Igama Lomkhiqizo:I-Spermidine Trihydrochloride

Elinye Igama:1,4-Butanediamine,N1-(3-aminopropyl)-, i-hydrochloride (1:3);I-Spermidine hydrochloride; I-Spermidinetrihydrochloride

Inombolo ye-CAS:334-50-9

Isivivinyo: 98.0%Miniz

Umbala: Impushana emhlophe

Ukupakisha: 25kgs / isigubhu

I-Spermidine trihydrochloride iyinhlanganisela ye-polyamine etholakala kakhulu kumaseli womuntu kanye nemithombo yokudla ehlukahlukene. Idlala indima ebalulekile ekusebenzeni kwamangqamuzana futhi yaziwa ngokubandakanyeka ezinqubweni ezifana nokuhlanganiswa kwe-DNA, ukuhlanganiswa kwamaprotheni, nokukhula kwamaseli.

I-Spermidine iyinhlanganisela ye-polyamine eyenzeka ngokwemvelo etholakala cishe kuwo wonke amaseli aphilayo. Idlala indima ebalulekile ezinqubweni ezihlukahlukene zamangqamuzana, njengokugcina ukuqina kwe-DNA, ukukopisha i-DNA ku-RNA, nokuvimbela ukufa kwamangqamuzana. Phakathi kwazo, i-spermidine trihydrochloride powder iwuhlobo lwe-spermidine oluye lwacutshungulwa lwaba yimpushana ukuze lusetshenziswe kalula. Ngokufanayo, i-spermidine trihydrochloride nayo inomphumela wokubambezela ukuguga. Ngenxa yamandla ayo okukhuthaza i-autophagy, inqubo yemvelo emzimbeni esiza ukusula amaseli awonakele kanye nezingxenye zamaselula. I-Autophagy ibalulekile ekugcineni impilo yamaseli nokuvimbela ukunqwabelana kwezinto ezinobuthi emzimbeni. Ngokuphromotha i-autophagy, i-spermidine trihydrochloride ingasiza ukusekela impilo nokusebenza kwamaselula jikelele. Ngaphezu kwendima yayo ekukhuthazeni i-autophagy, i-spermidine trihydrochloride iye yafundelwa imiphumela yayo engaba khona yokulwa nokuguga. Sekukonke, i-Spermidine Trihydrochloride Spermine Powder iyinhlanganisela enamandla okukhuthaza impilo yamangqamuzana, ukusekela umsebenzi wenhliziyo nemithambo yegazi, futhi engase ibambezele inqubo yokuguga. I-Spermidine trihydrochloride, ngakolunye uhlangothi, uhlobo lukasawoti lwe-spermidine futhi luvame ukusetshenziswa ocwaningweni lwesayensi nasezilungiselelweni zaselabhorethri. Ukwengeza usawoti we-hydrochloride ku-spermidine kwakha i-spermidine trihydrochloride, ezinzile futhi encibilika kakhulu emanzini kune-spermidine iyodwa. Lokhu kwenza kube lula ukuphatha nokuphatha kuzilungiselelo zokuhlola.

I-Spermidine iyi-polyamine.Isatshalaliswa kakhulu ezintweni eziphilayo, ihlanganiswa yi-biosynthesis ye-puthumine (butylenediamine) kanye ne-adenosine methionine.I-Neuronal NO synthase (nNOS) ingavinjelwa.Ibopha futhi ikhiphe i-DNA;
Ingase isetshenziselwe ukuhlanza amaprotheni abopha i-DNA. Ukwengeza, i-spermidine ivuselela umsebenzi we-T4 polynucleotide kinase. Kuhileleke ekukhuleni, ekuthuthukisweni nasekuphenduleni ukucindezeleka ezitshalweni.
I-Spermidine Trihydrochloride iyi-NOS1 inhibitor kanye ne-NMDA kanye ne-T4 activator. I-Spermidine Trihydrochloride yayisocwaningweni lwesakhiwo nokusebenza kwama-polyamines, lapho kutholakala khona i-potassium ne-sodium ion ukukhuthaza imiphumela ehlukene lapho kubopha nge-polyamines.

Umsebenzi:

I-Spermidine iwuketshezi kakolweni, ekhishwe ku-Triticum aestivum L. Spermidine, eyaqala ukuhlukaniswa nesidoda noma isidoda, iyisithako se-polyamine esincibilika emanzini esenzeka ngokwemvelo kuzo zonke izicubu zemizimba yethu yabantu futhi sitholakala nakwezinye izinto eziningi eziphilayo njengezilwane. , izitshalo, kanye nokudla okuvamile okudliwayo. I-Spermidine iyakwazi ukungena kulwelwesi lwebhayoloji futhi kukholakala ukuthi inenzuzo ekuvuseleleni amaseli nezinjongo zokulwa nokuguga….I-Spermidine Trihydrochloride iyi-NOS1 inhibitor kanye ne-NMDA ne-T4 activator. I-Spermidine Trihydrochloride yayisocwaningweni lwesakhiwo nokusebenza kwama-polyamines, lapho kutholakala khona i-potassium ne-sodium ion ukukhuthaza imiphumela ehlukene lapho kubopha nge-polyamines.
Iphinde isetshenziselwe ukuhlanza amaprotheni abophezelayo e-DNA.Umsebenzi we-T4 polynucleotide kinase uyakhuthazwa.Ukuguga kwamaprotheni okubambezelekile.

1. I-Spermine ingavimbela ukwehla kwenkumbulo ehlobene neminyaka.
2. I-spermine ingabambezela ukuqala kokuwohloka komqondo.
3. I-Spermine ingabambezela i-senescence ukukhuthaza ukuwohloka kwe-protein synthesis noma ukuwamisa.
Isicelo:

Nakuba i-spermidine yenzeka ngokwemvelo ekudleni okuhlukahlukene, amazinga ayo ahluka kakhulu. Ukudla okunothe nge-spermidine kufaka phakathi izinhlobo ezithile zikashizi (njengoshizi osekhulile), amakhowe, okusanhlamvu, ubhontshisi nemikhiqizo yesoya, njenge-tempeh. Kodwa-ke, ukuthola amazinga e-spermidine anele ngokudla kuphela kungaba yinselele. Ngakho-ke, izithasiselo zokudla eziqukethe i-spermidine trihydrochloride zithandwa njengendlela elula yokuqinisekisa ukungenisa okufanelekile.Le nhlanganisela isetshenziselwa ikakhulukazi izithasiselo zokudla, futhi izinzuzo zayo zifinyelela kude, kusukela emiphumeleni yokulwa nokuguga ekukhuthazeni impilo yenhliziyo nengqondo, ukuqinisa ukuzivikela komzimba. , ukuvimbela ukulahleka kwemisipha, nokuqinisa izinwele nesikhumba. I-Spermidine iyi-polyamine.Isatshalaliswa kakhulu ezintweni eziphilayo, ihlanganiswa yi-biosynthesis ye-puthumine (butylenediamine) kanye ne-adenosine methionine.I-Neuronal NO synthase (nNOS) ingavinjelwa.Ibopha futhi ikhiphe i-DNA;

Ingase isetshenziselwe ukuhlanza amaprotheni abopha i-DNA. Ukwengeza, i-spermidine ivuselela umsebenzi we-T4 polynucleotide kinase. Kuhileleke ekukhuleni, ekuthuthukisweni nasekuphenduleni ukucindezeleka ezitshalweni.