Aha ngwaahịa:PRL-8-53
OAha ya: Methyl 3- (2- (benzylmethylamino) ethyl) benzoate hydrochloride
3- (2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride
3- (2- (Methyl (phenylmethyl) amino) ethyl) benzoic acid methyl ester hydrochloride.
Nọmba CAS:51352-87-5
Nyocha: 98%
Ọdịdị: White ntụ ntụ
Kedu ka PRL-8-53 si arụ ọrụ?
PRL-8-53 sitere na nchikota benzoic acid na phenylmethylamine.Usoro kemịkalụ nke a na-emepụta site na nchikota nke ogige abụọ a na-eme ka ngwakọta nke nwere ike imekọrịta ihe na ndị na-anabata cholinergic, nke na-etinye aka n'ịgbanwe ebe nchekwa na usoro mmụta n'ime ụbụrụ.PRL-8-53 makwaara na ọ nwere ike (na-abawanye mmetụta nke) dopamine na akụkụ ụfọdụ na-egbochi ndị na-anabata serotonin.Dr. Nikolaus Hansl kwenyere na profaịlụ mmetụta a nwere ike iduga ngbanwe nke nguzozi na sistemụ neurotransmitter CNS ma mee ka ọrụ ọgụgụ isi dịkwuo mma.
Enwere naanị otu ọmụmụ ụlọ ọgwụ nke mmadụ na-ebute ụzọ iji nyochaa mmetụta nke ọgwụ ahụ ma gosipụta ọganihu na ebe nchekwa okwu, oge mmeghachi omume na-ahụ anya na njikwa moto, karịsịa na ndị nọ n'afọ 30. Ndị agadi na-emekarị ka ha bụrụ ndị ọzọ n'okpuru ebe nchekwa. na mbelata nke ọgụgụ isi, ya mere, ebe nchekwa na ihe mgbakwunye na-eme ka ọgụgụ isi na-arụ ọrụ nke ọma na ha.
Ọrụ RPL-8-53:
Kwalite ọgụgụ isi
kwalite ebe nchekwa na ike ịdabere
Melite ike ụbụrụ iji dozie nsogbu ma chebe ya pụọ na mmerụ ahụ kemịkal ma ọ bụ anụ ahụ ọ bụla
Kwalite ọkwa mkpali
Kwalite njikwa nke usoro ụbụrụ cortical/subcortical
Melite nghọta mmetụta
Usoro onunu ogwu na mmetụta
Ozi patent dị maka PRL 8-53 na-atụ aro oke nke 0.01-4mg/kg nke arọ ahụ.Otú ọ dị, dị ka nke ahụ bụ nnukwu oke, oke dị mma bụ 0.05-1.2 mg / kg.Nke a na-atụgharị na 3.4mg-81.6mg maka onye 150 pound na 4.55mg-109mg maka onye 200 pound.N'ime ule mmadụ, ọ nweghị mmetụta ọ bụla e dekọrọ;Otú ọ dị, a chọpụtara obere ọrụ moto na ụmụ oke na oke mgbe enyere ya nnukwu doses nke PRL 8-53.
