Igama Lomkhiqizo:I-Uncaria Rhynchophylla Extract

Elinye Igama:I-Gou Teng Extract, I-Gambir Plant Extract

Umthombo we-Botanic:I-Uncaria rhynchophylla(Miq.）Miq.ex Havil.

Izithako ezisebenzayo:I-Rhynchophylline, i-Isorhynchophylline

Umbala:Brownimpushana enephunga sici nokunambitha

Ukucaciswa:1%-10%I-alkaloid ephelele ye-Uncaria

Isilinganiso Sokukhipha:50-100:1

Ukunyibilika:Incibilika ku-chloroform, i-acetone, i-ethanol, i-benzene, inyibilika kancane ku-ether ne-ethyl acetate.

I-GMOIsimo:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

I-Uncaria rhynchophylla (Miq.) Jacks isitshalo sohlobo lwe-Uncaria emndenini i-Rubiaceae.Isatshalaliswa kakhulu eJiangxi, Guangdong, Guangxi, Hunan, Yunnan nakwezinye izifunda.Njengomuthi wendabuko waseShayina ezweni lami, iziqu zawo eziboshwe kanye namagatsha anomlando omude wokusetshenziswa.I-Uncaria rhynchophylla ibanda kancane ngokwemvelo futhi inokunambitheka okumnandi.Ingena esibindini kanye ne-pericardium meridians.Inemiphumela yokususa ukushisa nokuthulisa isibindi, umoya ocishayo kanye nokudlikizeka okwehlisa umoya.Isetshenziselwa ubuhlungu bekhanda nesiyezi, imikhuhlane kanye nokudlikiza, isithuthwane nokudlikiza, i-eclampsia ngesikhathi sokukhulelwa, kanye nomfutho wegazi ophakeme.Kulolu cwaningo, izingxenye zamakhemikhali ze-Uncaria rhynchophylla (Miq.) Jacks zahlukaniswa ngokuhlelekile.Izinhlanganisela eziyishumi zahlukaniswa ku-Uncaria rhynchophylla.Ezinhlanu zazo zihlonzwe ngokuhlaziya izakhiwo zamakhemikhali nokuhlanganisa i-UV, i-IR, i-1HNMR, i-13CNMR nenye idatha ye-spectral, okuyi-β-sitosterol Ⅰ, i-ursolic acid Ⅱ, isorhynchophylline Ⅲ, i-rhynchophylline Ⅳ, ne-daucosterol.I-Rhynchophylline ne-isorhynchophylline yizingxenye ezisebenzayo ze-Uncaria rhynchophylla zokwehlisa umfutho wegazi.Ngaphezu kwalokho, ukuhlolwa kwe-orthogonal ye-L9 (34) kwasetshenziswa ukuze kuthuthukiswe inqubo yokukhipha i-Uncaria rhynchophylla.Ekugcineni, inqubo efanelekile yanqunywa ukuthi isebenzisa i-ethanol engu-70%, ilawula izinga lokushisa lokugeza amanzi ku-80 ℃, ikhiphe kabili, ingeze izikhathi eziyi-10 nezikhathi zotshwala eziyi-8 ngokulandelana, futhi isikhathi sokuyikhipha sasingamahora ama-2 namahora ayi-1.5 ngokulandelana.Lolu cwaningo lusebenzise amagundane e-hypertensive (SHR) njengento yocwaningo futhi lwasebenzisa i-Uncaria rhynchophylla extract (ingqikithi ye-Uncaria rhynchophylla alkaloids, i-rhynchophylline nama-isomers we-rhynchophylla alkaloids) njengendlela yokungenelela ukuze kuhlolwe imiphumela yokuhlola ye-Uncaria rhynchophylla extract in spontaneously i-anti-hypertension kanye ne-anti-vascular remodeling.Imiphumela yabonisa ukuthi i-Uncaria rhynchophylla extract inomphumela wokwehlisa umfutho wegazi ku-SHR futhi ingathuthukisa ukulungiswa kwemithambo yemithambo kuwo wonke amazinga ku-SHR ngezinga elithile.