Osthole 98%

Fructus cnidii (Common Cnidium) ndi zitsamba zapachaka, kutalika kwa 30-80cm.Tsamba la Fructus cnidii ndi losinthika, inflorescence yacompundumbel.Cremocarp, ellipsoidal, 2-4 mm kutalika, pafupifupi 2 mm m'mimba mwake.Kunja imvi-chikasu kapena imvi-bulauni;okhala ndi ma stylopods 2 opindika pamwamba, ndipo nthawi zina amakhala ndi phesi la zipatso zabwino m'munsi.Pamwamba pa ma mericarps okhala ndi zitunda zisanu zoonda komanso zazitali, zopindika pamwamba, zokhala ndi nthiti ziwiri zofiirira komanso zokwezeka pang'ono.Fructus cnidii's pericarp lax ndi wosalimba, wosasunthika mosavuta, njere yaying'ono, yotuwa komanso yamafuta.Kununkhira, kununkhira;kukoma, kupsa mtima, kozizira komanso dzanzi.

Osthol, yomwe imadziwikanso kuti methoxyparsley, parsley methyl ether, ndi mankhwala a coumarin, mu maambulera chomera osthol osthol amakhala okwera, otchedwa osthol.Mu 1909, Herzog ndi Krohn anapeza koyamba osthol kuchokera ku mizu ya ambulera ya europhus.Pakalipano, amapezeka kwambiri muzomera, makamaka mu umbelliferae ndi rutaceae, komanso mumagulu ochepa a compositae ndi nyemba.
Cnidium cnidium yamalonda imachokera ku zipatso zouma komanso zakupsa za cnidium cnidium.Cnidium imafalitsidwa makamaka ku guangxi, jiangsu, anhui, shandong, hebei, ndi zina zotero. Chifukwa cha ntchito zake zosiyanasiyana zamoyo, cnidium imagwiritsidwa ntchito kwambiri muzodzoladzola, mankhwala ndi ulimi.

Dzina la malonda: Osthole 98%

Kufotokozera:98% ndi HPLC

Dzina Lachilatini:C.monnieri (L.) Cusson

Gwero la Botanic: Common Cnidium Fruit Extract

Nambala ya CAS: 484-12-8

Chigawo Chomera Chogwiritsidwa Ntchito: Mbewu

Utoto: Ufa wofiirira mpaka woyera wokhala ndi fungo labwino komanso kukoma kwake

Mkhalidwe wa GMO: GMO Yaulere

Kulongedza: mu 25kgs fiber ng'oma

Kusungirako: Sungani chidebe chosatsegulidwa pamalo ozizira, owuma, Khalani kutali ndi kuwala kwamphamvu

Shelf Life: Miyezi 24 kuyambira tsiku lopangidwa

Ntchito:

-Osthole amatha kuchulukitsa kutulutsa kwa umuna, kudzutsa chilakolako chogonana komanso kukhala ndi mphamvu yopatsa mphamvu

-Osthole amatha kuyanika chinyontho komanso kupha mphutsi, kutulutsa kuzizira komanso kutulutsa mphepo, kutenthetsa impso.

limbitsa yin.

-Osthole ali ndi ntchito yochotsa mphumu ndi antifungus, antivayirasi.

Antiarrhythmic zotsatira

Madzi ochotsera madzi ndi coumadin okwana kuchokera ku fructus cnidium ali ndi zotsatira zodziwikiratu pa chloroform induced ventricular fibrillation mu mbewa ndi calcium chloride induced ventricular fibrillation mu makoswe.Fructus cnidium ndi zanthoxylum acetaminophen alinso ndi zotsatira za pharmacological ndipo amatha kusintha ventricular electrofibrillation threshold mu akalulu.Kutulutsa kwamadzi, coumarin, cnidium, ndi phenols za zanthoxylum zinali ndi zotsatira zolepheretsa kuyenda kwa ayoni a sodium mu nembanemba ya myocardial cell.

Antihypertensive, kuletsa kufalikira kwa mitsempha

Osthol anali ndi zotsatira zoyipa za inotropic kumanzere kwa atrium ya nkhumba zapayokha komanso zotsatira zoyipa pafupipafupi kumanzere kwa atrium ya nkhumba zapayokha.Kuwonjezera pa polarization yomwe inayambitsidwa ndi norepinephrine, CaCl2 ndi high K +, aorta contraction dose-response curve ya akalulu inasunthidwa kumanja ndipo kuyankha kwakukulu kunachepetsedwa, kusonyeza ntchito ya biosynthetic pawiri mu kupumula minofu yosalala ya mitsempha.Fructus cnidium imakhala ndi antihypertensive kwenikweni.

Zotsatira pa kupuma dongosolo

Cnidium monnieri okwana coumarin ndi kumasuka ndi mankhwala (histamine ndi acetylcholine) chifukwa cha spasms bronchial ndi diastole bronchus udindo mwachindunji, ntchito imeneyi akhoza kukhala B - adrenaline cholandilira blockers chipika ndi propranolol, mbewa pambuyo okwana coumarin cnidium monnieri, mwachionekere kuwonjezera kuchuluka kwa phenol wofiira. kukhetsa mu thupi, limasonyeza amphamvu expectoranting kanthu.

Zotsutsana ndi kutupa

Cnidium cnidium ndi phenolic zanthoxylum amatha kuletsa kutupa kwa khutu kwa mbewa chifukwa cha xylene komanso kuwonjezeka kwa capillary permeability m'mimba chifukwa cha asidi acetic.Osthol ndi acetonol zinali ndi zotsatira zolepheretsa phazi kutupa mu makoswe ndi makoswe okhala ndi adrenal resection.Osthol ikhoza kuchepetsanso PGE zomwe zili m'matenda otupa a phazi lotupa mu makoswe, koma osthol sanakhudze zomwe zili mu PGE m'matenda otupa a phazi lotupa mu makoswe.

Zotsatira za dongosolo lamanjenje

Coumarin yonse ya cnidium cnidium imalepheretsa dongosolo lapakati la mitsempha.Osthol imatha kupititsa patsogolo hypnotic zotsatira za pentobarbital sodium pa subthreshold hypnotic mlingo mu mbewa, ndipo hypnotic zotsatira zake zimagwirizana ndi mlingo.Cnidium cnidium imatha kulimbikitsa kuphunzira ndi kukumbukira mbewa, ndikuwongolera kwambiri kukumbukira kukumbukira, kuphatikiza ndi DirectAntiarrhythmic effect.

Madzi ochotsera madzi ndi coumadin okwana kuchokera ku fructus cnidium ali ndi zotsatira zodziwikiratu pa chloroform induced ventricular fibrillation mu mbewa ndi calcium chloride induced ventricular fibrillation mu makoswe.Fructus cnidium ndi zanthoxylum acetaminophen alinso ndi zotsatira za pharmacological ndipo amatha kusintha ventricular electrofibrillation threshold mu akalulu.Kutulutsa kwamadzi, coumarin, cnidium, ndi phenols za zanthoxylum zinali ndi zotsatira zolepheretsa kuyenda kwa ayoni a sodium mu nembanemba ya myocardial cell.

Antihypertensive, kuletsa kufalikira kwa mitsempha

Osthol anali ndi zotsatira zoyipa za inotropic kumanzere kwa atrium ya nkhumba zapayokha komanso zotsatira zoyipa pafupipafupi kumanzere kwa atrium ya nkhumba zapayokha.Kuwonjezera pa polarization yomwe inayambitsidwa ndi norepinephrine, CaCl2 ndi high K +, aorta contraction dose-response curve ya akalulu inasunthidwa kumanja ndipo kuyankha kwakukulu kunachepetsedwa, kusonyeza ntchito ya biosynthetic pawiri mu kupumula minofu yosalala ya mitsempha.Fructus cnidium imakhala ndi antihypertensive kwenikweni.

Zotsatira pa kupuma dongosolo

Cnidium monnieri okwana coumarin ndi kumasuka ndi mankhwala (histamine ndi acetylcholine) chifukwa cha spasms bronchial ndi diastole bronchus udindo mwachindunji, ntchito imeneyi akhoza kukhala B - adrenaline cholandilira blockers chipika ndi propranolol, mbewa pambuyo okwana coumarin cnidium monnieri, mwachionekere kuwonjezera kuchuluka kwa phenol wofiira. kukhetsa mu thupi, limasonyeza amphamvu expectoranting kanthu.

Zotsutsana ndi kutupa

Cnidium cnidium ndi phenolic zanthoxylum amatha kuletsa kutupa kwa khutu kwa mbewa chifukwa cha xylene komanso kuwonjezeka kwa capillary permeability m'mimba chifukwa cha asidi acetic.Osthol ndi acetonol zinali ndi zotsatira zolepheretsa phazi kutupa mu makoswe ndi makoswe okhala ndi adrenal resection.Osthol ikhoza kuchepetsanso PGE zomwe zili m'matenda otupa a phazi lotupa mu makoswe, koma osthol sanakhudze zomwe zili mu PGE m'matenda otupa a phazi lotupa mu makoswe.

Zotsatira za dongosolo lamanjenje

Coumarin yonse ya cnidium cnidium imalepheretsa dongosolo lapakati lamanjenje.Osthol imatha kupititsa patsogolo hypnotic zotsatira za pentobarbital sodium pa subthreshold hypnotic mlingo mu mbewa, ndipo hypnotic zotsatira zake zimagwirizana ndi mlingo.Cnidium cnidium imatha kulimbikitsa kuphunzira ndi kukumbukira mbewa, ndikuwongolera kwambiri kukumbukira, kuphatikiza komanso tsankho la mbewa.

Anti-mutagenesis, anti-cancer effect

Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen ndi toxin ya zanthoxylum ali ndi ntchito yayikulu yolepheretsa mutagenesis wa aflatoxin B1.Madzi a cnidium amatha kuletsa S130 sarcoma, kutalikitsa masiku opulumuka ndikuletsa kukula kwa chotupa.

Anti-mutagenesis, anti-cancer effect

Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen ndi toxin ya zanthoxylum ali ndi ntchito yayikulu yolepheretsa mutagenesis wa aflatoxin B1.Madzi a cnidium amatha kuletsa S130 sarcoma, kutalikitsa masiku opulumuka ndikuletsa kukula kwa chotupa.

Mapulogalamu:

Osthole amagwiritsidwa ntchito kwambiri m'minda ya mankhwala a heath.Osthole angagwiritsidwe ntchito ngati mankhwala a tonic pa kusowa mphamvu kwa amuna, zosakaniza zogwira ntchito za mankhwala a matenda a gynecological.

Osthole amagwiritsidwa ntchito kwambiri m'minda yamankhwala.Osthole amagwiritsidwanso ntchito ngati mankhwala a tonic pa pachimake exudative khungu matenda.

Othandizira angapo azinthu zopangira ngati chitsimikizo chopereka.Mabungwe Ogwirizana Amphamvu kuti athandizireInstitute of botany/Institution of Microbiology/Academy of Science and Technology/University