Aha: CDP-CHOLINE, CITICOLINE
Aha kemịkal: cytidine5'-diphosphatecholine
Ụdị ihe omimi: C14H26N4O11P2
CAS: 987-78-0
Einecs NO:213-580-7
Ụdị arọ: 488.33
Apearance: Gbanyụọ ntụ ntụ ọcha.
Ịdị ọcha: 98%
Aha kemịkal: cytidine5'-diphosphatecholine
Ụdị ihe omimi: C14H26N4O11P2
CAS: 987-78-0
Einecs NO:213-580-7
Ụdị arọ: 488.33
Apearance: Gbanyụọ ntụ ntụ ọcha.
Ịdị ọcha: 98%
Citicoline (INN), nke a makwaara dị ka cytidine diphosphate-choline (CDP-Choline) ma ọ bụ cytidine 5'-diphosphocholine bụ nootropic.Ọ bụ etiti na ọgbọ nke phosphatidylcholine sitere na choline.
Nnyocha na-egosi na ihe mgbakwunye CDP-choline na-abawanye njupụta dopamine receptor densities, ma na-atụ aro na CDP-choline supplementation na-enyere aka igbochi mmebi ncheta nke sitere na ọnọdụ gburugburu ebe obibi na-adịghị mma.Nnyocha mbụ achọpụtala na ihe mgbakwunye citicoline na-enyere aka melite nlebara anya na ike iche echiche ma nwee ike ịba uru na ọgwụgwọ nsogbu nlebara anya.
E gosikwara na Citicoline na-ebuli ACTH n'adabereghị na ọkwa CRH yana ịkwalite ntọhapụ nke hormones axis HPA ndị ọzọ dị ka LH, FSH, GH na TSH na nzaghachi na ihe ndị na-ewepụta hypothalamic.Mmetụta ndị a na ọkwa hormone HPA nwere ike ịba uru maka ụfọdụ ndị mmadụ mana ha nwere ike inwe mmetụta na-adịghị mma na ndị nwere ọnọdụ ahụike na-egosipụta ACTH ma ọ bụ cortisol hypersecretion gụnyere PCOS, ụdị ọrịa shuga II na nnukwu nsogbu ịda mbà n'obi.
Nnyocha na-egosi na ihe mgbakwunye CDP-choline na-abawanye njupụta dopamine receptor densities, ma na-atụ aro na CDP-choline supplementation na-enyere aka igbochi mmebi ncheta nke sitere na ọnọdụ gburugburu ebe obibi na-adịghị mma.Nnyocha mbụ achọpụtala na ihe mgbakwunye citicoline na-enyere aka melite nlebara anya na ike iche echiche ma nwee ike ịba uru na ọgwụgwọ nsogbu nlebara anya.
E gosikwara na Citicoline na-ebuli ACTH n'adabereghị na ọkwa CRH yana ịkwalite ntọhapụ nke hormones axis HPA ndị ọzọ dị ka LH, FSH, GH na TSH na nzaghachi na ihe ndị na-ewepụta hypothalamic.Mmetụta ndị a na ọkwa hormone HPA nwere ike ịba uru maka ụfọdụ ndị mmadụ mana ha nwere ike inwe mmetụta na-adịghị mma na ndị nwere ọnọdụ ahụike na-egosipụta ACTH ma ọ bụ cortisol hypersecretion gụnyere PCOS, ụdị ọrịa shuga II na nnukwu nsogbu ịda mbà n'obi.
Asambodo nyocha
| Ozi ngwaahịa | |
| Aha ngwaahịa: | Citicoline (CDP-Choline) |
| Nọmba CAS: | 987-78-0 |
| Usoro ihe omimi: | C14H26N4O11P2 |
| Ogbe Mba. | TRB-CDP-20190620 |
| Ụbọchị MFG: | Ọnwa Isii 20,2019 |
| Ihe | Nkọwapụta | Nsonaazụ ule |
| Ngwa ndị na-arụ ọrụ | ||
| Nnwale (%Na ebe akpọnwụwo) | 98.0% ~ 102.0% nke HPLC | 100.30% |
| Njikwa anụ ahụ | ||
| Ọdịdị | Ntụ ntụ kristal dị mma | Na-akwado |
| Agba | Ọcha ka Gbanyụọ Ọcha | Na-akwado |
| njirimara | NMR | Na-akwado |
| PH | 2.5-3.5 | 3.3 |
| Ọnwụ na ihicha | 1.0% kacha | 0.041% |
| Mmiri | 1.0% kacha | 0.052% |
| 5'-CMP | NMT1.0% | 0.10% |
| Njikwa kemịkalụ | ||
| Ọla dị arọ | NMT10PPM | Na-akwado |
| Arsenic (As2O3) | NMT1PPM | Na-akwado |
| Sulfate (SO4) | NMT 0.020% | Na-akwado |
| Ígwè (Fe) | NMT10PPM | Na-akwado |
| Chloride (Cl) | NMT 0.020% | Na-akwado |
| Ihe mgbaze | Nzute ọkọlọtọ EU/USP | Na-akwado |
| Njikwa microbiological | ||
| Ngụkọta ọnụ ọgụgụ efere | 10,00cfu/g Max | Na-akwado |
| Yist & ebu | 100cfu/g Max | Na-akwado |
| E.Coli | Na-adịghị mma/10g | Na-akwado |
| Salmonella sp. | Na-adịghị mma/25g | Na-akwado |
| Staph Aureus | Na-adịghị mma/10g | Na-akwado |
| Pseudomonas aeruginosa | Na-adịghị mma/25g | Na-akwado |
| Mbukota na Nchekwa | ||
| Nkwakọ ngwaahịa | Kwakọba n'ime akwụkwọ-drum.25Kg/Drum 1Kg kwa akpa rọba | |
| Nchekwa | Chekwaa n'ime akpa mechiri emechi nke ọma pụọ na mmiri na ìhè anyanwụ. | |
| Ndụ shelf | Afọ 2 ma ọ bụrụ na ejiri akara ma chekwaa ya nke ọma. | |
| Ozi ndị ọzọ nke TRB | ||
| Rasambodo egulation | ||
| Asambodo USFDA, CEP, KOSHER HALAL GMP ISO | ||
| Ogo a pụrụ ịdabere na ya | ||
| Ihe fọrọ nke nta ka ọ bụrụ afọ 20, mbupụ mba na mpaghara 40, ihe karịrị 2000 batches mepụtara TRB enweghị nsogbu ọ bụla, usoro ịdị ọcha pụrụ iche, adịghị ọcha na njikwa ịdị ọcha na-ezute USP, EP na CP | ||
| Sistemụ Ogo zuru oke | ||
|
| ▲ Sistemụ mmesi obi ike | √ |
| ▲ njikwa akwụkwọ | √ | |
| ▲ Sistemụ nkwado | √ | |
| v Sistemụ Ọzụzụ | √ | |
| v Protocol nyocha nke ime | √ | |
| ▲ Suppler Audit Sistemụ | √ | |
| ▲ Sistemụ akụrụngwa akụrụngwa | √ | |
| ▲ Sistemụ Njikwa Ihe | √ | |
| v Sistemụ njikwa mmepụta | √ | |
| ▲ Sistemụ akara ngosi nkwakọ ngwaahịa | √ | |
| v Sistemụ njikwa ụlọ nyocha | √ | |
| ▲ Sistemụ nkwado nkwenye | √ | |
| ▲ Sistemụ ihe gbasara iwu | √ | |
| Jikwaa isi mmalite na usoro niile | ||
| A na-achịkwa nke ọma ngwa ngwa niile, ngwa ngwa na ihe nkwakọ ngwaahịa. Ngwa akụrụngwa na ngwa ngwa na ihe nkwakọ ngwaahịa ndị na-ebubata ya na nọmba US DMF. Ọtụtụ ndị na-ebubata ihe dị ka nkwa ọkọnọ. | ||
| Ụlọ ọrụ nkwado siri ike iji kwado | ||
| Institute of botany/Institution of Microbiology/Academy of Science and Technology/University | ||
