphenduleni izinto zokukhupha i-hypothalamic.Ezi ziphumo kumanqanaba e-hormone ye-HPA zinokuba luncedo kwabanye abantu kodwa zinokuba nemiphumo engathandekiyo kulabo abaneemeko zonyango ezibandakanya i-ACTH okanye i-cortisol hypersecretion kuquka i-PCOS, uhlobo lwe-II yeswekile kunye nengxaki enkulu yokudakumba.
Isatifiketi sokuHlalutya
| Ulwazi lweMveliso | |
| Igama lemveliso: | Citicoline(CDP-Choline) |
| Inombolo yeCAS: | 987-78-0 |
| Ifomula yemolekyuli: | I-C14H26N4O11P2 |
| Inombolo yeqela. | I-TRB-CDP-20190620 |
| Umhla weMFG: | NgoJuni 20,2019 |
| Into | Inkcazo | Iziphumo zovavanyo |
| Izithako ezisebenzayo | ||
| Isivavanyi(%.Kwisiseko esomileyo) | 98.0% ~ 102.0% yi-HPLC | 100.30% |
| Ulawulo Lomzimba | ||
| Imbonakalo | Umgubo ococekileyo wekristale | Iyahambelana |
| Umbala | Mhlophe ukuya kuMhlophe | Iyahambelana |
| Ukuchongwa | NMR | Iyahambelana |
| PH | 2.5~3.5 | 3.3 |
| Ilahleko ekomisweni | 1.0% Ubuninzi | 0.041% |
| Amanzi | 1.0% Ubuninzi | 0.052% |
| 5'-CMP | NMT1.0% | 0.10% |
| Ulawulo lweMichiza | ||
| Iintsimbi ezinzima | NMT10PPM | Iyahambelana |
| IArsenic(As2O3) | NMT1PPM | Iyahambelana |
| Isulfate(SO4) | NMT 0.020% | Iyahambelana |
| Intsimbi(Fe) | NMT10PPM | Iyahambelana |
| Ikloridi(Cl) | NMT 0.020% | Iyahambelana |
| Intsalela yokunyibilikisa | Ukudibana nomgangatho we-EU/USP | Iyahambelana |
| Ulawulo lweMicrobiological | ||
| Ukubalwa kwePleti iyonke | 10,00cfu/g Ubuninzi | Iyahambelana |
| Igwele kunye noMngundo | 100cfu/g Ubuninzi | Iyahambelana |
| E.Coli | Ibi/10g | Iyahambelana |
| Salmonella sp. | Ibi/25g | Iyahambelana |
| Staph Aureus | Ibi/10g | Iyahambelana |
| Pseudomonas aeruginosa | Ibi/25g | Iyahambelana |
| Ukupakisha kunye noGcino | ||
| Ukupakisha | Pakisha kwi-paper-drums.25Kg/Drum 1Kg kwingxowa yeplastiki nganye | |
| Ugcino | Gcina kwisitya esivalwe kakuhle kude nokufuma kunye nelanga elithe ngqo. | |
| Beka ubomi kwishelufa | Iminyaka emi-2 ukuba itywinwe kwaye igcinwe ngokufanelekileyo. | |
| Ulwazi oluninzi lweTRB | ||
| Risiqinisekiso somthetho | ||
| USFDA,CEP,KOSHER HALAL GMP ISO Certificates | ||
| Umgangatho othembekileyo | ||
| Phantse iminyaka engama-20, ukuthumela ngaphandle kumazwe angama-40 kunye nemimandla, ngaphezulu kwe-2000 iibhetshi eziveliswe yi-TRB ayinazo naziphi na iingxaki zomgangatho, inkqubo yokucoca ekhethekileyo, ukungcola kunye nolawulo lococeko ludibana ne-USP, EP kunye neCP | ||
| Inkqubo yoMgangatho eBanzi | ||
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| ▲ Inkqubo yoQinisekiso lobulunga | √ |
| ▲ Ulawulo lwamaxwebhu | √ | |
| ▲ Inkqubo yoQinisekiso | √ | |
| ▲ Inkqubo yoQeqesho | √ | |
| ▲ iProtokholi yoPhicotho lwaNgaphakathi | √ | |
| ▲ Inkqubo yoPhicotho lweNtengiso | √ | |
| ▲ Inkqubo yeZixhobo zeZixhobo | √ | |
| ▲ Inkqubo yoLawulo lweMathiriyeli | √ | |
| ▲ Inkqubo yoLawulo lweMveliso | √ | |
| ▲ Inkqubo yokuPakisha ukuLayibhela | √ | |
| ▲ Inkqubo yoLawulo lweLabhoratri | √ | |
| ▲ Inkqubo yoQinisekiso loQinisekiso | √ | |
| ▲ Inkqubo yeMicimbi yoLawulo | √ | |
| Lawula Imithombo Epheleleyo kunye Neenkqubo | ||
| Ukulawulwa ngokungqongqo yonke imathiriyeli ekrwada, izincedisi kunye nokupakishwa kwemathiriyeli. Imathiriyeli ekrwada ekhethwayo kunye nezincedisi kunye nomthengisi wemathiriyeli yokupakisha enenombolo yase-US ye-DMF. Ababoneleli abaninzi bezinto ezikrwada njengesiqinisekiso sobonelelo. | ||
| AMaziko eNtsebenziswano awomeleleyo ukuxhasa | ||
| Iziko lebhotani/Iziko leMicrobiology/Iziko leSayensi neTekhnoloji/Dyunivesithi | ||
