Dzina: CDP-CHOLINE, CITICOLINE
Dzina la mankhwala: cytidine5'-diphosphatecholine
Molecular formula: C14H26N4O11P2
CAS: 987-78-0
Einecs NO: 213-580-7
Kulemera Kwambiri: 488.33
Maonekedwe: Pa ufa woyera.
Chiyero: 98%
Dzina la mankhwala: cytidine5'-diphosphatecholine
Molecular formula: C14H26N4O11P2
CAS: 987-78-0
Einecs NO: 213-580-7
Kulemera Kwambiri: 488.33
Maonekedwe: Pa ufa woyera.
Chiyero: 98%
Citicoline (INN), yomwe imadziwikanso kuti cytidine diphosphate-choline (CDP-Choline) kapena cytidine 5'-diphosphocholine ndi nootropic.Ndi wapakatikati mu m'badwo wa phosphatidylcholine kuchokera ku choline.
Kafukufuku akuwonetsa kuti ma CDP-choline supplements amawonjezera kuchuluka kwa dopamine receptor, ndipo akuwonetsa kuti CDP-choline supplementation imathandizira kuletsa kuwonongeka kwa kukumbukira komwe kumachitika chifukwa chakusauka kwa chilengedwe.Kafukufuku woyambirira wapeza kuti mankhwala owonjezera a citicoline amathandizira kuwongolera malingaliro ndi mphamvu zamaganizidwe ndipo mwina atha kukhala othandiza pochiza vuto la kuchepa kwa chidwi.
Citicoline yasonyezedwanso kuti imakweza ACTH mopanda malire a CRH komanso kukulitsa kutulutsidwa kwa mahomoni ena a axis a HPA monga LH, FSH, GH ndi TSH poyankha zinthu zotulutsa hypothalamic.Zotsatirazi pamagulu a mahomoni a HPA zingakhale zopindulitsa kwa anthu ena koma zingakhale ndi zotsatira zosafunikira kwa iwo omwe ali ndi matenda omwe ali ndi ACTH kapena cortisol hypersecretion kuphatikizapo PCOS, matenda a shuga a mtundu wa II ndi matenda aakulu ovutika maganizo.
Kafukufuku akuwonetsa kuti ma CDP-choline supplements amawonjezera kuchuluka kwa dopamine receptor, ndipo akuwonetsa kuti CDP-choline supplementation imathandizira kuletsa kuwonongeka kwa kukumbukira komwe kumachitika chifukwa chakusauka kwa chilengedwe.Kafukufuku woyambirira wapeza kuti mankhwala owonjezera a citicoline amathandizira kuwongolera malingaliro ndi mphamvu zamaganizidwe ndipo mwina atha kukhala othandiza pochiza vuto la kuchepa kwa chidwi.
Citicoline yasonyezedwanso kuti imakweza ACTH mopanda malire a CRH komanso kukulitsa kutulutsidwa kwa mahomoni ena a axis a HPA monga LH, FSH, GH ndi TSH poyankha zinthu zotulutsa hypothalamic.Zotsatirazi pamagulu a mahomoni a HPA zingakhale zopindulitsa kwa anthu ena koma zingakhale ndi zotsatira zosafunikira kwa iwo omwe ali ndi matenda omwe ali ndi ACTH kapena cortisol hypersecretion kuphatikizapo PCOS, matenda a shuga a mtundu wa II ndi matenda aakulu ovutika maganizo.
Satifiketi Yowunikira
| Zambiri Zamalonda | |
| Dzina lazogulitsa: | Citicoline (CDP-Choline) |
| Nambala ya CAS: | 987-78-0 |
| Mapangidwe a maselo: | Chithunzi cha C14H26N4O11P2 |
| Gulu No. | TRB-CDP-20190620 |
| Mtengo wapatali wa magawo MFG: | Juni 20, 2019 |
| Kanthu | Kufotokozera | Zotsatira za mayeso |
| Yogwira Zosakaniza | ||
| Kuyesa(%.Pa Dried Base) | 98.0% ~ 102.0% ndi HPLC | 100.30% |
| Kulamulira mwakuthupi | ||
| Maonekedwe | Fine crystalline Powder | Zimagwirizana |
| Mtundu | Choyera mpaka Choyera | Zimagwirizana |
| Chizindikiritso | NMR | Zimagwirizana |
| PH | 2.5-3.5 | 3.3 |
| Kutaya pa Kuyanika | 1.0% Max | 0.041% |
| Madzi | 1.0% Max | 0.052% |
| 5'-CMP | NMT1.0% | 0.10% |
| Chemical Control | ||
| Zitsulo zolemera | Chithunzi cha NMT10PPM | Zimagwirizana |
| Arsenic (As2O3) | Chithunzi cha NMT1PPM | Zimagwirizana |
| Sulfate (SO4) | NMT 0.020% | Zimagwirizana |
| Chitsulo (Fe) | Chithunzi cha NMT10PPM | Zimagwirizana |
| Chloride (Cl) | NMT 0.020% | Zimagwirizana |
| Zotsalira za Solvent | Kukumana ndi EU/USP Standard | Zimagwirizana |
| Kuwongolera kwa Microbiological | ||
| Total Plate Count | 10,00cfu/g Max | Zimagwirizana |
| Yisiti & Mold | 100cfu/g Max | Zimagwirizana |
| E.Coli | Zoyipa / 10g | Zimagwirizana |
| Salmonella sp. | Zoyipa / 25g | Zimagwirizana |
| Staph Aureus | Zoyipa / 10g | Zimagwirizana |
| Pseudomonas aeruginosa | Zoyipa / 25g | Zimagwirizana |
| Kulongedza ndi Kusunga | ||
| Kulongedza | Ikani mu mapepala-ng'oma.25Kg / Drum 1Kg pa thumba la pulasitiki | |
| Kusungirako | Sungani mu chidebe chotsekedwa bwino kutali ndi chinyezi komanso kuwala kwa dzuwa. | |
| Shelf Life | Zaka 2 ngati atasindikizidwa ndikusungidwa bwino. | |
| Zambiri za TRB | ||
| Rcertification ya egulation | ||
| USFDA, CEP, KOSHER HALAL GMP ISO Zikalata | ||
| Ubwino Wodalirika | ||
| Pafupifupi zaka 20, kutumiza maiko 40 ndi zigawo, magulu oposa 2000 opangidwa ndi TRB alibe vuto lililonse, njira yapadera yoyeretsera, kuyeretsa ndi kuyeretsa kumakumana ndi USP, EP ndi CP | ||
| Comprehensive Quality System | ||
|
| ▲Njira Yotsimikizira Ubwino | √ |
| ▲ Kuwongolera zolemba | √ | |
| ▲ Njira Yotsimikizira | √ | |
| ▲ Njira Yophunzitsira | √ | |
| ▲ Protocol ya Internal Audit | √ | |
| ▲ Suppler Audit System | √ | |
| ▲ Makina Othandizira Zida | √ | |
| ▲ Dongosolo Loyang'anira Zinthu | √ | |
| ▲ Dongosolo Loyang'anira Zopanga | √ | |
| ▲ Packaging Labeling System | √ | |
| ▲ Laboratory Control System | √ | |
| ▲ Njira Yotsimikizira | √ | |
| ▲ Regulatory Affairs System | √ | |
| Sinthani Magwero Onse ndi Njira | ||
| Kuwongolera mosamalitsa zonse zopangira, zowonjezera ndi zoyikamo. Zokonda zopangira ndi zowonjezera ndi katundu wonyamula katundu ndi US DMF number.Several raw suppliers as supply assurance. | ||
| Mabungwe Ogwirizana Amphamvu kuti athandizire | ||
| Institute of botany/Institution of Microbiology/Academy of Science and Technology/University | ||
