dawb peony extract

Khoom npe:Dawb Peony Extracthmoov

Lwm Lub Npe:Suav Dawb Blossom Extract Powder

Botanical Source:Radix Paeoniae Alba

Cov khoom xyaw:Tag nrho cov glucosides ntawm Paeonia (TGP):Paeoniflorin, Oxypaeoniflorin, Albiflorin, Benzoylpaeoniflorin

Specifications:Paeoniflorin10% ~ 40% (HPLC), 1.5%Albasides, 80%Glycosides

CAS Nr:.23180-57-6

Xim: Yellowish-xim avhmoovnrog cov yam ntxwv tsw thiab saj

GMOStatus: GMO Dawb

Ntim: hauv 25kgs fiber ntau nruas

Cia: Khaws lub thawv tsis qhib hauv qhov chaw txias, qhuav, Khaws kom deb ntawm lub teeb muaj zog

Lub neej txee: 24 lub hlis txij li hnub tsim khoom

Dawb Peony Extracthais txog kev rho tawm cov khoom xyaw nquag los ntawm cov peony dawb los ntawm kev tshawb fawb los ntawm kev siv tshuab tshwj xeeb.Raws li kev soj ntsuam ntawm cov kws tshawb fawb, cov khoom xyaw nquag ntawm peony extract rau tib neeg lub cev yog raws li hauv qab no Daim Ntawv Qhia.Plaub qhov tseem ceeb tshaj plaws yog Paeoniflorin, Oxypaeoniflorin, Albiflorin, thiab Benzoylpaeoniflorin.

Dawb peony extract yog muab rho tawm los ntawm cov cag qhuav ntawm Paeonia lactiflora Pall., ib tsob nroj ntawm tsev neeg Ranunculaceae.Nws cov ntsiab lus tseem ceeb yog paeoniflorin, uas tuaj yeem siv dav tsis yog hauv kev kho mob nkaus xwb tab sis kuj tseem nyob hauv kev lag luam tshuaj pleev ib ce.Dawb peony extract yog qhov ua tau zoo PDE4 kev ua haujlwm inhibitor.Los ntawm inhibiting PDE4 kev ua haujlwm, nws tuaj yeem ua rau cAMP ntawm ntau yam kab mob thiab lub cev tiv thaiv kab mob (xws li neutrophils, macrophages, T lymphocytes thiab eosinophils, thiab lwm yam) ncav cuag qhov siab txaus los tiv thaiv kev ua kom cov hlwb ua kom mob thiab ua kom muaj kev tiv thaiv kab mob.Nws kuj muaj analgesic, antispasmodic, anti-ulcer, vasodilator, nce lub cev cov ntshav khiav, antibacterial, daim siab tiv thaiv, detoxifying, anti-mutagenic, thiab los tiv thaiv qog.

1,2,3,6-tetragalloyl qabzib, 1,2,3,4,6-pentagalloyl qabzib thiab cov kua nplaum hexagalloyl thiab heptagalloyl qabzib raug cais tawm ntawm tannin ntawm cov hauv paus dawb peony.Nws kuj muaj dextrorotatory catechin thiab volatile roj.Cov roj volatile mas muaj benzoic acid, peony phenol thiab lwm yam cawv thiab phenols.1. Paeoniflorin: molecular mis C23H28O11, molecular hnyav 480.45.Hygroscopic amorphous hmoov, [α]D16-12.8 ° (C = 4.6, methanol), tetraacetate yog xim tsis muaj koob muaju, mp.196 ℃.2. Paeonol: Synonyms yog paeonol, peony cawv, paeonal, thiab peonol.Cov mis mos molecular C9H10O3, molecular hnyav 166.7.Cov xim tsis muaj xim zoo li lub ntsej muag (ethanol), mp.50 ℃, me ntsis soluble hauv dej, tuaj yeem volatilize nrog dej vapor, soluble hauv ethanol, ether, acetone, chloroform, benzene thiab carbon disulfide.3. Lwm tus: Muaj ib qho me me ntawm oxypaeoniflorin, albiforin, benzoylpaeoniflorin, lactiflorin, monoterpene tshiab paeoniflorigenone nrog neuromuscular thaiv cov nas, 1,2,3,4,6-Pentagalloylglucose nrog cov tshuaj tua kab mob, gallicatenchinin, acid, ethyl gallate, tannin, β-sitosterol, qab zib, starch, mucus, thiab lwm yam.

Muaj nuj nqi:

1. Anti-inflammatory, antibacterial thiab antiviral teebmeem.Dawb peony extract muaj ib qho tseem ceeb inhibitory nyhuv ntawm qe dawb mob inflammatory edema nyob rau hauv nas thiab inhibits lub proliferation ntawm paj rwb pob granuloma.Tag nrho glycosides ntawm paeony muaj kev tiv thaiv kab mob thiab lub cev tiv thaiv kab mob rau cov nas uas muaj mob caj dab adjuvant.Dawb peony npaj muaj qee yam cuam tshuam rau Staphylococcus aureus, hemolytic Streptococcus, pneumococcus, Shigella dysenteriae, Typhoid bacillus, Vibrio cholerae, Escherichia coli thiab Pseudomonas aeruginosa.Tsis tas li ntawd, 1:40 peony decoction tuaj yeem tiv thaiv tus kab mob Jingke 68-1 thiab tus kab mob herpes.
2. Hepatoprotective nyhuv.Dawb peony extract muaj qhov cuam tshuam tseem ceeb rau lub siab puas tsuaj thiab SGPT nce los ntawm D-galactosamine.Nws tuaj yeem txo SGPT thiab rov ua rau daim siab mob hlwb thiab necrosis kom zoo.Cov ethanol extract ntawm dawb peony cag tuaj yeem txo qhov nce hauv tag nrho cov haujlwm ntawm lactate dehydrogenase thiab isoenzymes hauv cov nas uas mob siab rau mob los ntawm aflatoxin.Tag nrho glycosides ntawm paeony tuaj yeem cuam tshuam qhov nce hauv SGPT thiab lactate dehydrogenase hauv cov nas uas tshwm sim los ntawm carbon tetrachloride, thiab muaj kev cuam tshuam rau eosinophilic degeneration thiab necrosis ntawm daim siab nqaij.
3. Antioxidant nyhuv: Dawb peony cag extract TGP muaj antioxidant thiab cell membrane stabilizing teebmeem, thiab tej zaum yuav muaj ib tug scavenging nyhuv ntawm dawb radicals.
4. Cov kab mob plawv cov teebmeem Dawb peony extract tuaj yeem nthuav dav cov hlab ntsha ntawm lub plawv cais, tiv thaiv mob myocardial ischemia hauv nas los ntawm pituitaryin, thiab txo qis peripheral vascular tsis kam thiab nce ntshav txaus thaum txhaj rau hauv cov hlab ntsha.Paeoniflorin kuj tseem muaj cov nyhuv dilating ntawm cov hlab ntsha hauv cov hlab ntsha thiab cov hlab ntsha peripheral, thiab ua rau txo qis ntshav siab.Kev tshawb fawb tau pom tias paeoniflorin, ib qho extract ntawm dawb peony cag, muaj kev cuam tshuam rau ADP-induced platelet aggregation nyob rau hauv cov nas nyob rau hauv vitro.
5. Cov teebmeem ntawm plab hnyuv dawb peony extract muaj cov nyhuv inhibitory ntawm kev ua haujlwm ntawm txoj hnyuv hyperexcitability thiab contraction tshwm sim los ntawm barium chloride, tab sis tsis muaj kev cuam tshuam rau qhov contraction los ntawm acetylcholine.Cov dej sib xyaw ua ke ntawm licorice thiab dawb peony cag (0.21g) muaj qhov cuam tshuam tseem ceeb ntawm kev txav ntawm txoj hnyuv du hauv cov luav hauv vivo.Qhov sib xyaw ua ke ntawm ob yog qhov zoo dua li ntawm ib leeg, thiab cov nyhuv txo qis yog muaj zog dua li qhov amplitude-txo cov nyhuv.Qhov txo qis hauv plab hnyuv ntau zaus 20 mus rau 25 feeb tom qab kev tswj hwm yog 64.71% thiab 70.59% ntawm qhov ntawd hauv pawg tswj hwm ib txwm muaj, feem, thiab muaj zog dua li ntawm atropine (0.25 mg) hauv pawg tswj hwm zoo.Paeoniflorin muaj inhibitory cuam tshuam rau cov kab mob hauv cov hnyuv thiab hauv vivo gastric motility hauv guinea npua thiab nas, nrog rau cov nqaij nas uterine du, thiab tuaj yeem tiv thaiv kev sib kis los ntawm oxytocin.Nws muaj cov nyhuv synergistic nrog Chemicalbook cawv extract FM100 ntawm licorice.Paeoniflorin muaj qhov cuam tshuam loj heev rau cov kab mob hauv plab hnyuv hauv cov nas uas raug ntxias los ntawm kev ntxhov siab.
6. Sedative, analgesic, thiab anticonvulsant cuam tshuam.Dawb peony txhaj thiab paeoniflorin ob leeg muaj sedative thiab analgesic teebmeem.Kev txhaj tshuaj me me ntawm paeoniflorin rau hauv lub hlwb ventricles ntawm cov tsiaj tuaj yeem ua rau muaj kev pw tsaug zog zoo.Intraperitoneal txhaj ntawm 1g / kg ntawm paeoniflorin los ntawm dawb peony cag extract nyob rau hauv nas tuaj yeem txo cov tsiaj cov kev ua ub no, ua kom ntev lub sij hawm pw tsaug zog ntawm pentobarbital, inhibit qhov writhing cov tshuaj tiv thaiv ntawm nas los ntawm intraperitoneal txhaj ntawm acetic acid, thiab tiv thaiv pentylenetetrazole.Ua rau convulsions.Tag nrho glycosides ntawm paeony muaj cov teebmeem analgesic tseem ceeb thiab tuaj yeem txhim kho cov teebmeem analgesic ntawm morphine thiab clonidine.Naloxone tsis cuam tshuam rau cov nyhuv analgesic ntawm tag nrho glycosides ntawm paeony, qhia tias nws txoj cai analgesic tsis yog los txhawb opioid receptors.Peony extract tuaj yeem tiv thaiv kev ntxhov siab los ntawm strychnine.Paeoniflorin tsis muaj kev cuam tshuam rau cov leeg pob txha, yog li nws yog inferred tias nws cov nyhuv anticonvulsant yog lub hauv paus.
7. Cov txiaj ntsig ntawm cov ntshav: Paeony cawv extract tuaj yeem cuam tshuam cov platelet aggregation hauv cov luav vim yog ADP, collagen, thiab arachidonic acid hauv vitro.
8. Kev cuam tshuam rau lub cev tiv thaiv kab mob.Dawb peony cag tuaj yeem txhawb kev tsim cov kab mob spleen cell antibodies thiab tshwj xeeb txhim kho cov lus teb humoral ntawm nas rau yaj cov ntshav liab.Dawb peony decoction tuaj yeem tiv thaiv cov nyhuv inhibitory ntawm cyclophosphamide ntawm peripheral cov ntshav T lymphocytes hauv cov nas, rov qab mus rau qhov qub, thiab rov ua kom lub cev tsis muaj zog hauv lub cev.Tag nrho glycosides ntawm paeony tuaj yeem txhawb kev loj hlob ntawm splenic lymphocytes hauv cov nas uas raug ntxias los ntawm concanavalin, txhawb kev tsim cov α-interferon hauv tib neeg qaum ntshav leukocytes ntxias los ntawm Newcastle nqaij qaib plague tus kab mob, thiab muaj kev cuam tshuam bidirectional ntawm kev tsim cov interleukin-2 hauv nas. splenocytes induced los ntawm concanavalin.tswj cov nyhuv.
9. Ua kom muaj zog: Dawb peony cawv extract tuaj yeem ncua sijhawm ua luam dej ntawm nas thiab lub sijhawm muaj sia nyob hypoxic ntawm nas, thiab muaj qee yam ntxiv dag zog.
10. Anti-mutagenic thiab los tiv thaiv qog nqaij hlav Dawb peony extract tuaj yeem cuam tshuam nrog kev ua haujlwm enzyme ntawm S9 sib tov, thiab tuaj yeem ua rau cov metabolites ntawm benzopyrene thiab inhibit nws cov nyhuv mutagenic.

11. Lwm yam teebmeem (1) Antipyretic nyhuv: Paeoniflorin muaj cov nyhuv antipyretic rau cov nas uas ua npaws dag thiab tuaj yeem txo qis lub cev kub ntawm cov nas.(2) Nco-txhim kho cov nyhuv: Tag nrho glycosides ntawm paeony tuaj yeem txhim kho cov kev kawm tsis zoo thiab kev nco tau hauv cov nas uas tshwm sim los ntawm scopolamine.(3) Anti-hypoxic nyhuv: Tag nrho cov glycosides ntawm dawb paeony tuaj yeem ua kom ntev lub sij hawm ciaj sia ntawm cov nas nyob rau hauv ib txwm muaj siab thiab hypoxia, txo tag nrho cov pa oxygen noj ntawm cov nas, thiab txo qhov kev tuag ntawm cov nas vim yog poov tshuaj cyanide lom thiab hypoxia.