Igama lomkhiqizo:I-celery leaf extractApigenin 98%
Igama lesiLatini: APIEM Gromololens L.
I-CO CHA: 520-36-5
Ingxenye yesitshalo esetshenzisiwe: iqabunga
Isithako:Apigen
Assay:ApigenI-98.0% yi-HPLC
Umbala: nsundu ku-powder ophuzi ngephunga elicacile nokunambitha
Isimo se-GMO: GMO Mahhala
Ukupakisha: Ku-25kgs fiber izigubhu
Isitoreji: Gcina isitsha esingenakuphikwa ngendawo epholile, eyomile, gcina kude nokukhanya okuqinile
Impilo yeshelufu: izinyanga ezingama-24 kusukela ngosuku lokukhiqizwa
Imbewu ye-celery ekhipha i-apigenin engu-98%: Isengezo semvelo se-premium sempilo ephelele
Ukubuka konke komkhiqizo
Imbewu ye-celery ekhipha i-apigenin engu-98%yisithako semvelo esiphakeme esivela kwimbewu yeAmathuna we-apium, ihlelwe ukuletha ama-apiigenin angama-98% - adume nge-biononic edume ngezinzuzo zawo zezempilo ezibumbene. Lokhu kukhishwa kukhiqizwa ukukhishwa okuthuthukile kwe-ethanol-emanzini kanye nezinqubo ezilawulwa yikhwalithi, ukuqinisekisa ukusebenza kahle nokuphepha. Ilungele ukudla okunempilo okunempilo, okusebenzayo, kanye nezicelo zemithi, kuhlanganisa ukuhlakanipha kwe-Herbate yendabuko ngokuqinisekiswa kwesayensi kwanamuhla.
Izinzuzo zezempilo ezibalulekile
- Ukwesekwa kwenhliziyo
- Yehlisa umfutho wegazi & ne-cholesterol: Kuqukethe ama-phthalides (isib.
- Imiphumela ye-Anti-Hyptivensivence: Kuboniswe ekuvivinyweni kwemitholampilo ukuthuthukisa i-vasodilation kanye nokuhamba nge-calcium / potassium flow kumaseli we-vascular, kunciphisa ubungozi we-hypertension.
- I-Anti-inflammatory & Antioxidant Properties
- Ukulwa nokuvuvukala okungamahlalakhona okuxhumene nesifo samathambo, ukuphazamiseka kwesibindi, kanye nezifo zenhliziyo ngama-flavonoroids (apigenin, quercetin) nama-polysaccharides.
- Ama-radicals wamahhala anama-acidi e-phenolic acid (i-caffeic acid, e-ferulic acid), evikela ukucindezelwa okuxakile kanye nomonakalo wamaselula.
- Hepatorprotticty & yokugaya insiza
- Yehlisa ukunqwabelana kwamafutha wesibindi, kuthuthukisa umsebenzi we-enzyme, futhi kukhuthaza ukuguqulwa kwe-detoxation ngokuthuthukisa ukuhamba kwe-bile.
- Izenzo njenge-diuretic, inenselela ukuqhakaza, futhi isekela impilo ye-gut ngokulinganisa ama-gastric mucus kanye nokunciphisa ukwakheka kwesilonda.
- Ukuvimbela umdlavuza nokuxhaswa komzimba
- I-Apigenin ivimbela ukukhula kwemisila ngokuguqula umsebenzi we-hormone, ukuvimba ukwanda kwamaseli we-mutagenic, nokuvikela ubuqotho be-DNA.
- Ama-polyacetysenes nama-antimicrobial compounds alwa nezifo ezingama-bacterial (isib.
- I-Metabolic ne-Qunititive Encyment
- Iqinisa umsebenzi we-mitochondrial, ukuphathwa kwesisindo se-AIDS, futhi kuthuthukisa ukusebenza kokusebenza ngokwandisa i-lipid metabolism.
- Isekela i-Neuroprotection ne-Qunititive Health ngeqhaza likaPipin ku-Neurogeneis elivuselelayo kanye nokunciphisa i-neuroinflammation.
Izinja
- Ama-NutriCeuticals: ahlelwe kuma-caplule (500-1500 mg / ngosuku) ngempilo yenhliziyo, anti-ukuguga, nokuxhaswa komzimba.
- Ukudla okusebenzayo: Kungezwe kubaphuza iziphuzo, imigoqo yamaprotheni, kanye nokudla okulula kwezinzuzo ze-metabolic ne-antioxidant.
- Izemithi: Isetshenziswa ekwakhekeni kwe-antihypensive, izidakamizwa ze-hepatorprotute, kanye nama-anti-cancer adgevants.
- I-COSMECEETICALS: Ifakwe eSkincare yemiphumela yokulwa nokuvuvukala kanye nokuvumelanisa.
- Umenzeli we-Flavoting: Khulisa amaphrofayli asindwayo kumasobho, amasoso, nemikhiqizo yenyama njengenye indlela yemvelo yokungezelelwa kwezitha.
Ukucaciswa kobuchwepheshe
- Isithako esisebenzayo: Apigenin ≥98% (HPLC).
- Indlela yokukhishwa: I-Solvent ye-Ethanol-Water, eyomile ngeMaltodilextrin.
- Ukubukeka: Okumhlophe okuhle ku-off powder emhlophe.
- Izitifiketi: Okungeyona-i-GMO, i-Gluten-free, azikho izithasiselo.
Kungani Sikhethe US?
- Ukwenza ngokwezifiso: Kutholakala ku-powder ngobuningi, amaphilisi, noma okukhishwe uketshezi lokulebula kwangasese.
- Ukulethwa okusheshayo: Kuthunyelwe nge-DHL / FedEx (izinsuku ezingama-5-10) noma izimpahla zasolwandle (izinsuku eziyi-15-45).
- Ukuqinisekiswa kwekhwalithi: Ilungelo lesithathu lihlolwe ubumsulwa, i-potency, kanye nezinsimbi ezisindayo.
- Amasampula wamahhala: Amasampula we-5-10 g ahlinzekelwe ukuqinisekiswa kwelebhu.
Ukuphepha nokusetshenziswa
- Umthamo: 500-1500 mg nsuku zonke, kulungiswe ngokwenza okuthile.
- Ukuqapha: Kungathintana nezidakamizwa zeCyp3a4-Metabolized (isib., Ama-statics, ama-anticoagulants). Thintana nomhlinzeki wezempilo uma ukhulelwe noma emithini
Umphumela We-Anti-TheMunye
I-Apigenin idlala indima ebalulekile ekuvimbeleni umdlavuza ngokufaka i-apoptosis emigqeni ehlukahlukene yeseli.
Umdlavuza we-Ovarian:
Olunye ucwaningo lwathola ukuthi i-Apigenin ingavimba ukukhula, ukwanda, kanye nokudluliselwa kwe-CA-OV3 (Iseli Lomdlavuza Wabantu Loman); Ifaka i-apoptosis ye-CA-OV3 ngokugcina ama-cell cell cell stasis ku-G2 / M M Phase. Umphumela uhlobene nesikhathi nesikhathi.
Umdlavuza we-pancreatic:
I-Apigenin ingavimbela ukwanda kwamaseli womdlavuza we-pancreatic. I-Apigenin ibulala isimila ngokunciphisa umthombo we-glucose, okungukudla okuhlala kuwo amakhansela amangqamuzana. Ngaphandle kwalokho, i-apiigenin ingathuthukisa ukusebenza kahle kwezidakamizwa ze-chemotherapy.
I-Chemo-Sensitization
Kutholakale ukuthi i-apigenin kokuqukethwe okuphansi yayinomphumela ophansi we-cytotoxic futhi ayikwazanga ukuheha amaseli we-leukemia we-leukemia (HL-60) ane-apoptosis ngempumelelo. Kodwa-ke, i-apiigenin ingathuthukisa umphumela wokuvinjwa kwe-CISPLATIn (DDP) kwi-HL-60 cell Proliferation ngenkathi ihlanganisa nokugxila okuhlukile kwe-DDP. Ngakho-ke i-apiigenin ingahle ibe nomphumela wokuzwela kwe-chemotherapy ku-HL-60; Ukugxila okuphansi kwe-apiigenin kunganciphisa futhi ukumelana kwamaseli we-HL-60 kuye kuma-apoptosis aqoqwe nge-chemotherapy, okungahle kuhlobane nokulawulwa phansi kwe-NF-REB ne-BCL-2. (NF-KB uhlobo lweprotheni elawula ukuphrinta kwe-DNA, ukukhiqizwa kwama-cytokines kanye nokusinda kwamaseli;
Ukuvikelwa kwesibindi
I-Apiigenin inganciphisa ukulimala kwesibindi okuphoqelelwa yi-Ischemia-RepperFusion ngokusebenzisa ukwengenisa i-perconidation ye-lipid futhi ihlehlise ama-radicals wamahhala.
I-Apiigenin inganciphisa ukulimala kwesibindi okubangelwa ukucindezelwa kwe-oxidative ngenxa yemisebenzi yayo enamandla ye-antioxidant kanye ne-anti-inflammatory.
Ukuhlolwa kokhemisi kuveze ukuthi i-apiigenin inomphumela wokuvikela obonakalayo wokulimala kwesibindi / i-hepatocyte, kanti inqubo yayo eyinhloko ihlobene nokuvinjwa kwe-CYP2E1 evezwa ngesibindi / hepatocyte.
Vikela i-osteoporosis
I-Apigenin ivimbela i-osteoblastogenesis, i-osteoclastogenesis, futhi ivimbela ukulahleka kwamathambo.
I-Apigenin ivikela izicubu zamathambo ngokunciphisa ukulahleka kwamathambo emzimbeni.
Ezinye izifundo ezihlobene ne-MC3T3-E1, i-Osteoblast Predursor Cell Ulayini osususelwa kuMus MusCulus (Mouse), uthole ukuthi i-apigenin ingavimba imfihlo yama-cytokines ambalwa akhuthaza ukwakheka kwama-osteoclast.
I-Apigenin iphinde yavimbela umehluko wamaseli we-3T3-L1 adipose amaseli e-adipocyte anamandla amakhulu, ngakho-ke kuvimbela ukuhlukaniswa kwe-Adipocyte Eviving Adipocyte ehlukile
I-Apigenin ivimbela umehluko wama-osteoclasts kusuka kuma-RAW264.7 amaseli weseli bese uvimbela ukwakheka kwama-osteoclasts ahlaselwe yi-multinucleated. Kungafaka futhi i-osteoclast apoptosis futhi uvimbele ukuqubuka kwethambo.
Umsebenzi wokulwa nokuvuvukala kanye nokulwa ne-oxidant
I-Apiigenin ivimbela inqubo yokuvuvukala, yandisa amazinga we-IL-10 futhi isebenzisa amapharamitha we-oxidative stress
I-Apigenin inatibits Coughbatory Cytokines futhi ikhuthaza ukukhiqizwa kwe-cytokine okulwa nokuvuvukala.
Ezinye izincwadi zibonisa ukuthi i-apiigenin idela izicubu zokuvuvukala kwezicubu ezibangelwa ukucindezelwa oxpidative ezicutshini ngokushintsha amamaki ahlukahlukene okucindezela oxidative, i-Interleukins, amamaki we-enzyme ahlobene namanye ama-enzyme.
Umthethonqubo we-Endocrine
I-Apiigenin ingalawula ushukela wegazi, phatha ukuncipha kwe-thyroid kanye nokulawula i-lipid peroxidation.it yatholakala ukuthi i-apigenin ingakhuphula amazinga e-insulin kanye ne-thyroxine ezilwaneni zikashukela, futhi anciphise ukugcwala kukashukela wegazi kanye nomsebenzi we-glucose-6-PASE).
I-Apigenin yaguqula imiphumela ye-cholesterol ekhuphukayo ye-serum, i-LPOL ye-Lipid Peroxidation (LPO) kanye nemisebenzi eyehlisiwe yama-antioxidants antioxidants antioxidate (cat) kanye ne-superoxide dismutase (sod) kanye nezilwane ezibangelwa yi-alloxan.
Ezilwaneni ezinoshukela wegazi ojwayelekile, i-apiigenin nayo inganciphisa i-serum cholesterol kanye nesibindi le-lipid petoxidation, futhi yandise umsebenzi wama-antioxidants kumaseli.
Izakhiwo zekhemisi ze-apigenin
I-Apigenin ifakwe ngokubaluleka okukhulu eminyakeni yamuva nje, njengomgqugquzeli wezempilo onenzuzo ngenxa yobuthi bayo obuphansi obuphansi nemiphumela yayo yezempilo kuma-flavonoids ahlobene nomdlavuza ajwayelekile, aqhathaniswa namanye ama-flavonoid ahlobene nesakhiwo. Kunobufakazi bocwaningo obukhombisile ukuthi i-apigenin inamandla amakhulu okulapha izifo eziningi
