Igama lomkhiqizo: 5a-HydroxyLaxogenin

Elinye Igama: 5A-hydroxy lacosgenin

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I-Laxogenin, eyaziwa nangokuthi i-5 α Hydroxy Laxogenin noma i-5a hydroxy Laxogenin ibizwa ngokuthi i-plant steroid ngoba isuka ku-Smilax Sieboldii, equkethe i-brassinosteroids.

5a-Hydroxy Laxogenin, eyaziwa nangokuthi i-Laxogenin, iyinhlanganisela yezitshalo etholakala ku-rhizome ye-Smilax Sieboldii, isitshalo esidabuka e-Asia. Kungokweqembu lezinhlanganisela ezibizwa nge-brassinosteroids, ezaziwa ngamandla azo okusekela ukukhula kwemisipha, amandla, nokululama. Ngokungafani ne-anabolic steroids, i-5a-Hydroxy laxogenin ibhekwa njengenye indlela yemvelo.

I-5a-Hydroxy Laxogenin iyi-sapogenin, ekhishwe ezitshalweni ezifana ne-asparagus, le nhlanganisela iyinhlanganisela ye-spirochete efana ne-brassinosteroids, inani elincane lemikhiqizo yezitshalo etholakala ezitshalweni nokudla okufana nempova, imbewu, namaqabunga. Ngo-1963, izinzuzo ze-anabolic ze-laxogenin zacwaningwa ngethemba lokuyithengisa njengesithasiselo sokwakha imisipha. I-5a-Hydroxy laxogenin ikhuthaza ukuhlanganiswa kwamaprotheni, inqubo ebalulekile yokwakha nokulungisa imisipha. Ngokwandisa ukwakheka kwamaprotheni omzimba, le nhlanganisela ingakwazi ukusekela ukukhula nokululama kwemisipha, okuvumela abantu ukuthi bafinyelele imigomo yabo yokufaneleka ngempumelelo kakhudlwana. Ukwengeza, i-5a-Hydroxy laxogenin kucatshangwa ukuthi isiza ukunciphisa ukulimala kwemisipha nokuvuvukala, ngaleyo ndlela isize ukululama ngokushesha futhi ithuthukise ukusebenza okuphelele. Ukwengeza, ucwaningo lubonisa ukuthi le nhlanganisela ingaba nomthelela omuhle enzuzweni yamandla, iyenze ibe isengezo esibalulekile ekuqeqesheni amandla kanye nezinhlelo zokuzivocavoca umzimba.

I-Laxogenin (3beta-hydroxy-25D,5alpha-spirostan-6-one) iyinhlanganisela ethengiswa ngezindlela ezihlukahlukene njengesengezo se-muscle-toning. Ingokwesigaba samahomoni ezitshalo abizwa nge-brassinosteroids, anesakhiwo esifanayo namahomoni e-steroid ezilwane. Ezitshalweni, zisebenza ukukhulisa ukukhula.
Iziqu ezingaphansi komhlaba zesitshalo sase-Asia i-Smilax sieboldii ziqukethe cishe u-0.06% we-laxogenin futhi ziwumthombo wayo wemvelo oyinhloko. I-Laxogenin iphinde itholakale ku-anyanisi waseShayina (i-Allium chinense) ama-bulb.
I-Laxogenin ezithasiselweni ikhiqizwa esitshalweni esivame kakhulu i-steroid, i-diosgenin. Eqinisweni, i-diosgenin isetshenziswa njengempahla eluhlaza engaphezu kuka-50% we-synthetic steroids kuhlanganise ne-progesterone.

Imisebenzi:
(1) I-Laxogenin isiza ukwandisa ukwakheka kwamaprotheni ngaphezu kuka-200% okuvumela umsebenzisi ukusheshisa ukukhula kwemisipha nokululama.
(2) Inikeza ukwesekwa kwe-cortisol, ngaleyo ndlela ivumele umzimba wakho ukuba ululame ngokushesha futhi inciphise ukuwohloka kwemisipha (ukumoshakala kwemisipha).
(3) Abasubathi bathi babone amandla enyuka ezinsukwini ezingu-3-5, futhi isisindo semisipha sikhuphuka emavikini angu-3-4.
(4) Ayiguquli abasebenzisi ibhalansi yemvelo ye-hormonal(ayithinti amazinga e-testosterone futhi ayiguquli ibe i-estrogen noma ibangele i-estrogen yemvelo yomzimba ukuba yande).

Izicelo:

I-5a-Hydroxy laxogenin iyinhlanganisela ye-homologous ye-lasogenin, i-steroid yemvelo etholakala ezitshalweni eziningi eziluhlaza. Inomsebenzi we-anabolic/androgenic futhi ifana kakhulu ne-anabolic enamandla kakhulu, i-anavar. Kuyinhlanganisela ye-anabolic kakhulu ekhuthaza ukukhula kwemisipha ethambile emzimbeni. Kuyinhlanganisela ethengiswa ngezindlela eziningi njengezithako ze-muscle-toning. Ingasiza ukusheshisa ukukhula kwemisipha ethambile. Yandisa ukwakheka kwamaprotheni futhi iqinisekisa ukuthi umzimba wakho awephuli amaprotheni emisipha. Ngamaprotheni emisipha engeziwe, umzimba wakho uzokwazi ukuthuthukisa ngokuphawulekayo ukusebenza kwawo, futhi ungaphula amangqamuzana amafutha.Nakuba ucwaningo oluncane kakhulu lwenziwe ukuze kutholakale imiphumela egcwele ye-Laxogenin, idatha eminingi ehlanganiswe kwamanye ama-AAS iye yahlanganiswa. isetshenziswa njenge-proxy ye-Laxogenin. Eminye yemiphumela evela ocwaningweni olumbalwa olwenziwe ku-Laxogenin ihlanganisa;I-Laxogenin ingasebenza esikhundleni esisebenzayo sama-prohormone. Kungabhekwa njengohlobo lokwakhiwa kwemisipha. Uma ukhetha umuthi ohlukile kumazinga we-hormone enomthelela njengama-prohormones, nama-blocker e-estrogen. I-Laxogenin isiza abasebenzisi ukuthi bathuthukise ukusebenza futhi balulame ngokushesha.
1.I-Laxogenin isetshenziselwa Ukwelapha Nge-Post Cycle Therapy.
2.I-Laxogenin ibangela ukwenyuka kokululama ekukhathaleni kwengqondo noma ekukhathaleni. Ibhekana nengcindezi futhi isize imizwa izole kalula.
3.Laxogenin inikeza ukululama ngokushesha ekuguleni, ezifweni nasezinhlungwini. Uma isetshenziswa ngama-antibiotics, i-Laxogenin izosheshisa umsebenzi we-4.izidakamizwa ukuphulukisa amanxeba nezilonda ngokushesha okukhulu.
5.I-Laxogenin isiza ukusebenza kwamaprotheni, uma idliwe. Esimeni lapho ungathandi izithasiselo ezisuselwe kumaprotheni noma ukuwohloka kwamaprotheni 6.imikhiqizo efana nama-BCAA. I-Laxogenin ingasetshenziswa kanye nezinye izithako ezifana ne-creatine ne-epicatechin.
Kukusiza ukwakha imisipha, amandla namandla ngokushesha okukhulu. Lokhu kuhle ikakhulukazi kubantu abenza izivivinyo zomzimba.