Dzina lazogulitsa:Levery Leaf ConvertApigenin 98%
Dzina la Latin: Apium Ngalens L.
Cas No: 520-36-5
Chomera chomera chomwe chimagwiritsidwa ntchito: tsamba
Zosakaniza:Apigenin
Tankhana:Apigenin98.0% ndi HPLC
Mtundu: zofiirira mpaka ufa wachikasu wokhala ndi fungo ndi kukoma
Mkhalidwe wa GMO: GMO Free
Kulongedza: Mu 25kgs Drum
Kusungirako: Sungani chidebe chosavomerezeka, chowuma, kutalikirana ndi kuwala kwamphamvu
Moyo wa alumali: miyezi 24 kuyambira tsiku lopanga
Udzu winawake kutulutsa 98% Sepigenin: Kupanga kwachilengedwe kwachilengedwe kwa thanzi labwino
Kuzindikira Zowonjezera
Udzu winawake kutulutsa 98% SepigeninKodi zachilengedwe zoyera zimachokera ku mbewu zaApium Hopens, oyenera kuti apereke 98% Apigenin - Flavonoict Flavovooned yomwe idadziwika bwino chifukwa cha thanzi lake. Kutulutsa kumeneku kumapangidwa kudzera mu madzi apamwamba a ethanol ndi njira zapamwamba komanso njira zoyendetsedwa, ndikuwonetsetsa kuti ndi kukhazikika koyenera komanso chitetezo. Zoyenera chakudya cha mtedza wa mtedza, kugwiritsa ntchito zakudya zamankhwala, komanso kugwiritsa ntchito mankhwala azitsamba azitsamba ndi kutsimikizika kwamakono kwa sayansi.
Zabwino zaumoyo
- Thandizo la mtima
- Kuchepetsa kuthamanga kwa magazi & cholesterol: kumakhala ndi Phulhaldes (mwachitsanzo, 3-n-nglylllfal mitsempha yamagazi, TC, ntll-C), ndikusintha kufalikira, kuchirikiza kufalikira, kuchirikiza kufalikira, kuchirikiza kufalikira, kuchirikiza kufalikira, kuchirikiza kufalikira, kuchirikizira mizimu.
- Zotsatira za Anti-Hypertensingyfy: zimawonetsedwa m'mayesero azachipatala kuti zithandizirena ndi ma calcium / potaziyamu m'maselo amisala, imachepetsa chiopsezo cha matenda.
- Odana ndi zotupa & antioxidant katundu
- Ophatikizira matenda otupa olumikizidwa ndi matenda a nyamakazi, matenda a chiwindi, ndi matenda amtima kudzera pa flavonoids (apigenin, quercetin) ndi polysaccharides.
- Amalowerera ma radicals aulere ndi acids acid (caffec acid, acid acid), kuteteza ku zovuta za oxinatikiti ndi kuwonongeka kwa ma cell.
- Hepatoprrotective & diestive othandizira
- Amachepetsa kuchuluka kwa mafuta, kumathandizanso ntchito ezzyme, ndipo kumalimbikitsa kukhazikika powonjezera BILE.
- Amachita ngati diuretic, osinthika kutulutsa, ndikuthandizira thanzi la m'matumbo mwa kusanja kwa m'mimba ndikuchepetsa ulcer.
- Kuteteza khansa & chitetezo
- Apigenin amalepheretsa chotupa pothamangitsa mahomoni pantchito, kutsekereza kuchuluka kwa cell, ndikuteteza kukhulupirika kwa DNA.
- Polyacetylenes ndi mankhwala antimicrobial ma bactera amalimbana ndi matenda a mabakiteriya (mwachitsanzo, UTIS) ndikulimbitsa chitetezo chamthupi.
- Metabolic & Kupititsa patsogolo
- Kukweza mitochondrial ntchito, kasamalidwe kolemera kwambiri, ndikuwonjezera masewera olimbitsa thupi pakukonza kagayidwe ka mitud.
- Imathandizira kulimbitsa thupi komanso thanzi kudzera mu gawo la Apigenin mu neurogeneis ndikuchepetsa kupsinjika.
Mapulogalamu
- Nthambizi: zopangidwa mu makapisozi (500-1500 mg / tsiku) kuti mukhale ndi thanzi la mtima, anti-ukalamba, komanso kuthandizidwa ndi chitetezo.
- Zakudya zogwira ntchito: zowonjezeredwa m'mphepete mwa nyanja, mapuloteni, ndi zokhwasula za metabolic ndi antioxidant zopindulitsa.
- Mankhwala ogwiritsa ntchito mankhwala: ogwiritsidwa ntchito mu antihypertensive mafomu, mankhwalawa hepatoprotective, ndi anti-khansa molunjika.
- Zokongoletsa
- Kukomerera Mery: kumathandizira mapangidwe otchinga m'miyoyo, masuzi, ndi nyama ngati njira yachilengedwe yopangira zowonjezera.
Zolemba zaluso
- Yogwira pophika: Apigenin ≥98% (HPLC).
- Njira yodulira: ethanol-madzi osungunuka, sparay-youma ndi Maltodextrin.
- Maonekedwe: chabwino choyera mpaka ufa.
- Zivomeredzo: osakhala a gmo, olumala, alibe zowonjezera.
Chifukwa chiyani tisankhe?
- Kusinthana: kupezeka mu ufa wambiri, makapisozi, kapena amadzimadzi amadzimadzi a zilembo zapadera.
- Kutumiza mwachangu: Kutumizidwa kudzera pa DHL / FedEx (masiku 5-10) kapena masiku 15-45).
- Chitsimikizo Chachikulu: Gulu lachitatu lomwe limayesedwa loyera, potency, ndi zitsulo zolemera.
- Sammes aulere: 5-10 g zitsanzo zoperekedwa kutsimikizika kwa labu.
Chitetezo & kugwiritsa ntchito
- Mlingo: 500-1500 mg tsiku ndi tsiku, zosinthidwa kukhala mapangidwe ake.
- Mosamala: Mukhoza kulumikizana ndi mankhwala a Cyp3a4-metabolid (mwachitsanzo, matonthozi, anticoagulants). Funsani wopereka zaumoyo ngati ali ndi pakati kapena pa mankhwala
Anti-chotupa
Apigenin amatenga gawo lofunikira pakupewa khansa popewa apoptosis m'maselo osiyanasiyana.
Khansa ya Ovarian:
Kafukufuku wina adapezeka kuti Apigenin amatha kuletsa kukula, kuchulukana, ndikusamutsa Ca-Ov3 (selo ya khansa ya anthu); Imapangitsa apoptosis a Ca-Ov3 kudzera pa kusunga khansa maselo a stasis mu G2 / M gawo. Zotsatira zake zimagwirizana ndi nthawi ndi mlingo.
Khansa ya pancreatic:
Apigenin amatha kuletsa kuchuluka kwa ma cell a khansa ya kapamwamba. Apigenin ali ndi mawonekedwe a chotupa pochepetsa gwero la glucose, lomwe ndi chakudya chomwe ma cell akhwangwala amakhala. Kupatula apo, Apigenin amatha kusintha mphamvu ya mankhwala a chemotherapy- gemcitabine.
Chemo
Zinapezeka kuti Apigenin otsika anali ndi cytotoxic yotsika ndipo sakanakhoza kupangitsa kuti khungu likhale mneloid leukemia (HL-60) ku Apoptosis moyenera. Komabe, apigenin amatha kukulitsa zotsatira za Cisplatin (DDP) pa HL-60 Cell play pophatikiza ndi mitundu yosiyanasiyana ya DDP. Chifukwa chake Apigenin amatha kukhala ndi vuto la chemotherapy pa HL-60; Kukhazikika kochepa kwa apigenin kungachepetse kukana kwa HL-60 maselo a chemotherapy - omwe angakhale okhudzana ndi pansi-lamulo la NF-2. (Nf-KB ndi mtundu wa mapuloteni omwe amayendetsa DNA Kulemba kwa DNA, kupanga kwa cytokines ndi kupulumuka kwa cell;
Chitetezo cha chiwindi
Apigenin amatha kuchepetsa kuvulala kwa chiwindi omwe amayambitsidwa ndi ischemia-reforfoision kudzera pakuwongoletsa milid peroxidation ndi scavengeng free radicals.
Apigenin amatha kuchepetsa kuvulala kwa chiwindi chifukwa cha kupsinjika kwa oxida chifukwa cha antioxidant komanso anti-yotsutsa-kutupa.
Kuyesa kwa pharmacorlim komwe kwatsimikizira kuti Apigenin ali ndi vuto lodziteteza ku chiwindi / hepatocyte chotchinga chakumwa mowa, ndipo makina ake oyambira akugwirizana ndi zopinga za chiwindi / hepatocyte mu chiwindi / hepatocyte.
Letsa Osteoporosis
Apigenin amalepheretsa Osteoblastogeneis, osteoclastogenesis, komanso amalepheretsa kutaya mafupa.
Apigenin amateteza minofu yamafupa pochepetsa kutaya mafupa m'thupi.
Kafukufuku wina wokhudzana ndi Mc3t3-e1, isteoblast chingwe cha cell omwe amachokera ku matenda a calculus (mbewa) Calvalis (Mouse) Calvaria
Apigenin adaletsanso kusiyanitsa kwa 3t3-l1 adipose oyambitsa ma dipocytes mwamphamvu
Apigenin amalepheretsa kusiyanasiyana kwa osteoclasts kuchokera ku Raw264.7 ndipo kenako amalepheretsa ma osterooclasts oyipitsitsa. Ikhozanso kuchititsa OSTONALAST OPOPTOsis ndikuyika fupa.
Anti-yotupa ndi anti-oxidant ntchito
Apigenin amaletsa njira yotupa, imachulukitsa milingo ya il-10 ndikusintha magawo osinthanitsa okopa
Apigenin amalepheretsa cytokines yotupa ndipo imapangitsa kupanga ma cytokiine otupa.
Mabuku ena amati apigenin amayamwa matupi otupa ophatikizika ndi mavuto a oxida pa minofu yosinthira ma trans oxida, ma enzymes a enzyme, ndi ma enzyme ena angapo.
Kuwongolera kwa Endocrine
Apigenin amatha kuwongolera shuga, kuchitira chithokomiro ndikuwongolera lipid peroxidation.idinapezeka kuti apigenin amatha kukula kwa shuga ndi ntchito ya glucose-6.
Apigenin adasinthira zotsatira za kuchuluka kwa seramu cholesterol, chiwonjezeko chiwindi milid peroxidation (lpo) ndikuchepetsa zinthu za antioasease (amphaka) mu nyama za Alloxan.
Mu nyama zokhala ndi shuga wokhazikika, apigenin amathanso kuchepetsa seum cholesterol ndi chiwindi Lipid peroxid, ndikuwonjezera ntchito ya antioxidants m'maselo.
Pharcocological katundu wa apigenin
Apigenin adalimbikitsidwa kwambiri m'zaka zaposachedwa, monga momwe amathandizira pazachipatala chifukwa cha zovuta zake ndi zovuta zake pafupipafupi ndi zotsatira zake zotsutsana ndi ma cell a khansa pafupipafupi. Pali zochuluka za umboni wofufuzira yemwe wasonyeza Apigenin ali ndi njira zambiri zothandizira kuthana ndi matenda ambiri