Igama lemveliso:I-Spermidine Trihydrochloride

Elinye Igama:1,4-Butanediamine,N1-(3-aminopropyl)-, hydrochloride (1:3);I-Spermidine hydrochloride; I-Spermidinetrihydrochloride

Inombolo yeCAS:334-50-9

IsiVavanyo: 98.0%Mis

Umbala: Umgubo omhlophe

Ukupakisha: 25kgs / igubu

I-Spermidine trihydrochloride yikhompawundi ye-polyamine efumaneka ngokubanzi kwiiseli zomntu kunye nemithombo eyahlukeneyo yokutya. Idlala indima ebalulekileyo ekusebenzeni kweeseli kwaye iyaziwa ngokuba nenxaxheba kwiinkqubo ezifana ne-DNA synthesis, iprotein synthesis, kunye nokukhula kweeseli.

I-Spermidine yinto eyenzeka ngokwemvelo yepolyamine efumaneka phantse kuzo zonke iiseli eziphilayo. Idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zeselula, ezinjengokugcina uzinzo lwe-DNA, ukukhuphela i-DNA kwi-RNA, kunye nokuthintela ukufa kweeseli. Phakathi kwabo, i-spermidine trihydrochloride powder luhlobo lwe-spermidine oluye lwacutshungulwa lwaba ngumgubo ukuze lusetyenziswe lula. Ngokufanayo, i-spermidine trihydrochloride nayo inefuthe lokulibazisa ukuguga. Ngenxa yamandla ayo okukhuthaza i-autophagy, inkqubo yendalo emzimbeni enceda ukucacisa iiseli ezonakalisiweyo kunye namacandelo eselula. I-Autophagy ibalulekile ekugcineni impilo yeeseli kunye nokuthintela ukuqokelelwa kwezinto ezinobuthi emzimbeni. Ngokukhuthaza i-autophagy, i-spermidine trihydrochloride inokunceda ukuxhasa impilo kunye nomsebenzi weselula. Ukongeza kwindima yayo ekukhuthazeni i-autophagy, i-spermidine trihydrochloride ifundwe ngeziphumo zayo zokuchasana nokuguga. Ngokubanzi, i-Spermidine Trihydrochloride Spermine Powder yikhompawundi ekwazi ukukhuthaza impilo yeseli, ukuxhasa umsebenzi we-cardiovascular, kunye nokunciphisa inkqubo yokuguga. I-Spermidine trihydrochloride, ngakolunye uhlangothi, yindlela yetyuwa ye-spermidine kwaye isetyenziswa ngokuqhelekileyo kuphando lwesayensi kunye nezicwangciso zebhubhoratri. Ukongeza ityuwa ye-hydrochloride kwi-spermidine yenza i-spermidine trihydrochloride, ezinzileyo kwaye i-soluble ngakumbi emanzini kune-spermidine yodwa. Oku kwenza kube lula ukuphatha kunye nokulawula kwiseto zovavanyo.

I-Spermidine i-polyamine.Isasazwa ngokubanzi kwizinto eziphilayo, ihlanganiswe yi-biosynthesis ye-puthumine (i-butylenediamine) kunye ne-adenosine methionine.I-Neuronal NO synthase (nNOS) inokuvinjelwa.Ibophelela kunye ne-precipitates DNA;
Ingasetyenziselwa ukuhlambulula iiproteni ezibophelelayo kwi-DNA. Ukongezelela, i-spermidine ivuselela umsebenzi we-T4 polynucleotide kinase. Ibandakanyeka ekukhuleni, ekuphuhliseni, nasekuphenduleni uxinzelelo kwizityalo.
I-Spermidine Trihydrochloride yi-NOS1 inhibitor kunye ne-NMDA kunye ne-T4 activator. I-Spermidine Trihydrochloride yayikwisifundo sokwakheka kunye nokusebenza kweepolyamines, apho i-potassium kunye ne-sodium ion zafunyanwa ukukhuthaza iziphumo ezahlukeneyo xa zibophelela nge-polyamines.

Umsebenzi:

I-Spermidine yincindi yentsholongwane yengqolowa, ekhutshwe kwi-Triticum aestivum L. I-Spermidine, yokuqala yodwa kwi-semen okanye kwi-sperm, isithako se-polyamine esinyibilikayo emanzini esenzeka ngokwemvelo kuzo zonke izihlunu zemizimba yethu yabantu kwaye ikwafumaneka nakwezinye izinto ezininzi ezifana nezilwanyana. , izityalo, kunye nokutya okuqhelekileyo kokutya. I-Spermidine iyakwazi ukungena kwi-membrane ye-biological kwaye ikholelwa ukuba iluncedo ekuhlaziyweni kweeseli kunye neenjongo zokulwa nokuguga ....I-Spermidine Trihydrochloride yi-NOS1 inhibitor kunye ne-NMDA kunye ne-T4 activator. I-Spermidine Trihydrochloride yayikwisifundo sokwakheka kunye nokusebenza kweepolyamines, apho i-potassium kunye ne-sodium ion zafunyanwa ukukhuthaza iziphumo ezahlukeneyo xa zibophelela nge-polyamines.
Ikwasetyenziselwa ukuhlambulula iiprotheyini ezibophezelayo ze-DNA.I-T4 i-polynucleotide kinase umsebenzi iyakhuthazwa.Ukuguga kweprotheyini.

1. Ispermine inokuthintela ukuwohloka kwenkumbulo enxulumene nobudala.
2. I-Spermine inokulibazisa ukuqala kwe-dementia.
3. I-Spermine inokulibazisa i-senescence ukukhuthaza ukuthotywa kweprotheni synthesis okanye ukumisa.
Isicelo:

Nangona i-spermidine ivela ngokwemvelo kwiintlobo ezahlukeneyo zokutya, amanqanaba ayo ahluka kakhulu. Ukutya okutyebileyo kwi-spermidine kubandakanya iintlobo ezithile zetshizi (ezifana netshizi endala), amakhowa, iinkozo, iimbotyi kunye neemveliso zesoya, ezifana ne-tempeh. Nangona kunjalo, ukufumana amanqanaba aneleyo e-spermidine ngokutya kuphela kunokuba ngumngeni. Ngoko ke, izongezo zokutya eziqulethe i-spermidine trihydrochloride zithandwa njengendlela efanelekileyo yokuqinisekisa ukuba i-intake.Le khompawundi isetyenziswa ngokuyintloko kwizongezo zokutya, kwaye izibonelelo zayo zifikeleleke kakhulu, ukusuka kwimiphumo yokuchasana nokuguga ukukhuthaza impilo yentliziyo kunye nengqondo, ukwandisa ukugonywa. , ukuthintela ukulahleka kwemisipha, kunye nokondla iinwele kunye nolusu. I-Spermidine i-polyamine.Isasazwa ngokubanzi kwizinto eziphilayo, ihlanganiswe yi-biosynthesis ye-puthumine (i-butylenediamine) kunye ne-adenosine methionine.I-Neuronal NO synthase (nNOS) inokuvinjelwa.Ibophelela kunye ne-precipitates DNA;

Ingasetyenziselwa ukuhlambulula iiproteni ezibophelelayo kwi-DNA. Ukongezelela, i-spermidine ivuselela umsebenzi we-T4 polynucleotide kinase. Ibandakanyeka ekukhuleni, ekuphuhliseni, nasekuphenduleni uxinzelelo kwizityalo.